Zobrazeno 1 - 10 of 27 pro vyhledávání: '"D. C. B Mills"'
1
Identification of a receptor for ADP on blood platelets by photoaffinity labelling
Autor: G Cristalli, D C B Mills
Publikováno v: Biochemical Journal. 291:875-881
The synthesis of a new analogue of ADP, 2-(p-azidophenyl)-ethythioadenosine 5′-diphosphate (AzPET-ADP), is described. This compound contains a photolabile phenylazide group attached to the ADP molecule by a thioether link at the purine 2 position.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7686e9c2d0657bbff5b31dcb2d9adc3
https://doi.org/10.1042/bj2910875
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3
Mapping of the P2U purinergic receptor gene to human chromosome 11q 13.5-14.1
Autor: D. C. B. Mills, Arbansjit K. Sandhu, Raghbir S. Athwal, Satya P. Kunapuli, Venkat R. Dasari
Publikováno v: Somatic cell and molecular genetics. 22(1)
We mapped a human P2U purinergic receptor gene to chromosome 11q13.5–14.1. Oligonucleotide primers complementary to a part of the human P2U purinergic receptor cDNA were used to amplify a region from genomic DNAs from a panel of mouse/human somatic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f131dccc2fcd26b4bff31795b5a561
https://pubmed.ncbi.nlm.nih.gov/8643996
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4
Chemical Agents That Inhibit Platelet Aggregation
Autor: D. C. B. Mills, J. B. Smith
Publikováno v: Biochemical Pharmacology of Blood and Bloodforming Organs ISBN: 9783642758676
The primary importance of platelets in the hemostatic process and their acknowledged involvement in thrombosis have led to an extensive investigation into the mechanisms of platelet adhesion and aggregation. Early studies of the factors which influen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec70c7d08336cf6e0398d599973bb72e
https://doi.org/10.1007/978-3-642-75865-2_10
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5
The Platelet Defect Associated with Albinism
Autor: R. M. Hardisty, Kanchana Ketsa-ard, D. C. B. Mills
Publikováno v: British Journal of Haematology. 23:679-692
Summary. Investigations on the blood of two albino women with a haemostatic defect have revealed a specific abnormality of their platelets. This consists of an inability of the platelets to store adenine nucleotides in a metabolically inert form, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117d896d8ce8180ee7b2169adfd95de3
https://doi.org/10.1111/j.1365-2141.1972.tb03483.x
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6
Membrane Active Drugs and the Aggregation of Human Blood Platelets
Autor: G. C. K. Roberts, D. C. B. Mills
Publikováno v: Nature. 213:35-38
The aggregation of human blood platelets is stimulated by ADP and other materials, and is known to take place in two stages. Studies with chlorpromazine, imipramine and related compounds indicate that they affect the second stage
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d8ed5d802a750758a39b7a56edffa9c
https://doi.org/10.1038/213035a0
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7
THE EFFECTS OF VARIOUS CHLORINE DERIVATIVES OF THYRONINE ON SERUM CHOLESTEROL CONCENTRATION AND MYOCARDIAL STIMULATION IN RATS AND HUMANS
Autor: D. M. Ireland, M. F. Oliver, W. F. J. Cuthbertson, G. S. Boyd, P. V. Elcoate, D. C. B. Mills
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 21:1579-1591
Chlorinated and iodinated thyronine derivatives were studied for their effects on serum and liver cholesterol and on hypertrophy of the cardiac ventricle, in the rat. Compounds characterized by higher ratios of cholesterol to cardiac effects were fou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d932e9bc04dd4158dee8a67d533d05
https://doi.org/10.1210/jcem-21-12-1579
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8
The influence on platelet aggregation of drugs that affect the accumulation of adenosine 3′:5′-cyclic monophosphate in platelets
Autor: J. B. Smith, D. C. B. Mills
Publikováno v: Biochemical Journal. 121:185-196
1. The involvement of intracellular 3′:5′-cyclic AMP in the inhibition of platelet aggregation by prostaglandin E1, isoprenaline and adenosine has been examined by a radiochemical technique. Platelet-rich plasma was incubated with radioactive ade
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54da902a3535ed1f711b23fec2ba360
https://doi.org/10.1042/bj1210185
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9
EFFECT OF DIET, OF 3:5-DIIODO-D-THYRONINE AND OF 3:5-DIIODO-4(4′-HYDROXY PHENOXY) PHENYL ACETIC ACID ON THE FORMATION AND REGRESSION OF ATHEROSCLEROTIC LESIONS IN THE RAT
Autor: D. C. B. Mills, W. F. J. Cuthbertson, D. M. Ireland, P. V. Elcoate, Patricia Shearley
Publikováno v: Journal of Endocrinology. 21:69-82
SUMMARY 1. Atherosclerotic lesions can be made to develop or regress in the albino rat by treatments that, respectively, elevate or depress the serum cholesterol concentration. 2. After young rats had been given a new diet for 45–72 days, the degre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::699c0aa0546483b810c41571d739b326
https://doi.org/10.1677/joe.0.0210069
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10
EFFECT OF COMPOUNDS RELATED TO THYROXINE ON SERUM AND LIVER CHOLESTEROL AND ON ATHEROSCLEROSIS AND HEART WEIGHTS IN RATS AND MICE
Autor: D. M. Ireland, P. V. Elcoate, D. C. B. Mills, Patricia Shearley, W. F. J. Cuthbertson
Publikováno v: Journal of Endocrinology. 21:45-68
SUMMARY 1. Methods are described for comparing the activity of compounds related to thyroxine in controlling the increases in cholesterol concentration in the serum and in the liver, and the increased sudanophilia in the cardiovascular system, after
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f285e1dd4cfb878b5949ed475c2f49
https://doi.org/10.1677/joe.0.0210045
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