Zobrazeno 1 - 10
of 298
pro vyhledávání: '"D. Buschmann"'
Autor:
Mohamad-Gabriel Alameh, Ashkan Tavakoli Naeini, Garima Dwivedi, Frederic Lesage, Michael D. Buschmann, Marc Lavertu
Publikováno v:
Polymers, Vol 16, Iss 17, p 2547 (2024)
Chitosan shows effective nucleic acid delivery. To understand the influence of chitosan’s molecular weight, dose, payload, and hyaluronic acid coating on in vivo toxicity, immune stimulation, biodistribution and efficacy, precisely characterized ch
Externí odkaz:
https://doaj.org/article/7d01ecce463a4a4da75e0547a3416a3b
Autor:
Manuel J. Carrasco, Suman Alishetty, Mohamad-Gabriel Alameh, Hooda Said, Lacey Wright, Mikell Paige, Ousamah Soliman, Drew Weissman, Thomas E. Cleveland, Alexander Grishaev, Michael D. Buschmann
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Carrasco et al. report a method that can predict the lipid nanoparticles (LNP) pKa from the structure of the ionizable lipid. They investigate the delivery efficiency for intramuscular and intravascular administration and propose design principles to
Externí odkaz:
https://doaj.org/article/bbdbf3686db74c9385304e3b47673ec7
Autor:
R. H. Schmitt, R. Kiesel, D. Buschmann, S. Cramer, C. Enslin, M. Fischer, T. Gries, Ch. Hopmann, L. Huebser, T. Janke, M. Kemmerling, K. Müller, L. Pelzer, M. Perau, M. Pourbafrani, V. Samsonov, P. Schlegel, M. Schopen, G. Schuh, T. Schulze, W. M. P. van der Aalst
Publikováno v:
Internet of Production ISBN: 9783030980627
In short-term production management of the Internet of Production (IoP) the vision of a Production Control Center is pursued, in which interlinked decision-support applications contribute to increasing decision-making quality and speed. The applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee3d6108d08281c9189590a350f750b
https://doi.org/10.1007/978-3-030-98062-7_16-1
https://doi.org/10.1007/978-3-030-98062-7_16-1
Publikováno v:
Lecture Notes in Production Engineering ISBN: 9783031183171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb126f5802544dc332e94d772128c1fa
https://doi.org/10.1007/978-3-031-18318-8_55
https://doi.org/10.1007/978-3-031-18318-8_55
Autor:
Michael D. Buschmann, Manuel J. Carrasco, Suman Alishetty, Mikell Paige, Mohamad Gabriel Alameh, Drew Weissman
Publikováno v:
Vaccines, Vol 9, Iss 1, p 65 (2021)
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the development of lipid nanoparticle delivery systems that not only efficiently express the mRNA-encoded immunogen after intramuscular injection, but also play roles
Externí odkaz:
https://doaj.org/article/7520c01c5127460eac7a71be1bad4007
Autor:
Karen D. Gordon, Pierre Savard, Adele Changoor, M. Garon, E. Quenneville, Shelley B. Bull, Mark Hurtig, Michael D. Buschmann
Publikováno v:
Cartilage
Objective We aimed to demonstrate that electroarthrography (EAG) measures streaming potentials originating in the cartilage extracellular matrix during load bearing through electrodes adhered to skin surrounding an articular joint. Design Equine meta
Autor:
Manuel J. Carrasco, Tomaz B. Manzoni, Suman Alishetty, Hooda Said, Paul Bates, Philip Hicks, Thomas E. Cleveland, Farhang Alem, Aarthi Narayanan, Drew Weissman, Ousamah Younoss Soliman, Mikell Paige, Patrick Gillevet, Alexander Grishaev, Keziah Hernandez, Mohamad-Gabriel Alameh, Michael D. Buschmann, Lacey Wright, Alisa Stephens-Shields
Concerns with current mRNA Lipid Nanoparticle (LNP) systems include dose-limiting reactogenicity, adverse events that may be partly due to systemic off target expression of the immunogen, and a very limited understanding of the mechanisms responsible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a3f29d0d19842ce51561cac8844acab
https://doi.org/10.21203/rs.3.rs-798453/v1
https://doi.org/10.21203/rs.3.rs-798453/v1
Publikováno v:
Journal of Biomaterials Applications. 33:792-807
Rotator cuff tears result in shoulder pain, stiffness, weakness and loss of motion. After surgical repair, high failure rates have been reported based on objective imaging and it is recognized that current surgical treatments need improvement. The ai
Autor:
Michael D. Buschmann, Thomas E. Cleveland, Drew Weissman, Hooda Said, Suman Alishetty, Alexander Grishaev, Lacey Wright, Ousamah Younoss Soliman, Manuel J. Carrasco, Mikell Paige, Mohamad-Gabriel Alameh
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Lipid Nanoparticles (LNPs) are used to deliver siRNA and COVID-19 mRNA vaccines. The main factor known to determine their delivery efficiency is the pKa of the LNP containing an ionizable lipid. Herein, we report a method that can predict the LNP pKa
Autor:
Manuel J. Carrasco, Michael D. Buschmann, Mikell Paige, Suman Alishetty, Drew Weissman, Mohamad-Gabriel Alameh
Publikováno v:
Vaccines, Vol 9, Iss 65, p 65 (2021)
Vaccines
Vaccines
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the development of lipid nanoparticle delivery systems that not only efficiently express the mRNA-encoded immunogen after intramuscular injection, but also play roles