Zobrazeno 1 - 10
of 417
pro vyhledávání: '"D. Burkart"'
Autor:
Loles Hoogerland, Stefan Pieter Hendrik van den Berg, Yixing Suo, Yuta W. Moriuchi, Adja Zoumaro-Djayoon, Esther Geurken, Flora Yang, Frank Bruggeman, Michael D. Burkart, Gregory Bokinsky
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract All free-living microorganisms homeostatically maintain the fluidity of their membranes by adapting lipid composition to environmental temperatures. Here, we quantify enzymes and metabolic intermediates of the Escherichia coli fatty acid and
Externí odkaz:
https://doaj.org/article/e815da0745bf4c279554f228a83237fd
Autor:
Marco N. Allemann, Marissa Tessman, Jaysen Reindel, Gordon B. Scofield, Payton Evans, Robert S. Pomeroy, Michael D. Burkart, Stephen P. Mayfield, Ryan Simkovsky
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The accumulation of microplastics in various ecosystems has now been well documented and recent evidence suggests detrimental effects on various biological processes due to this pollution. Accumulation of microplastics in the natural environ
Externí odkaz:
https://doaj.org/article/9e8465f30a4e49718b892f75f0882e46
Autor:
Renee T. Williams, Annika Caspers-Brown, Jennifer Michaud, Natalie Stevens, Michael Meehan, Camille M. Sultana, Christopher Lee, Francesca Malfatti, Yanyan Zhou, Farooq Azam, Kimberly A. Prather, Pieter Dorrestein, Michael D. Burkart, Robert S. Pomeroy
Publikováno v:
Metabolites, Vol 14, Iss 11, p 631 (2024)
Background: Glyoxal has been implicated as a significant contributor to the formation of secondary organic aerosols, which play a key role in our ability to estimate the impact of aerosols on climate. Elevated concentrations of glyoxal over open ocea
Externí odkaz:
https://doaj.org/article/df22652e549441d295d5c3933cee05d0
Autor:
Mária Džunková, James J. La Clair, Tomáš Tyml, Devin Doud, Frederik Schulz, Samuel Piquer-Esteban, Dafne Porcel Sanchis, Andrew Osborn, David Robinson, Katherine B. Louie, Ben P. Bowen, Robert M. Bowers, Janey Lee, Vicente Arnau, Wladimiro Díaz-Villanueva, Ramunas Stepanauskas, Terrence Gosliner, Shailesh V. Date, Trent R. Northen, Jan-Fang Cheng, Michael D. Burkart, Tanja Woyke
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-24 (2023)
Abstract Background Nudibranchs comprise a group of > 6000 marine soft-bodied mollusk species known to use secondary metabolites (natural products) for chemical defense. The full diversity of these metabolites and whether symbiotic microbes are respo
Externí odkaz:
https://doaj.org/article/d885a6b36ed6498aa727710bc46feac4
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 2, Pp 677-688 (2022)
Non-ribosomal peptide synthetases (NRPSs) are attractive targets for biosynthetic pathway engineering due to their modular architecture and the therapeutic relevance of their products. With catalysis mediated by specific protein-protein interactions
Externí odkaz:
https://doaj.org/article/388ffd2bdbb74001847a74c21c99f500
Autor:
Saranshu Singla, K. Zin Htut, Runyao Zhu, Amara Davis, Jiayang Ma, Qing Zhe Ni, Michael D. Burkart, Christopher Maurer, Toshikazu Miyoshi, Ali Dhinojwala
Publikováno v:
ACS Omega, Vol 6, Iss 51, Pp 35514-35522 (2021)
Externí odkaz:
https://doaj.org/article/87dbed94632b4d58b9504f1dac3afe32
Autor:
C. M. Beall, J. M. Michaud, M. A. Fish, J. Dinasquet, G. C. Cornwell, M. D. Stokes, M. D. Burkart, T. C. Hill, P. J. DeMott, K. A. Prather
Publikováno v:
Atmospheric Chemistry and Physics, Vol 21, Pp 9031-9045 (2021)
Ice-nucleating particles (INPs) represent a rare subset of aerosol particles that initiate cloud droplet freezing at temperatures above the homogenous freezing point of water (−38 ∘C). Considering that the ocean covers 71 % of the Earth's surface
Externí odkaz:
https://doaj.org/article/a33c875a02a244d9a2c09742f50c8cce
Autor:
Thomas G. Bartholow, Terra Sztain, Ashay Patel, D. John Lee, Megan A. Young, Ruben Abagyan, Michael D. Burkart
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Using structural and computational analysis, Bartholow et al. perform a comprehensive residue-by-residue comparison of the protein-protein interactions in de novo fatty acid biosynthesis that occurs in E. coli. This study provides insights into molec
Externí odkaz:
https://doaj.org/article/93abe143c4514ee6b3184a5151b517f0
Autor:
Jeffrey T. Mindrebo, Ashay Patel, Woojoo E. Kim, Tony D. Davis, Aochiu Chen, Thomas G. Bartholow, James J. La Clair, J. Andrew McCammon, Joseph P. Noel, Michael D. Burkart
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The formation of C-C bonds in fatty acid and polyketide biosynthesis depends on β-ketoacyl-acyl carrier protein (ACP) synthases (KSs). Here, the authors present structures of E.coli KSs bound to substrate mimetic bearing ACPs, providing insights int
Externí odkaz:
https://doaj.org/article/8b2f324577e8467b8bb69a969b0ffd83
Publikováno v:
Molecules, Vol 27, Iss 15, p 4885 (2022)
To realize the commercialization of sustainable materials, new polymers must be generated and systematically evaluated for material characteristics and end-of-life treatment. Polyester polyols made from renewable monomers have found limited adoption
Externí odkaz:
https://doaj.org/article/e00677d104314526b7c2a5042465169b