Zobrazeno 1 - 10
of 163
pro vyhledávání: '"D. Bernuau"'
Autor:
Franck Verrecchia, D. Bernuau, Agnès Legrand, Niclas Setterblad, Jocelyne André, Alain Mauviel, Fanny Daniel, Meryem C. Güller
Publikováno v:
Molecular Carcinogenesis. 48:532-544
Transforming growth factor beta (TGF-beta) exerts an important role in the late steps of carcinogenesis by cooperating with Ras to induce cell motility and tumor invasion. The transcription complex AP-1 has been implicated in the regulation of genes
Publikováno v:
Oncogene. 20:5132-5142
AP-1 and NF-kappaB are rapidly activated during liver regeneration. Whether these parallel inductions have potential functional implications is not known. Isolated rat hepatocytes were stimulated with two mitogens, epidermal growth factor or hepatocy
Publikováno v:
Analytical Biochemistry. 232:225-230
The sensitivity of direct solution hybridization of hepatocytes solubilized in guanidium thiocyanate (GuSCN) for detecting alpha 1-acid glycoprotein and albumin mRNAs was studied. The sensitivity of detection was inversely correlated with the DNA con
Autor:
Mauriz Jl, Meryem C. Güller, Toualbi K, C Labalette, D. Bernuau, Marie-Annick Buendia, Alain Mauviel
Publikováno v:
Oncogene. 26(24)
Stabilization of cytoplasmic beta-catenin is a hallmark of a variety of cancers. The stabilized beta-catenin is able to translocate to the nucleus, where it acts as a transcriptional activator of T-cell factor (TCF)-regulated genes. beta-Catenin may
Publikováno v:
The Journal of biological chemistry. 276(13)
Cross-talk between Smad and mitogen-activated protein kinase pathways has been described recently, and evidence for Smad cooperation with AP-1 is emerging. Here we report that epidermal growth factor (EGF) potentializes transforming growth factor bet
Publikováno v:
Journal of hepatology. 30(5)
Background/Aims: Stimulation of activator protein-1 (AP-1), a Fos/Jun complex, is a key event in the cell response to growth factors. We have investigated whether hepatocyte growth factor (HGF) induces differential AP-1 responses in normal and transf
Publikováno v:
Journal of Hepatology. 48:S130-S131
Publikováno v:
Hepatology (Baltimore, Md.). 26(6)
Activation of the transcriptional regulator AP-1, a dimeric complex formed of various combinations of Fos and Jun proteins, is a key step in the cellular response to mitogens. Because different dimers are believed to display different regulatory func
Autor:
Lorraine Racine-Samson, D. Bernuau, Jean-Yves Scoazec, Alain Moreau, Laurence Christa, Gérard Feldmann
Publikováno v:
Histochemistry and cell biology. 105(4)
The coexpression of normally periportal and perivenous markers has been described in heterotopically transplanted hepatocytes. To determine whether such a coexpression might also occur in hepatocytes retaining their original intrahepatic location, we
Publikováno v:
Journal of hepatology. 21(6)
Activation of cellular oncogenes and inactivation of anti-oncogenes have been postulated as important mechanisms during hepatocarcinogenesis. This study was conducted to detect abnormal levels of several proto-oncogenes (c-jun, c-fos, c-H-ras) and of