Zobrazeno 1 - 10
of 155
pro vyhledávání: '"D. B. Webster"'
Autor:
K Nistala, C Meaney, Hubert B. Gaspar, E G Davies, Alison Jones, Kimberly Gilmour, Z. Sherrell, Helen Chapel, David Eastwood, A. D. B. Webster
SUMMARY The molecular basis of common variable immunodeficiency (CVID) is undefined, and diagnosis requires exclusion of other diseases including X-linked lymphoproliferative disease (XLP). This rare disorder of immunedysregulation presents typically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2bad9d26d4253e3ee0f3c094053d2e
https://ora.ox.ac.uk/objects/uuid:9f5bf628-6213-4dab-b425-13e597df6836
https://ora.ox.ac.uk/objects/uuid:9f5bf628-6213-4dab-b425-13e597df6836
Publikováno v:
Clinical and Experimental Immunology. 145:420-427
Summary Monocyte-derived dendritic cells (MdDCs) from many patients with common variable immunodeficiency (CVID) have been shown recently to have reduced expression of surface molecules associated with maturity. Using flow cytometry and confocal micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d985f18ff7f00273c649895887cd127
https://doi.org/10.1111/j.1365-2249.2006.03152.x
https://doi.org/10.1111/j.1365-2249.2006.03152.x
Autor:
Bodo Grimbacher, Annette Schmitt-Graeff, A. D. B. Webster, Qiang Pan-Hammarström, Michael Schlesier, Jürgen K. Rockstroh, Ulrich Salzer, Pascal Schneider, Lennart Hammarström, Hans-Hartmut Peter, Alejandro A. Schäffer, Helen Chapel
Publikováno v:
Nature Genetics, vol. 37, no. 8, pp. 820-828
The functional interaction of BAFF and APRIL with TNF receptor superfamily members BAFFR, TACI and BCMA is crucial for development and maintenance of humoral immunity in mice and humans. Using a candidate gene approach, we identified homozygous and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042c023982477131bc66639caf3e4f71
https://doi.org/10.1038/ng1600
https://doi.org/10.1038/ng1600
Publikováno v:
Clinical and Experimental Immunology. 134:321-327
SUMMARY We investigated the expression of T helper (Th)1/Th2 regulatory cytokine receptors on lymphocytes from patients with common variable immunodeficiency (CVID), a disorder associated with raised Th1 cytokine production, comparing the results wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441401be26fa99ab241ab69a7dc07562
https://doi.org/10.1046/j.1365-2249.2003.02271.x
https://doi.org/10.1046/j.1365-2249.2003.02271.x
Autor:
M D Bodman-Smith, Maria J. Leandro, Jonathan C. W. Edwards, Anthony D B Webster, Michael R. Ehrenstein, Geraldine Cambridge, Martin Salden
Publikováno v:
Arthritis & Rheumatism. 48:2146-2154
Objective To explore the changes in serologic variables and clinical disease activity following B lymphocyte depletion in 22 patients with rheumatoid arthritis (RA). Methods B lymphocyte depletion was attained using combination therapy based on the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3290d139b4055eb1078655f0cbbc53
https://doi.org/10.1002/art.11181
https://doi.org/10.1002/art.11181
Autor:
Madrigal A, Lars Hammarström, Steven G.E. Marsh, Jana Kralovicova, Igor Vorechovsky, Laycock, A. D. B. Webster
Publikováno v:
European Journal of Human Genetics. 9:590-598
We present a dense STR/linkage disequilibrium(LD)/gene map between the RING3 and HLA-B loci, reference allelic sizes on the most prevalent HLA haplotypes and their allelic frequencies in pedigree founders. This resource will facilitate LD, evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75d1c49fd6c2a5a71ed708efcbadb8b
https://doi.org/10.1038/sj.ejhg.5200688
https://doi.org/10.1038/sj.ejhg.5200688
Publikováno v:
Computers & Industrial Engineering. 40:101-116
This paper compares the total inventory costs (TIC) of five lot-sizing techniques. The add-drop heuristic (ADH) is a capacitated technique and the lot-for-lot (L4L), fixed period quantity (FPQ), least unit cost (LUC) and the silver-meal heuristic (SM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e44177f6cf1c6df91392a8389c478fbf
https://doi.org/10.1016/s0360-8352(00)00079-6
https://doi.org/10.1016/s0360-8352(00)00079-6
Publikováno v:
Clinical and Experimental Immunology. 121:506-514
SUMMARYAbsolute and relative NK cell numbers were determined in peripheral whole blood by flow cytometry in patients with common variable immunodeficiency (CVID) (n = 55) and X-linked agammaglobulinaemia (XLA) (n = 19) on regular immunoglobulin (IVIG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adab4590608d8dfde5d4b93c949dc9b
https://doi.org/10.1046/j.1365-2249.2000.01317.x
https://doi.org/10.1046/j.1365-2249.2000.01317.x
Publikováno v:
Clinical and Experimental Immunology. 116:509-515
We examined the effects of intravenous immunoglobulin (IVIG) on cytokine regulation in vivo using samples taken before and after replacement-dose (200–400 mg/kg) IVIG in a group of patients with common variable immunodeficiency (CVID) and X-linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259fa020dba46eb6030fec35c03c7835
https://doi.org/10.1046/j.1365-2249.1999.00924.x
https://doi.org/10.1046/j.1365-2249.1999.00924.x
Publikováno v:
British Journal of Dermatology. 138:1053-1057
Hyper-IgM (HIM) syndrome is a rare primary immunodeficiency disorder. Approximately 120 cases have been described in the literature world-wide. Features of HIM include low serum IgG, a very low IgA with normal or high IgM levels. Autoimmune phenomena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bfd3cae13448df8fecf3abc9039629
https://doi.org/10.1046/j.1365-2133.1998.02278.x
https://doi.org/10.1046/j.1365-2133.1998.02278.x