A Single Sub-anesthetic Dose of Ketamine Relieves Depression-like Behaviors Induced by Neuropathic Pain in Rats

Autor: Jing Wang, Edward B. Ziff, Sarah E. Eberle, Duo Xu, David S. Tukey, D. B. Shamir, Yossef Goffer, Thomas J. J. Blanck, Anthony Zou

Background Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cebc9d736698aa614cf69745739f43
https://europepmc.org/articles/PMC3222930/

Systemic Administration of Neurotransmitter-Derived Lipidoids-PROTACs-DNA Nanocomplex Promotes Tau Clearance and Cognitive Recovery for Alzheimer's Disease Therapy.

Autor: Gong B; Department of Neurology, Second Affiliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Shanghai, 200003, China., Zhang W; School of Pharmacy, University College London, London, WC1N 1AX, UK., Cong W; School of Medicine, Shanghai University, Shanghai, 200444, China., Gu Y; Department of Neurology, Second Affiliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Shanghai, 200003, China., Ji W; Department of Neurology, Second Affiliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Shanghai, 200003, China., Yin T; Department of Neurology, Second Affiliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Shanghai, 200003, China., Zhou H; Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China., Hu H; School of Medicine, Shanghai University, Shanghai, 200444, China., Zhuang J; Department of Neurology, Second Affiliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Shanghai, 200003, China., Luo Y; New Drug Discovery and Development, Biotheus Inc., Zhuhai, 519080, China.; Clinical Pharmacy Innovation Institute, Shanghai Jiao Tong University of Medicine, Shanghai, 200240, China., Liu Y; Clinical Pharmacy Innovation Institute, Shanghai Jiao Tong University of Medicine, Shanghai, 200240, China.; Department of Clinical Pharmacy, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China., Gao J; Changhai Clinical Research Unit, Shanghai Changhai Hospital, Naval Medical University, Shanghai, 200433, China., Yin Y; Department of Neurology, Second Affiliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Shanghai, 200003, China.; Department of Neurology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, China.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Jul 15, pp. e2400149. Date of Electronic Publication: 2024 Jul 15.