Zobrazeno 1 - 10
of 42
pro vyhledávání: '"D. B. Rifkin"'
Autor:
C. Bellini, M. R. Bersi, A. W. Caulk, J. Ferruzzi, D. M. Milewicz, F. Ramirez, D. B. Rifkin, G. Tellides, H. Yanagisawa, J. D. Humphrey
Supplemental Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09de9dc8425de1a6d52db4b22b79c961
Publikováno v:
Development. 121:4383-4393
To determine whether fibroblast growth factor (FGF) has a role in lens development, we have generated transgenic mice expressing a dominant-negative form of the murine FGF receptor-1 (FGFRDN) in the lens. Using the fibre cell- specific αA-crystallin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae9000ca49c0d8d72a38680df7f98d9
https://doi.org/10.1242/dev.121.12.4383
https://doi.org/10.1242/dev.121.12.4383
Publikováno v:
The Journal of Immunology. 155:1450-1459
Transforming growth factor-beta (TGF-beta) is secreted by most cells as a biologically inactive complex, called the large latent TGF-beta complex. The complex is comprised of latent TGF-beta binding protein (LTBP) and latent TGF-beta, which is mature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbec339c10c46c18ecc5b2ae3b4c32e2
https://doi.org/10.4049/jimmunol.155.3.1450
https://doi.org/10.4049/jimmunol.155.3.1450
Autor:
P, Mignatti, D B, Rifkin
Publikováno v:
Advances in cancer research. 78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5c137bc9606ed7ddf925ed708414e38
https://pubmed.ncbi.nlm.nih.gov/10547669
https://pubmed.ncbi.nlm.nih.gov/10547669
Autor:
O G, Wilhelm, S, Wilhelm, G M, Escott, V, Lutz, V, Magdolen, M, Schmitt, D B, Rifkin, E L, Wilson, H, Graeff, G, Brunner
Publikováno v:
Journal of cellular physiology. 180(2)
The glycosylphosphatidylinositol (GPI)-anchored, multifunctional receptor for the serine proteinase, urokinase plasminogen activator (uPAR, CD87), regulates plasminogen activation and cell migration, adhesion, and proliferation. uPAR occurs in functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4390d6eb9ed21333415c3df1ca1e9c42
https://pubmed.ncbi.nlm.nih.gov/10395292
https://pubmed.ncbi.nlm.nih.gov/10395292
Autor:
P E, Gleizes, D B, Rifkin
Publikováno v:
Pathologie-biologie. 47(4)
Recent molecular genetics studies in humans and mice showed that transforming growth factor-beta (TGF-beta) is involved in vasculogenesis and maintenance of blood vessel integrity. These results confirm earlier in vitro studies demonstrating generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46618e941f7dd93016d79f3d1da939a6
https://pubmed.ncbi.nlm.nih.gov/10372400
https://pubmed.ncbi.nlm.nih.gov/10372400
Autor:
J S, Munger, X, Huang, H, Kawakatsu, M J, Griffiths, S L, Dalton, J, Wu, J F, Pittet, N, Kaminski, C, Garat, M A, Matthay, D B, Rifkin, D, Sheppard
Publikováno v:
Cell. 96(3)
Transforming growth factor beta (TGF beta) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGF beta gene product. Extracellular activation of these complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccfb4cf2123fa1959116b05830bad14a
https://pubmed.ncbi.nlm.nih.gov/10025398
https://pubmed.ncbi.nlm.nih.gov/10025398
Publikováno v:
The American journal of pathology. 150(1)
Urokinase-type plasminogen activator (uPA) is thought to be an important mediator in the proteolytic degradation of extracellular matrix components observed in a wide variety of normal physiological and pathological conditions. However, the phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d55adcce8f6ae6eb7295d3f6094c780e
https://pubmed.ncbi.nlm.nih.gov/9006351
https://pubmed.ncbi.nlm.nih.gov/9006351
Publikováno v:
Anticancer research. 16(5A)
A number of proteins are found attached to the plasma membrane of mammalian cells by a glycosylphosphatidylinositol (GPI) anchor that can be cleaved by GPI specific phospholipase D (GPI-PLD). There are no known specific inhibitors of GPI-PLD. We exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b14171a6b13b5cdb7897386558ca093
https://pubmed.ncbi.nlm.nih.gov/8917344
https://pubmed.ncbi.nlm.nih.gov/8917344
Autor:
R L, Shapiro, J G, Duquette, D F, Roses, I, Nunes, M N, Harris, H, Kamino, E L, Wilson, D B, Rifkin
Publikováno v:
Cancer research. 56(15)
Evidence suggests that the plasminogen activators (PAs), in particular urokinase-type PA (uPA), play a pivotal role in tumor invasion and metastasis. We studied the contribution of the PAs to the malignant phenotype through the chemical induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf404a1e5426ca72369ceedf1476d302
https://pubmed.ncbi.nlm.nih.gov/8758932
https://pubmed.ncbi.nlm.nih.gov/8758932