Zobrazeno 1 - 2
of 2
pro vyhledávání: '"D. B. Prince"'
Autor:
A. Tomasselli, D. Paddock, T. Emmons, A. Mildner, J. Leone, J. Lull, J. Cialdella, D. Prince, H. Fischer, R. Heinrikson, T. Benson, A. G. Tomasselli, D. J. Paddock, T. L. Emmons, A. M. Mildner, J. W. Leone, J. M. Lull, J. I. Cialdella, D. B. Prince, H. D. Fischer, R. L. Heinrikson, T. E. Benson
Publikováno v:
Protein & Peptide Letters. 15:131-143
BACE (beta-site APP cleaving enzyme) or beta-secretase, the enzyme responsible for processing APP to give the N-terminal portion of the Abeta peptide, is a membrane bound aspartyl protease consisting of an ectodomain catalytic unit, a C-terminal tran
Autor:
A. Tomasselli, T. Emmons, M. Shuck, M. Babcock, J. Holloway, J. Leone, J. Durbin, D. Paddock, D. Prince, R. Heinrikson, H. Fischer, M. Bienkowski, T. Benson, T. L. Emmons, M. E. Shuck, M. S. Babcock, J. S. Holloway, J. W. Leone, J. D. Durbin, D. J. Paddock, D. B. Prince, R. L. Heinrikson, H. D. Fischer, M. J. Bienkowski, T. E. Benson, A. G. Tomasselli
Publikováno v:
Protein and peptide letters. 15(2)
BACE, or beta-secretase, is an attractive target in the treatment of Alzheimer's Disease because of its involvement in the generation of amyloid beta peptides. BACE is a type I transmembrane aspartyl protease composed of pre-, pro-, catalytic, transm