Zobrazeno 1 - 4
of 4
pro vyhledávání: '"D. B. Longley"'
Autor:
P. Smyth, L. Ferguson, J. F. Burrows, R. E. Burden, S. R. Tracey, Ú. M. Herron, M. Kovaleva, R. Williams, A. J. Porter, D. B. Longley, C. J. Barelle, C. J. Scott
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Aberrant activity of the cysteine protease Cathepsin S (CTSS) has been implicated across a wide range of pathologies. Notably in cancer, CTSS has been shown to promote tumour progression, primarily through facilitating invasion and migration of tumou
Externí odkaz:
https://doaj.org/article/c73d1a2f27044702b9125d5d2cae26d0
Autor:
W L, Allen, P D, Dunne, S, McDade, E, Scanlon, M, Loughrey, H, Coleman, C, McCann, K, McLaughlin, Z, Nemeth, N, Syed, P, Jithesh, K, Arthur, R, Wilson, V, Coyle, D, McArt, G I, Murray, L, Samuel, P, Nuciforo, J, Jimenez, G, Argiles, R, Dienstmann, J, Tabernero, L, Messerini, S, Nobili, E, Mini, K, Sheahan, E, Ryan, P G, Johnston, S, Van Schaeybroeck, M, Lawler, D B, Longley
Transcriptomic profiling of colorectal cancer (CRC) has led to identification of four consensus molecular subtypes (CMS1-4), which have prognostic value in stage II/III disease. More recently, the Colorectal Cancer Intrinsic Subtypes (CRIS) classific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9141b5bd3c825b310e2851e50702c8ff
https://europepmc.org/articles/PMC6040635/
https://europepmc.org/articles/PMC6040635/
Autor:
D B, Longley, P R, Ferguson, J, Boyer, T, Latif, M, Lynch, P, Maxwell, D P, Harkin, P G, Johnston
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(11)
Thymidylate synthase (TS) is responsible for the de novo synthesis of thymidylate, which is required for DNA synthesis and repair and which is an important target for fluoropyrimidines such as 5-fluorouracil (5-FU), and antifolates such as Tomudex (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4684b8bc7bd3a9cb722d420a931229f6
https://pubmed.ncbi.nlm.nih.gov/11705873
https://pubmed.ncbi.nlm.nih.gov/11705873
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(8)
Human acute-phase serum amyloid A protein (A-SAA) is a major acute phase reactant, the concentration of which increases dramatically as part of the body's early response to inflammation. A-SAA is the product of two almost identical genes, SAA1 and SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bdbe470bb5de3724039412db7c75c01
https://pubmed.ncbi.nlm.nih.gov/10510397
https://pubmed.ncbi.nlm.nih.gov/10510397