Zobrazeno 1 - 10
of 61
pro vyhledávání: '"D. B. Lacy"'
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 26:42-50
Compared with untreated dogs, normal dogs treated for 7 days with cyclosporine A and prednisone exhibited a 25% reduction in the absorption of glucose from a mixed meal and a 4- to 5-fold increase in net hepatic glucose uptake, without reduction of p
Autor:
E E Stone, Phillip E. Williams, D. B. Lacy, David H. Wasserman, Robert H. Coker, Yoshiharu Koyama, Kareem Jabbour
Publikováno v:
Diabetes. 49:1434-1442
The carotid bodies are sensitive to glucose in vitro and can be stimulated to cause hyperglycemia in vivo. The aim of this study was to determine if the carotid bodies are involved in basal glucoregulation or the counterregulatory response to an insu
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 24:244-250
BACKGROUND Combination immunosuppressive therapy, that often includes prednisone and cyclosporine A (CyA), is commonly used in the treatment of organ transplant patients. We hypothesized that CyA and prednisone treatment would alter the roles of the
Autor:
D. B. Lacy, Yoshiharu Koyama, Alan D. Cherrington, Pietro Galassetti, David H. Wasserman, Robert H. Coker
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 277:E1038-E1045
Prior exercise stimulates muscle and liver glucose uptake. A negative arterial-portal venous glucose gradient (a-pv grad) stimulates resting net hepatic glucose uptake (NHGU) but reduces muscle glucose uptake. This study investigates the effects of a
Autor:
Raymond C. Stevens, D B Lacy
Publikováno v:
Journal of Molecular Biology. 291:1091-1104
The clostridial neurotoxins (CNTs), comprised of tetanus neurotoxin (TeNT) and the seven serotypes of botulinum neurotoxin (BoNT A-G), specifically bind to neuronal cells and disrupt neurotransmitter release by cleaving proteins involved in synaptic
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 276:E1022-E1029
The aim of these studies was to determine whether prior exercise enhances net hepatic glucose uptake (NHGU) during a glucose load. Sampling catheters (carotid artery, portal, hepatic, and iliac veins), infusion catheters (portal vein and vena cava),
Autor:
David H. Wasserman, D. B. Lacy, Katherine S. Hamilton, Deanna P. Bracy, Pietro Galassetti, Alan D. Cherrington, Fiona K. Gibbons
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 276:E543-E552
The effects of prior fast duration (18 h, n = 8; 42 h, n = 8) on the glycemic and tissue-specific responses to an intraduodenal glucose load were studied in chronically catheterized conscious dogs. [3-3H]glucose was infused throughout the study. Afte
Autor:
Fiona K. Gibbons, David H. Wasserman, Katherine S. Hamilton, Pietro Galassetti, D. B. Lacy, Alan D. Cherrington
Publikováno v:
Journal of Applied Physiology. 84:1952-1959
The hypothesis that glucose ingestion in the postexercise state enhances the synthesis of glutamine and alanine in the skeletal muscle was tested. Glucose was infused intraduodenally for 150 min (44.5 μmol ⋅ kg−1⋅ min−1) beginning 30 min aft
Autor:
Raymond C. Stevens, D B Lacy
Publikováno v:
Protein Expression and Purification. 11:195-200
Botulinum neurotoxin type A in its fully activated form exists as a dichain protein consisting of a 50-kDa light chain and a 100-kDa heavy chain linked by a disulfide bond (B. R. DasGupta and H. Sugiyama, Biochem. Biophys. Res. Commun. 48, 108-112, 1
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 272:E530-E542
Hyperinsulinemic euglycemic and hypoglycemic clamps were used to study the interaction of exercise, insulin, and hypoglycemia at rest and during exercise in the dog. Sampling (artery and portal, hepatic, and iliac veins) and infusion (vena cava) cath