Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D. B. Kazanskii"'
Autor:
D. B. Kazanskii
Publikováno v:
Медицинская иммунология, Vol 7, Iss 5–6, Pp 477-488 (2014)
Abstract. The MHC molecules are the strongest transplantational antigens determining direct intraction with 95-98% of T cell clones activating in response to allograft. Interaction with MHC molecules is critically important for positive selection of
Externí odkaz:
https://doaj.org/article/ef73267ca11e4b899784a4ac627f984e
Publikováno v:
Doklady Biological Sciences. 413:172-175
172 Cytotoxic T-lymphocytes (CTLs) are the main cytotoxic effector cells of the immune system. Cytotoxic Tlymphocytes are able to control homeostasis by recognizing and eliminating the cells that were infected or underwent mutation or malignization.
Autor:
Elena L Pobezinskaya, I. A. Baturina, D. B. Kazanskii, T. S. Grinenko, L. A. Pobezinskii, Ekaterina Zvezdova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 140:545-549
Immune response to allogenic tumor cells is associated with the appearance of long-living CD8+ memory cells capable of rapid restimulation and lysis of tumor cells in case of repeated injection of these cells. In order to acquire the effector functio
Autor:
Elena L Pobezinskaya, T. S. Tereshchenko, Ekaterina Zvezdova, T. V. Anfalova, Yu. Yu. Silaeva, L. M. Khromykh, L. A. Pobezinskii, D. B. Kazanskii
Publikováno v:
Bulletin of Experimental Biology and Medicine. 137:493-498
Experiments on mice deficient in expression of class I major histocompatibility complex molecules showed that memory CD8+ cells recognizing the alloantigen by the direct allogeneic recognition mechanism selectively proliferated in response to heated
Publikováno v:
Bulletin of Experimental Biology and Medicine. 136:314-317
We propose a new colorimetric method for evaluation of specific T lymphocyte cytotoxicity based on the capacity of viable cells to incorporate alamar blue dye, an indicator of cell metabolic activity. This method is effective for highly specific stra
Publikováno v:
Russian Journal of Developmental Biology. 34:223-231
The data presented demonstrate the capacity of allospecific cytotoxic lymphocytes to fulfill noncytolytic regulatory functions. Cytotoxic lymphocytes suppress cell proliferation induced during development of a response in reactions of a mixed culture
Publikováno v:
Russian Journal of Developmental Biology. 33:65-69
It was shown using complement-dependent cytolysis and monoclonal antibodies against CD4, CD8, and NK1.1 antigens that the cortisone-resistant CD3+4–8–NK1.1–-thymocytes spontaneously secreted a chemotactic transmitter inducing the release and di
Publikováno v:
Doklady Biological Sciences. 388:89-91
Cytotoxic T lymphocytes (CTLs) are the main effector cells in viral infections, tumor growth, and rejection of tissue grafts. Specific T killers maintain homeostasis within the body by recognizing and eliminating self cells that have undergone mutati
Autor:
T. V. Vasil’eva, Ekaterina Zvezdova, T. V. Anfalova, T. S. Grinenko, L. M. Khromykh, Elena L Pobezinskaya, V. N. Petrishchev, I. A. Baturina, D. B. Kazanskii, L. A. Pobezinskii
Publikováno v:
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 402
Publikováno v:
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 388