Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D. B. Hill"'
Publikováno v:
Journal of Clinical Investigation. 94:2209-2214
In experimental animals, injection of gram-negative endotoxin (LPS) decreases hepatic cytochrome P450-mediated drug metabolism. To evaluate this phenomenon in a human model of gram-negative sepsis, LPS was administered on two consecutive days to heal
Autor:
D B, Hill
Publikováno v:
Family practice management. 8(7)
Autor:
I V, Deaciuc, N B, D'Souza, W J, de Villiers, R, Burikhanov, T G, Sarphie, D B, Hill, C J, McClain
Publikováno v:
Alcoholism, clinical and experimental research. 25(6)
The mechanisms of liver sensitization by alcohol to Gram-negative bacterial lipopolysaccharide (LPS) remain elusive. The purpose of this study was two-fold: (1) to test the hypothesis that alcohol-enhanced liver apoptosis may be a sensitizing mechani
Publikováno v:
Alcoholism, clinical and experimental research. 24(10)
The role of apoptosis in EtOH-induced liver injury has not been investigated much. Therefore, the question whether apoptosis is a contributory factor to alcoholic liver disease remains to be answered. The purpose of this study was to characterize the
Autor:
A F, Jerant, D B, Hill
Publikováno v:
The Journal of family practice. 49(4)
We reviewed the evidence regarding the effectiveness of electronic medical records (EMRs) as tools for improving surrogate patient outcomes in the outpatient primary care setting.We searched the MEDLINE database (1966-1999) to find relevant articles
Publikováno v:
Alcoholism, clinical and experimental research. 23(2)
The purpose of this study was to determine if exacerbation of apoptosis precedes liver injury during chronic exposure of rats to alcohol. After 7 weeks of feeding an alcohol- or dextrin-containing liquid diet, the animals were treated with gram-negat
Publikováno v:
The International journal of eating disorders. 25(1)
Eating disorder patients frequently present with gastrointestinal complaints. Helicobacter pylori is an etiologic factor in type B gastritis, gastric and duodenal ulcers, and may cause nausea and anorexia.To determine whether or not there is an incre
Publikováno v:
Alcoholism, clinical and experimental research. 22(6)
The purpose of this study was to evaluate the role of the sinusoidal endothelial cell (SEC) during the clinical course of alcoholic hepatitis. Twenty consenting patients (mean age: 49.4 +/- 11.0 years) with moderate or severe hepatitis were studied.
Publikováno v:
Alcohol Health and Research World
Chemical messengers called cytokines play an important role during the body’s initial response to infection (i.e., acute inflammation). Cytokines attract and activate components of the immune system, promote blood clotting, and facilitate the relea
Publikováno v:
Hepatology (Baltimore, Md.). 21(4)
Tumor necrosis factor-alpha (TNF-alpha) is a mediator of liver injury. The objective of this study was to develop an in vitro model of TNF-mediated liver cell injury using the Hep G2 cell line. Hep G2 cells normally are insensitive to TNF cytotoxicit