Zobrazeno 1 - 10
of 57
pro vyhledávání: '"D. B. Bylund"'
Autor:
D. B. Bylund, Jodi Polaha, Shelley D. Smith, Christopher J. Kratochvil, Carol Ellis, J. D. Deupree, D. Bohac
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :877-884
Neuropharmacological and genetic association studies have implicated norepinephrine and adrenergic receptors in the pathogenesis of ADHD. The purpose of this study was to compare genetic association studies of three polymorphisms of the alpha-2A adre
Autor:
D. B. Bylund, L. L. Brockunier, D. V. Pratt, L. V. Kudzma, S. Harris, R. A. Del Vecchio, C. R. Pandit, Thomas P. Jerussi, J. R. Bagley, A. Galdes
Publikováno v:
ChemInform. 26
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(1)
Mice with altered alpha(2)-adrenergic receptor genes have become important tools in elucidating the subtype-specific functions of the three alpha(2)-adrenergic receptor subtypes because of the lack of sufficiently subtype-selective pharmacological ag
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 126
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 126
Autor:
D B, Bylund, D M, Chacko
Publikováno v:
Investigative ophthalmologyvisual science. 40(10)
To determine the predominant alpha2 adrenergic receptor subtypes present in the human eye.Saturation- and competition-receptor- binding experiments were performed with the radioligand [3H]RX821002 in human ciliary body, retinal pigmented epithelium-c
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(3)
During postnatal development, alpha-2 adrenergic receptors (A2AR) change in both density and distribution. In forebrain, receptor density increases about 4-fold over neonatal levels, reaching adult levels before postnatal day (P) 28, whereas in hindb
Autor:
D A, Heck, D B, Bylund
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(3)
Long-term exposure to agonist down-regulates receptor expression for many G protein-coupled receptors. This decrease in receptor density could occur through either an increase in receptor degradation or a decrease in receptor synthesis. We studied th
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(3)
The alpha-2 adrenergic receptors are known to be present in the mammalian eye and to mediate the effects of alpha-2 agonists used in the treatment of glaucoma. Little is known, however, regarding the relative densities of the three alpha-2 subtypes i
Autor:
Q H, Chen, D B, Bylund
Publikováno v:
Receptorssignal transduction. 7(2)
In the usual formulation of the equations for competitive binding assays, the free concentrations of the various unlabeled ligands are approximated by the known values of their total concentrations, since the free concentrations are not easily determ