Zobrazeno 1 - 10
of 323
pro vyhledávání: '"D. Atkin"'
Autor:
Nadine Michel, Heather M. Raimer Young, Naomi D. Atkin, Umar Arshad, Reem Al-Humadi, Sandeep Singh, Arkadi Manukyan, Lana Gore, Ian E. Burbulis, Yuh-Hwa Wang, Michael J. McConnell
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Neurons are overproduced during cerebral cortical development. Neural progenitor cells (NPCs) divide rapidly and incur frequent DNA double-strand breaks (DSBs) throughout cortical neurogenesis. Although half of the neurons born during neurod
Externí odkaz:
https://doaj.org/article/afbddd025bee472c8522a305ded18559
Autor:
J. Menge, J. Morse, D. Hare, C. Coggins, J. Pehrson, J. Meyer, T. Embleton, S. Van Gundy, A. Dodds, M. L. Arpaia, E. Takele, C. Adams, A. Strawn, E. Pond, D. Atkin
Publikováno v:
California Agriculture, Vol 44, Iss 5, Pp 11-11 (1990)
The McKellar project is a large scale, multidisciplinary effort involving irrigation, nitrogen fertilization, fungicides, nematicides, miticides, and gibberellin treatments. The project, now in its seventh and final year, wlll show which treatments
Externí odkaz:
https://doaj.org/article/0814418ba9574dda972418327b9fd8b5
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the death of both upper and lower motor neurons (MNs) in the brain, brainstem and spinal cord. The neurodegenerative mechanisms leading to MN loss in ALS are not full
Externí odkaz:
https://doaj.org/article/68ee97c8f3a84365bff3f2e52e09a557
Publikováno v:
Translational Neurodegeneration. 12
Redox homeostasis refers to the balance between the production of reactive oxygen species (ROS) as well as reactive nitrogen species (RNS), and their elimination by antioxidants. It is linked to all important cellular activities and oxidative stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83fc6cbdc3bc03a5bbaf45816e96e75b
https://doi.org/10.1186/s40035-023-00350-4
https://doi.org/10.1186/s40035-023-00350-4
Publikováno v:
Genes, Chromosomes and Cancer. 60:808-821
An initiating DNA double strand break (DSB) event precedes the formation of cancer-driven chromosomal abnormalities, such as gene rearrangements. Therefore, measuring DNA breaks at rearrangement-participating regions can provide a unique tool to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f459713c343ef04ad269d6e706e283
https://doi.org/10.1002/gcc.22993
https://doi.org/10.1002/gcc.22993
Autor:
Julie D. Atkin, Sonam Parakh
Publikováno v:
Seminars in Cell & Developmental Biology. 112:105-113
The endoplasmic reticulum (ER) and mitochondria connect at multiple contact sites to form a unique cellular compartment, termed the 'mitochondria-associated ER membranes' (MAMs). MAMs are hubs for signalling pathways that regulate cellular homeostasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f874d8d4848e4b986d83d6ecfb6292c
https://doi.org/10.1016/j.semcdb.2021.02.002
https://doi.org/10.1016/j.semcdb.2021.02.002
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Alison Cheong, Sonam Parakh, Sina Shadfar, Prachi Mehta, Shu Yang, Anand K. Deva, Anna Konopka, Natalie Grima, Adam K. Walker, Cyril J. Jagaraj, Emma R. Perri, Suzanne M. Cutts, Tina Robinson, Garth A. Nicholson, Hamideh Shahheydari, Reka P. Toth, Shafi Jamali, Julie D. Atkin, Audrey Ragagnin, Ian P. Blair, Toby D. M. Bell, Zuzana Horejsi, Marta Vidal, Ivan Khizhnyak, Donna R. Whelan, Jasmin Galper
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-28 (2020)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Pathological forms of TAR DNA-binding protein 43 (TDP-43) are present in motor neurons of almost all amyotrophic lateral sclerosis (ALS) patients, and mutations in TDP-43 are also present in ALS. Loss and gain of TDP-43 functions are impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1571ac2e421081930780f50d6d1b402b
http://link.springer.com/article/10.1186/s13024-020-00386-4
http://link.springer.com/article/10.1186/s13024-020-00386-4
Autor:
Marianne Hallupp, Colin D. Field, Kelly L. Williams, Emily P. McCann, Garth A. Nicholson, Claire E. Shepherd, John R. Hodges, John Landers, Agnes Luty, William S. Brooks, Thomas Fath, Glenda M. Halliday, Mark F. Bennett, Peter K. Panegyres, Peter R. Schofield, Jennifer A. Fifita, Bradley N. Smith, Ian P. Blair, Janice M. Fullerton, Esmeralda Paric, Neil Rajan, Olivier Piguet, John B.J. Kwok, Jane Hecker, Alex D. Shaw, Cathy L. Short, Melanie Bahlo, Carol Dobson-Stone, Shankaracharya, Audrey Ragagnin, Holly Stefen, Hamideh Shahheydari, Francine Carew-Jones, Elizabeth Thompson, Julie D. Atkin, Zac Chatterton, Peter C. Blumbergs, Simon Topp, Christopher Shaw
Publikováno v:
Brain
Frontotemporal dementia and amyotrophic lateral sclerosis are clinically and pathologically overlapping disorders with shared genetic causes. We previously identified a disease locus on chromosome 16p12.1-q12.2 with genome-wide significant linkage in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147cbcedfc0f7e3f90f58f18e7947926
https://doi.org/10.1093/brain/awaa039
https://doi.org/10.1093/brain/awaa039
Publikováno v:
International journal of molecular sciences. 23(5)
Human cells are exposed to numerous exogenous and endogenous insults every day. Unlike other molecules, DNA cannot be replaced by resynthesis, hence damage to DNA can have major consequences for the cell. The DNA damage response contains overlapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5f6b31b7c49d60220d258a3c765f05
https://pubmed.ncbi.nlm.nih.gov/35269632
https://pubmed.ncbi.nlm.nih.gov/35269632