Zobrazeno 1 - 10
of 41
pro vyhledávání: '"D. Andrew James"'
Autor:
Bing Li, Irina V. Ustyugova, Lisa Szymkowicz, Shaolong Zhu, Marin Ming, Karen Y. Y. Fung, Guadalupe Cortés, D. Andrew James, Michael Hrynyk, Nausheen Rahman, Roger H. Brookes, Salvador F. Ausar
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTCurrent influenza vaccines could be augmented by including recombinant neuraminidase (rNA) protein antigen to broaden protective immunity and improve efficacy. Toward this goal, we investigated formulation conditions to optimize rNA physicoch
Externí odkaz:
https://doaj.org/article/b9a83ae88c824934944cdcb2de84a9be
Autor:
Alsawaie, Othman N.1 alsawaie@uaeu.ac.ae
Publikováno v:
British Journal of Educational Technology. Sep2012, Vol. 43 Issue 5, pE143-E143. 10p.
Autor:
Eduardo M. Bruch, Shaolong Zhu, Lisa Szymkowicz, Taylor Blake, Tara Kiss, D. Andrew James, Alexey Rak, Kartik Narayan, Matthew T. Balmer, Roman M. Chicz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, uses a surface expressed trimeric spike glycoprotein for cell entry. This trimer is the primary target for neutralizing antibodies making it
Externí odkaz:
https://doaj.org/article/6498d46d953a4bfcb0fc866354902992
Publikováno v:
Toxins, Vol 13, Iss 11, p 763 (2021)
The antigens for acellular pertussis vaccines are made up of protein components that are purified directly from Bordetella pertussis (B. pertussis) bacterial fermentation. As such, there are additional B. pertussis toxins that must be monitored as re
Externí odkaz:
https://doaj.org/article/cc2c323c6ae141afa35d9bbd31203796
Publikováno v:
Journal of the American Society for Mass Spectrometry
The novel severe respiratory syndrome-like coronavirus (SARS-CoV-2) causes COVID-19 in humans and is responsible for one of the most destructive pandemics of the last century. At the root of SARS-CoV infection is the interaction between the viral spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995fbb6b4ce541cf146a5f982da878a0
https://doi.org/10.1021/jasms.0c00465
https://doi.org/10.1021/jasms.0c00465
Publikováno v:
Biotechnology journalREFERENCES. 17(2)
Background Epitope mapping is an increasingly important aspect of biotherapeutic and vaccine development. Recent advances in therapeutic antibody design and production have enabled candidate mAbs to be identified at a rapidly increasing rate, resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5064a0b7b0b8836ef2c9e183cd00007a
https://pubmed.ncbi.nlm.nih.gov/34747565
https://pubmed.ncbi.nlm.nih.gov/34747565
Autor:
Shaolong Zhu, Peter Liuni, Bruce Carpick, D. Andrew James, Tricia Chen, Luciano Ettorre, Jason Szeto, Derek J. Wilson
Publikováno v:
Biochemistry. 58:646-656
The diphtheria toxoid (DT) antigen is one of the major components in pediatric and booster combination vaccines and is known to raise a protective humoral immune response upon vaccination. However, a structurally resolved analysis of diphtheria toxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36f847edb6d75185efe75b958a1dbbc
https://doi.org/10.1021/acs.biochem.8b01123
https://doi.org/10.1021/acs.biochem.8b01123
This study provides an HDX-MS based analysis of the interaction between the SARS-CoV-2 spike protein and the human Angiotensin Converting Enzyme 2. - The data agree exactly with the X-ray co-crystal structure of this complex, but provide additional i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095d8f02ea07c46aea1843dd0fd08c01
https://doi.org/10.26434/chemrxiv.13385387.v1
https://doi.org/10.26434/chemrxiv.13385387.v1
Autor:
Derek J. Wilson, Stephen Li, Salvador F. Ausar, Thomas Bertrand, Jessica Duprez, Roger H. Brookes, Alexey Rak, D. Andrew James, Artur Pedyczak, Shaolong Zhu, Valerie Steier, Anthony Sheung, Michael X Cohen
Publikováno v:
Communications Biology
'Communications Biology ', vol: 3, pages: 427-1-427-12 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
'Communications Biology ', vol: 3, pages: 427-1-427-12 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
The mutant gdPT R9K/E129G is a genetically detoxified variant of the pertussis toxin (PTx) and represents an attractive candidate for the development of improved pertussis vaccines. The impact of the mutations on the overall protein structure and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c21e5acfc882add69441d72d08636b
http://europepmc.org/articles/PMC7406505
http://europepmc.org/articles/PMC7406505
Publikováno v:
Toxins
Volume 13
Issue 11
Toxins, Vol 13, Iss 763, p 763 (2021)
Volume 13
Issue 11
Toxins, Vol 13, Iss 763, p 763 (2021)
The antigens for acellular pertussis vaccines are made up of protein components that are purified directly from Bordetella pertussis (B. pertussis) bacterial fermentation. As such, there are additional B. pertussis toxins that must be monitored as re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1ed9ed746a6c498cc53ad11d4c7fdf
https://doi.org/10.3390/toxins13110763
https://doi.org/10.3390/toxins13110763