Zobrazeno 1 - 10
of 21
pro vyhledávání: '"D. A. Richie"'
Autor:
Arnold Groehler, Colin R Campbell, Xun Ming, Natalia Y. Tretyakova, Erin D. Michaelson-Richie, Peter W. Villalta
Publikováno v:
DNA Repair (Amst)
1,1,2,2- Cis-diamminedichloroplatinum (II) (cisplatin) is a chemotherapeutic agent widely used in the clinic to treat various cancers. The antitumor activity of cisplatin is generally attributed to its ability to form intrastrand and interstrand DNA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fdb201be94cf929e1eae1717cf6e43
https://europepmc.org/articles/PMC8177102/
https://europepmc.org/articles/PMC8177102/
Autor:
Colin R Campbell, Xun Ming, Erin D. Michaelson-Richie, Natalia Y. Tretyakova, Peter W. Villalta, Arnold Groehler
Platinum-based antitumor drugs such as 1,1,2,2-cis-diamminedichloroplatinum(II) (cisplatin), carboplatin, and oxaliplatin are currently used to treat nearly 50% of all cancer cases, and novel platinum based agents are under development. The antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6d56d88ba19734fe7be5575a6100d2
https://europepmc.org/articles/PMC5567688/
https://europepmc.org/articles/PMC5567688/
Autor:
Melissa Campion, Colin R Campbell, Erin D. Michaelson-Richie, Teshome B. Gherezghiher, Susith Wickramaratne, Sreenivas Kanugula, Anthony E. Pegg, Jamie Kurtz, Xun Ming, Natalia Y. Tretyakova
Publikováno v:
Biochemistry. 52:3171-3181
Although cytotoxic alkylating agents possessing two electrophilic reactive groups are thought to act by cross-linking cellular biomolecules, their exact mechanisms of action have not been established. In cells, these compounds form a mixture of DNA l
Autor:
Erin D. Michaelson-Richie, Natalia Y. Tretyakova, Daniel C. Liebler, Simona G. Codreanu, Xun Ming, Rachel Loeber, Colin R Campbell
Publikováno v:
Journal of Proteome Research. 9:4356-4367
1,2,3,4-diepoxybutane (DEB) is a strongly genotoxic diepoxide hypothesized to be the ultimate carcinogenic metabolite of the common industrial chemical and environmental carcinogen 1,3-butadiene. DEB is a bis-electrophile capable of cross-linking cel
Publikováno v:
VLSI Design, Vol 8, Iss 1-4, Pp 159-163 (1998)
The use of a wavelet basis can lead to efficient methods for performing ab initio electronic structure calculations of inherently localized structures. In this work wavelets are used to construct an adaptive basis which is optimized dynamically throu
Autor:
Colin R Campbell, Simona G. Codreanu, Erin D. Michaelson-Richie, Rachel Loeber, Natalia Y. Tretyakova, Daniel C. Liebler, Xun Ming
Antitumor nitrogen mustards, such as bis(2-chloroethyl)methylamine (mechlorethamine), are useful chemotherapeutic agents with a long history of clinical application. The antitumor effects of nitrogen mustards are attributed to their ability to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7a29ec45dea1b7227a197fe5353fb8
https://europepmc.org/articles/PMC3208907/
https://europepmc.org/articles/PMC3208907/
Autor:
Colin R Campbell, Simona G. Codreanu, Natalia Y. Tretyakova, Rachel Loeber, Daniel C. Liebler, Erin D. Michaelson-Richie
Publikováno v:
Chemical research in toxicology. 22(6)
Nitrogen mustards are antitumor agents used clinically for the treatment of a variety of neoplastic conditions. The biological activity of these compounds is typically attributed to their ability to induce DNA-DNA cross-links. However, nitrogen musta
Autor:
D A Richie, W Y Liang, T.-H. Shen, C T Lin, J E F Frost, R H Williams, David I. Westwood, G A C Jones, M Elliott, A. E. Cornish
Publikováno v:
Superconductor Science and Technology. 4:232-236
Two-dimensional electron gas (2DEGS), formed both at a semiconductor heterojunction and in a delta -doping layer close to a semiconductor surface, have been successfully used to probe the magnetic properties of single-crystal high-Tc superconducting
Autor:
Karl Hess, D. A. Richie
Publikováno v:
Microelectronic Engineering. 47:333-335
Ab initio electronic structure calculations have proven usefull in understanding nanostructure physics. The extension of current methods to large, localized systems remains an active area of research. A key difficulty can be found in the scaling prop
Publikováno v:
Applied Physics Letters. 64:2062-2064
We show the polarization characteristics of gain‐guided vertical‐cavity surface emitting lasers are related to the temperature‐dependent cavity optical resonance and laser gain spectral alignment. Simultaneous nearly degenerate orthogonal eigen