Zobrazeno 1 - 10
of 19
pro vyhledávání: '"D. A. Lomov"'
Publikováno v:
Russian Journal of Organic Chemistry. 58:791-799
Autor:
D. A. Lomov
Publikováno v:
Russian Journal of Organic Chemistry. 55:1093-1098
Readily available 4-methyl-3-nitrobenzenesulfonic acid and 2-methyl-5-nitrophenol were used to develop two alternative approaches to the synthesis of 2-methoxy-4-(methylsulfanyl)benzoic acid in total yields of 17% and 37%, respectively. The synthesis
Publikováno v:
Russian Journal of Organic Chemistry. 54:593-600
Isonicotinic acid ethyl ester reacted with substituted phenacyl bromides to give the corresponding quaternary salts which were reduced with sodium tetrahydridoborate to ethyl 1-(2-aryl-2-hydroxyethyl)-1,2,3,6- tetrahydropyridine-4-carboxylates. The p
Publikováno v:
Russian Journal of Organic Chemistry. 52:1822-1829
Computer simulation at the PM7 level of theory of the structures of imidazo[4,5-c]pyridine derivatives (deaza analogs of purines) and their complexes with Aurora kinase A (AURKA) indicated prospects for their use as potential AURKA inhibitors in the
Autor:
Volodymyr Novikov, M. G. Abramyants, E. Z. Komarovskaya-Porokhnyavets, V. I. Lubenets, D. A. Lomov, Nikolai I. Korotkikh, N. N. Smolyar, N. V. Astashkina
Publikováno v:
Pharmaceutical Chemistry Journal. 50:526-529
A series of 4-(4-dimethylaminophenyl)pyridine derivatives were synthesized and tested for antimicrobial activity. 4-(4-Dimethylaminophenyl)-1-phenacylpyridinium bromide and 4-(4-dimethylaminophenyl)-1-dimethylcarbamoylpyridinium chloride were highly
Publikováno v:
Russian Journal of Organic Chemistry. 52:1610-1615
Oxidative dehydrogenation of 1-aryl(hetaryl)-1,2,3,4-tetrahydro-9Н-β-carboline-3-carboxylic acids derivatives with dimethyl sulfoxide leads to the formation of 1-aryl(hetaryl)-9Н-β-carbolines. Simultaneously with the dehydrogenation decarboxylati
Autor:
D. A. Lomov
Publikováno v:
Russian Journal of Organic Chemistry. 52:51-53
Treatment of 5-amino-1,3-dialkyl-2,3-dihydro-1H-imidazo[4,5-b]pyridin-2-ones with sodium nitrite in aqueous HCl gave 1,3-dialkyl-1H-imidazo[4,5-b]pyridine-2,5(3H,4H)-diones which were nitrated with potassium nitrate in sulfuric acid to 6-nitro deriva
Publikováno v:
Russian Journal of Organic Chemistry. 50:1644-1649
Reaction of allylthiocarbamoyl fragment of N-allylthioureas with excess bromine or iodine leads to the formation of 5-halomethyldihydrothiazole ring as confirms the dehydroiodination of the 5-(5-iodomethyl-4,5-dihydro-1,3-thiazol-2-yl)-4-phenyl-4,5,6
Publikováno v:
Russian Journal of Organic Chemistry. 50:1039-1042
Aromatization of 4-aryl(hetaryl)tetrahydroimidazo[4,5-c]pyridine-6-carboxylic acids and their lithium salts by the action of dimethyl sulfoxide has been revealed for the first time. Heating of these compounds in DMSO for 5–7 h at 90–95°C leads t
Autor:
N. N. Smolyar, D. A. Lomov
Publikováno v:
Russian Journal of Organic Chemistry. 45:421-424
1,3-Dialkyl-5-amino-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones reacted with acetylacetone to give the corresponding 4-(1,3-dialkyl-2-oxo-1,3-dihydro-2H-imidazo[4,5-b]pyridin-5-ylamino)pent-3-en-2-ones which underwent intramolecular cyclization to 1,