Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D. A. Lauffenburger"'
Publikováno v:
The Journal of Immunology. 175:6235-6237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855e0c1f5b98668c39ebc0e7ccaf224d
https://doi.org/10.4049/jimmunol.175.9.6235-b
https://doi.org/10.4049/jimmunol.175.9.6235-b
Publikováno v:
Methods in molecular medicine. 18
Regeneration of functioning tissue essentially involves recapitulating relevant aspects of organogenesis, so that the starting composite of cells, matrix, and molecular factors develops into the desired structure and physiology. A crucial aspect of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b3d19d1ee81e3f9b943b4a48e959cfd
https://pubmed.ncbi.nlm.nih.gov/21370174
https://pubmed.ncbi.nlm.nih.gov/21370174
Autor:
A R, Asthagiri, D A, Lauffenburger
Publikováno v:
Biotechnology progress. 17(2)
Exploiting signaling pathways for the purpose of controlling cell function entails identifying and manipulating the information content of intracellular signals. As in the case of the ubiquitously expressed, eukaryotic mitogen-activated protein kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc377af379769c18f9e893121b83fa36
https://pubmed.ncbi.nlm.nih.gov/11312698
https://pubmed.ncbi.nlm.nih.gov/11312698
Autor:
D V, Schaffer, D A, Lauffenburger
Publikováno v:
Current opinion in molecular therapeutics. 2(2)
Synthetic gene delivery vehicles have made significant progress in the past decade in demonstrating strong potential for targeted delivery to specific cells, low toxicity and immunogenicity and large carrying capacity. However, significant advances m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2986fd870391f254272760ca043b9f30
https://pubmed.ncbi.nlm.nih.gov/11249636
https://pubmed.ncbi.nlm.nih.gov/11249636
Publikováno v:
Biomedical sciences instrumentation. 35
Hollow fiber affinity membranes have potential for use in cell separations because they offer many advantages over currently available techniques. An understanding of the parameters controlling cell attachment and detachment from the surface is vital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e258ca329c03a1335050587f6841a301
https://pubmed.ncbi.nlm.nih.gov/11143370
https://pubmed.ncbi.nlm.nih.gov/11143370
Publikováno v:
Biotechnology and bioengineering. 70(6)
One way to deliver transgenes to cells in a selective manner is to target the delivery vehicles, or vectors, to specific cell-surface receptors as a first step toward ultimate transport of the gene to the nucleus for expression. While selective deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::289d9d1a76996379c69da0505b6e5704
https://pubmed.ncbi.nlm.nih.gov/11064328
https://pubmed.ncbi.nlm.nih.gov/11064328
Publikováno v:
Biotechnology and bioengineering. 70(2)
Combining engineering analyses and mathematical modeling with intervention and detection methodologies at the molecular level will allow manipulation of intracellular signal transduction pathways, and therefore rational control of functional processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81753d51e11dc8d32bf7e5391561feab
https://pubmed.ncbi.nlm.nih.gov/10972934
https://pubmed.ncbi.nlm.nih.gov/10972934
Publikováno v:
Blood. 96(4)
A major limitation to the widespread use of hematopoietic stem cells (HSC) is the relatively crude level of our knowledge of how to maintain these cells in vitro without loss of the long-term multilineage growth and differentiation properties require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::663167e611a9bc43bb43a418cefee38d
https://pubmed.ncbi.nlm.nih.gov/10942360
https://pubmed.ncbi.nlm.nih.gov/10942360
Publikováno v:
Biotechnology and bioengineering. 69(6)
A major limitation of the widespread use of stem cells in a variety of biotechnological applications is the relatively low level of knowledge about how to maintain these cells in vitro without losing the long-term multilineage growth properties requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66e116e937aea6b41cfa5c3d5d511c67
https://pubmed.ncbi.nlm.nih.gov/10918135
https://pubmed.ncbi.nlm.nih.gov/10918135
Publikováno v:
Biotechnology and bioengineering. 67(5)
Ligand-conjugated polymer (polyplex) gene delivery vectors have strong potential as targeted, in vivo gene transfer vehicles; however, they are currently limited by low delivery efficiency. A number of barriers to polyplex-mediated delivery have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9bac53cec04714696d0d2a67ba375837
https://pubmed.ncbi.nlm.nih.gov/10649234
https://pubmed.ncbi.nlm.nih.gov/10649234