Zobrazeno 1 - 10
of 410
pro vyhledávání: '"D. A. HOBBS"'
Autor:
Xinchun Gu, Utkarsh Agrawal, William Midgley, Stuart Bedston, Sneha N. Anand, Rosalind Goudie, Rachel Byford, Mark Joy, Gavin Jamie, Uy Hoang, Jose M. Ordóñez-Mena, Chris Robertson, F. D. Richard Hobbs, Ashley Akbari, Aziz Sheikh, Simon de Lusignan
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Vaccines against COVID-19 and influenza can reduce the adverse outcomes caused by infections during pregnancy, but vaccine uptake among pregnant women has been suboptimal. We examined the COVID-19 and influenza vaccine uptake and disparities
Externí odkaz:
https://doaj.org/article/a47ce09c29e349398e752a12f8c59824
Autor:
James P Sheppard, PhD, Eleanor Temple, MSc, Ariel Wang, PhD, Anne Smith, Stephanie Pollock, DPhil, ProfFMedSci Gary A Ford, DPhil, ProfFMedSci F D Richard Hobbs, DPhil, Nicola Kenealy, BSc, ProfFMedSci Paul Little, BSc, Mark Lown, MRCGP, ProfMD Simon de Lusignan, MRCGP, ProfMD Jonathan Mant, MRCGP, David McCartney, MRCGP, ProfFBPhS Rupert A Payne, MRCGP, Marney Williams, BEd, ProfDPhil Ly-Mee Yu, BEd, ProfPhD Richard J McManus, BEd
Publikováno v:
The Lancet. Healthy Longevity, Vol 5, Iss 8, Pp e563-e573 (2024)
Summary: Background: Deprescribing of antihypertensive medications is recommended for some older patients with low blood pressure and frailty. The OPTiMISE trial showed that this deprescribing can be achieved with no differences in blood pressure con
Externí odkaz:
https://doaj.org/article/99c4b3898fd3455dbed667415247c267
Autor:
F. D. Richard Hobbs, Hugh Montgomery, Francisco Padilla, Jesus Abraham Simón-Campos, Douglas Arbetter, Seth Seegobin, Alexandre Kiazand, Katie Streicher, Nuria Martinez-Alier, Taylor S. Cohen, Mark T. Esser
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 3, Pp 521-533 (2024)
Abstract Introduction In the phase 3 TACKLE study, outpatient treatment with AZD7442 (tixagevimab/cilgavimab) was well tolerated and significantly reduced progression to severe disease or death through day 29 in adults with mild-to-moderate coronavir
Externí odkaz:
https://doaj.org/article/a14226d40c5149da9cdf80a70f127265
Autor:
Joseph F. Standing, Laura Buggiotti, Jose Afonso Guerra-Assuncao, Maximillian Woodall, Samuel Ellis, Akosua A. Agyeman, Charles Miller, Mercy Okechukwu, Emily Kirkpatrick, Amy I. Jacobs, Charlotte A. Williams, Sunando Roy, Luz M. Martin-Bernal, Rachel Williams, Claire M. Smith, Theo Sanderson, Fiona B. Ashford, Beena Emmanuel, Zaheer M. Afzal, Adrian Shields, Alex G. Richter, Jienchi Dorward, Oghenekome Gbinigie, Oliver Van Hecke, Mark Lown, Nick Francis, Bhautesh Jani, Duncan B. Richards, Najib M. Rahman, Ly-Mee Yu, Nicholas P. B. Thomas, Nigel D. Hart, Philip Evans, Monique Andersson, Gail Hayward, Kerenza Hood, Jonathan S. Nguyen-Van-Tam, Paul Little, F. D. Richard Hobbs, Saye Khoo, Christopher Butler, David M. Lowe, Judith Breuer, PANORAMIC Virology Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 symptoms randomised to receive molnupiravir (n = 253) or Us
Externí odkaz:
https://doaj.org/article/01afce3eddb24d8aa3b7e67fa19987db
Autor:
Isobel L. Ward, Chris Robertson, Utkarsh Agrawal, Lynsey Patterson, Declan T. Bradley, Ting Shi, Simon de Lusignan, F. D. Richard Hobbs, Aziz Sheikh, Vahé Nafilyan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-6 (2024)
Abstract The emergence of the COVID-19 vaccination has been critical in changing the course of the COVID-19 pandemic. To ensure protection remains high in vulnerable groups booster vaccinations in the UK have been targeted based on age and clinical v
Externí odkaz:
https://doaj.org/article/3ac0aac1dfad4f18b5bdd8cb5fa53c9e
Autor:
David Herrera, Mariano Sanz, Lior Shapira, Carlos Brotons, Iain Chapple, Thomas Frese, Filippo Graziani, F. D. Richard Hobbs, Olivier Huck, Eva Hummers, Søren Jepsen, Oleg Kravtchenko, Phoebus Madianos, Ana Molina, Mehmet Ungan, Josep Vilaseca, Adam Windak, Shlomo Vinker
Publikováno v:
European Journal of General Practice, Vol 30, Iss 1 (2024)
AbstractBackground Periodontitis is a chronic inflammatory non-communicable disease (NCD) characterised by the destruction of the tooth-supporting apparatus (periodontium), including alveolar bone, the presence of periodontal pockets, and bleeding on
Externí odkaz:
https://doaj.org/article/f9dcf5420f91495fbdff587fd5e88cc7
Autor:
Gregory Y H Lip, Stephen Morris, Richard J McManus, Stephen Sutton, Howard Thom, Mark T Mills, Jonathan Mant, Simon J Griffin, Wern Yew Ding, Sarah Hoare, Jenni Burt, F D Richard Hobbs, Rachel Johnson, Mark Lown, Alison Powell, Natalie Armstrong, Martin Cowie, Trudie Lobban, Ben Freedman, Stephen Kaptoge, Jenny Lund, Duncan Edwards, Kate Williams, Andrew Dymond, Peter Calvert, Rakesh N Modi, Riccardo Proietti, Mike Sweeting
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction There is a lack of evidence that the benefits of screening for atrial fibrillation (AF) outweigh the harms. Following the completion of the Screening for Atrial Fibrillation with ECG to Reduce stroke (SAFER) pilot trial, the aim of the m
Externí odkaz:
https://doaj.org/article/e24145d6495840da97f6fb708ae6928c
Autor:
Gustavo H. Kijak, Bahar Ahani, Douglas Arbetter, Fernando Chuecos, Vancheswaran Gopalakrishnan, Jagadish Beloor, Tyler Brady, Amy Nguyen, Tiffany L. Roe, Nicolette Schuko, Tianhui Zhang, F. D. Richard Hobbs, Francisco Padilla, Elizabeth J. Kelly, Hugh Montgomery, Katie Streicher
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 12, Pp 2691-2707 (2023)
Abstract Introduction AZD7442 (tixagevimab/cilgavimab) comprises neutralising monoclonal antibodies (mAbs) that bind to distinct non-overlapping epitopes on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. Viral evoluti
Externí odkaz:
https://doaj.org/article/81d8ce3337a543ba897387fe3803d1b4
Autor:
F. D. Richard Hobbs, Hugh Montgomery, Francisco Padilla, Jesus Abraham Simón-Campos, Kenneth Kim, Douglas Arbetter, Kelly W. Padilla, Venkatesh Pilla Reddy, Seth Seegobin, Katie Streicher, Alison Templeton, Rolando M. Viani, Eva Johnsson, Gavin C. K. W. Koh, Mark T. Esser
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 9, Pp 2269-2287 (2023)
Abstract Introduction We assessed effects of AZD7442 (tixagevimab/cilgavimab) on deaths from any cause or hospitalizations due to coronavirus disease 2019 (COVID-19) and symptom severity and longer-term safety in the TACKLE adult outpatient treatment
Externí odkaz:
https://doaj.org/article/b097c49509c946169ed5d2c270e2f249
Autor:
Clare R. Goyder, Andrea K. Roalfe, Nicholas R. Jones, Kathy S. Taylor, Charles D. Plumptre, Olivia James, Thomas R. Fanshawe, F D Richard Hobbs, Clare J. Taylor
Publikováno v:
ESC Heart Failure, Vol 10, Iss 3, Pp 1643-1655 (2023)
Abstract Aims Heart failure (HF) is a global health burden and new strategies to achieve timely diagnosis and early intervention are urgently needed. Natriuretic peptide (NP) testing can be used to screen for left ventricular systolic dysfunction (LV
Externí odkaz:
https://doaj.org/article/fa066f17b24c477d845f5987cf54addc