Zobrazeno 1 - 10
of 10
pro vyhledávání: '"D. A. DITTENBER"'
Publikováno v:
Fundamental and Applied Toxicology. 29:119-130
Chlorpyrifos (O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl)-phosphorothioate), an organophosphate insecticide, was evaluated for its potential to produce developmental and reproductive toxicity in rats following oral exposure. Pregnant Fischer 344 rats w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f58dab461be56cda3e759884b8bdd3a
https://doi.org/10.1006/faat.1996.0013
https://doi.org/10.1006/faat.1996.0013
Publikováno v:
Toxicologic Pathology. 20:1-6
Groups of 12 male 42-day-old rats were exposed to 0 or 800 ppm styrene vapors for 14 hr/day, 5 days/ week for 3 weeks. Tone-pip auditory brainstem responses (ABRs) at 4, 8, 16, and 30 kHz were obtained after the last exposure. ABRs were minimally aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb35b1f1a555002eb1193e564395a578
https://doi.org/10.1177/019262339202000101
https://doi.org/10.1177/019262339202000101
Autor:
R.R. Miller, D. A. Dittenber, L. G. Lomax, J. E. Phillips, William J. Breslin, Michael J. Bartels, L. L. Calhoun
Publikováno v:
Fundamental and Applied Toxicology. 17:466-481
Studies were conducted to characterize the hemolytic effects of EGPE in rabbits following oral and dermal exposure, and to evaluate the in vitro hemolytic potential of EGPE and its major metabolite using rabbit red blood cells (RBC). Gavage administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0acb3e6c129ed89eec4477642705fbc1
https://doi.org/10.1016/0272-0590(91)90198-d
https://doi.org/10.1016/0272-0590(91)90198-d
Autor:
W. J. BRESLIN, J. E. PHILLIPS, L. G. LOMAX, M. J. BARTELS, D. A. DITTENBER, L. L. CALHOUN, R. R. MILLER
Publikováno v:
Toxicological Sciences. 17:466-481
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f822786e071f85291c37817c9f8f11b
https://doi.org/10.1093/toxsci/17.3.466
https://doi.org/10.1093/toxsci/17.3.466
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 9:277-299
A systematic evaluation of a flow-through skin penetration chamber, obtained from Oak Ridge National Laboratory, was conducted by measuring in vitro cutaneous penetration with five organic chemicals: urea, caffeine, benzoic acid (BA), salicylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e43cecf068e5bd58501e972328aac633
https://doi.org/10.3109/15569529009036333
https://doi.org/10.3109/15569529009036333
Autor:
R. J. Nolan, Joel L. Mattsson, Kathy A. Brzak, Chuck Timchalk, D. A. Dittenber, A. L. Mendrala
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 66(1)
A PBPK/PD model was developed for the organophosphate insecticide chlorpyrifos (CPF) (O,O-diethyl-O-[3,5,6-trichloro-2-pyridyl]-phosphorothioate), and the major metabolites CPF-oxon and 3,5,6-trichloro-2-pyridinol (TCP) in rats and humans. This model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fde8987155ff11371d128797203b65
https://pubmed.ncbi.nlm.nih.gov/11861971
https://pubmed.ncbi.nlm.nih.gov/11861971
Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 50(1)
This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats. To tease apart these two interre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c735381654a255bd03bb7afe0b4c3218
https://pubmed.ncbi.nlm.nih.gov/10445760
https://pubmed.ncbi.nlm.nih.gov/10445760
Autor:
W J, Breslin, J E, Phillips, L G, Lomax, M J, Bartels, D A, Dittenber, L L, Calhoun, R R, Miller
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 17(3)
Studies were conducted to characterize the hemolytic effects of EGPE in rabbits following oral and dermal exposure, and to evaluate the in vitro hemolytic potential of EGPE and its major metabolite using rabbit red blood cells (RBC). Gavage administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e78523191ad423bd702aef5cb9a96201
https://pubmed.ncbi.nlm.nih.gov/1794651
https://pubmed.ncbi.nlm.nih.gov/1794651
Autor:
R.C. Childs, D. A. Dittenber, J.D. Burek, T.J. Bell, J.E. Beyer, L.W. Rampy, M.J. McKenna, K.D. Nitschke, D.L. Wackerle
Publikováno v:
Fundamental and Applied Toxicology
A long-term study was conducted to determine the possible chronic toxicity and oncogenicity of methylene chloride. Rats and hamsters were exposed by inhalation to 0, 500, 1500, or 3500 ppm of methylene chloride for 6 hr per day, 5 days a week, for 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90da306c2a5681b0bba528d63ad3f558
https://doi.org/10.1016/0272-0590(84)90217-3
https://doi.org/10.1016/0272-0590(84)90217-3
Publikováno v:
Fundamental and Applied Toxicology. 13:616-618
Fischer 344 rats were exposed by the nose-only inhalation route to chlorpyrifos vapors at concentrations of 0, 5.2, 10.3, or 20.6 ppb, 6 hr/day, 5 days/week for 13 weeks. The exposure concentrations were limited by the low vapor pressure of chlorpyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b2c105219b9f78b34be7ce2d6e5f7ad
https://doi.org/10.1016/0272-0590(89)90299-6
https://doi.org/10.1016/0272-0590(89)90299-6