Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D. A. Carbonaro-Hall"'
Autor:
David Warburton, Silvia R. Padilla, Richard Williams, Sue Buckley, D. A. Carbonaro-Hall, Frederick L. Hall, Paul D. Benya
Publikováno v:
Biochemical Journal. 316:303-310
The transforming growth factor beta (TGF-beta) family of growth factors control proliferation, extracellular matrix synthesis and/ or differentiation in a wide variety of cells. However, the molecular mechanisms governing ligand binding, receptor oli
Publikováno v:
Oncology Reports. 2:227-231
Enzymatic activities of cyclin-dependent protein kinases (cdks) are tightly regulated at the level of subunit composition, involving both positive (cyclins) and negative (p21Wafl/Cipl); p16Ink4; p27Kipl) effectors. In the present study, we examined t
Autor:
Paul Greengard, E F da Cruz e Silva, Norbert Berndt, D A Carbonaro-Hall, M Dohadwala, Frederick L. Hall, Angus C. Nairn, R T Williams
Publikováno v:
Scopus-Elsevier
Protein phosphatase 1 and protein phosphatase 2A contain potential phosphorylation sites for cyclin-dependent kinases. In the present study we found that rabbit skeletal muscle protein phosphatase 1, as well as recombinant protein phosphatase 1 alpha
Publikováno v:
Oncology Reports. 1:705-711
Cyclins constitute a growing family of regulatory proteins that complex with, and activate, protein kinases involved in cell cycle control. Dysregulation of cyclin expression and/or cyclin-dependent kinase (cdk) activities may play a pivotal role in
Autor:
Lingtao Wu, Kim Chi Bui, Sue Buckley, Richard Williams, D. A. Carbonaro-Hall, David Warburton, Frederick L. Hall, Frank Wu
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 9:115-125
The mature adult alveolar epithelial cell (AEC) is a highly differentiated phenotype that does not readily divide and exhibits numerous specialized functions. Yet, transformed AEC proliferate aggressively in certain forms of lung cancer. Normal AEC a
Publikováno v:
Journal of Biological Chemistry. 268:8871-8880
Cyclins are key regulatory proteins that, in concert with cyclin-dependent protein kinase subunits (cdks), function to govern critical transitions and/or restriction points during the course of cell cycle progression. Recently, a number of putative m
Autor:
B, Bodey, R T, Williams, D A, Carbonaro-Hall, A, Horvath, V T, Tolo, J V, Luck, C R, Taylor, F L, Hall
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 7(8)
Cyclin proteins in association with cyclin-dependent protein kinase subunits represent a new class of potentially oncogenic serine/threonine protein kinases that function to execute critical cell cycle transitions in all eukaryotic cells. Characteriz
Publikováno v:
Archives of biochemistry and biophysics. 314(1)
The biological activities of cyclin-dependent, proline-directed protein kinases (PDPKs) are highly regulated by a complex series of protein phosphorylation/dephosphorylation reactions involving both catalytic and regulatory subunits. In this paper we
Publikováno v:
Oncogene. 8(5)
Originally identified as a 'mitotic cyclin', cyclin A exhibits properties of growth factor sensitivity, susceptibility to viral subversion and association with a tumor-suppressor protein, properties which are indicative of an S-phase-promoting factor
Publikováno v:
The Journal of biological chemistry. 268(12)
Cyclins are key regulatory proteins that, in concert with cyclin-dependent protein kinase subunits (cdks), function to govern critical transitions and/or restriction points during the course of cell cycle progression. Recently, a number of putative m