Zobrazeno 1 - 10
of 10
pro vyhledávání: '"D. A. Babkov"'
Autor:
D. A. Babkov, A. S. Taran, A. A. Shevchenko, L. V. Naumenko, O. N. Zhukovskaya, A. M. Efremov, E. N. Bezsonova, N. A. Lozinskaya, A. A. Spasov
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 1, Pp 116-128 (2024)
Background. Melatonin is an endogenous regulator of intraocular pressure (IOP), but its effectiveness as a drug for glaucoma treatment is limited.The aim of the study. To develop and to validate a virtual screening method to identify bioisosteric ana
Externí odkaz:
https://doaj.org/article/f1d1f8168ad943f3b9de3398ea2a659c
Autor:
D. A. Babkov
Publikováno v:
Безопасность и риск фармакотерапии, Vol 11, Iss 3, Pp 322-335 (2023)
Scientific relevance. Endocrine disruptors affect the functioning of endocrine organs, which leads to adverse drug reactions. Endocrine toxicity requires special attention in preclinical studies of candidate medicinal products.Aim. The study aimed to
Externí odkaz:
https://doaj.org/article/699e6bb90e064dd8a1daaede7f87ea76
Autor:
A. A Spasov, L. V. Naumenko, D. S Yakovlev, A. S Taran, E. V Sokolova, V. G Klochkov, A. V Borisov, E. N Bezsonova, A. M Efremov, N. A Lozinskay, D. A Babkov
Publikováno v:
Journal of Volgograd State Medical University. 19:94-103
Resume. Aim. Glaucoma is a whole group of diseases caused by increased intraocular pressure (IOP), leading to atrophy of the optic nerve and irreversible blindness. Melatonin has a wide range of biological activity, including antioxidant and antiglau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::defa3aee693792c47213f27eacc88788
https://doi.org/10.19163/1994-9480-2022-19-4-94-103
https://doi.org/10.19163/1994-9480-2022-19-4-94-103
Autor:
E. R. Milaeva, D. B. Shpakovsky, E. V. Radchenko, V. A. Palyulin, D. A. Babkov, A. V. Borisov, M. A. Dodokhova, A. V. Safronenko, I. M. Kotieva, A. A. Spasov
Publikováno v:
Russian Chemical Bulletin. 71:2605-2611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029e1ede1b25e4566db5efdba7eb2091
https://doi.org/10.1007/s11172-022-3689-6
https://doi.org/10.1007/s11172-022-3689-6
Autor:
A. A. Spasov, O. N. Zhukovskaya, N. A. Gurova, L. V. Naumenko, N. V. Eliseeva, A. F. Kucheryavenko, V. A. Kosolapov, D. S. Yakovlev, V. Y. Muravyeva, V. A. Babkova, D. A. Babkov, J. V. Lifanova, A. S. Morkovnik
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:281-291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156acb7d34f4b641a7dd7ee9ae58957c
https://doi.org/10.1134/s1068162022020236
https://doi.org/10.1134/s1068162022020236
Publikováno v:
Natural product research.
A series of 24-ethylcholest-4-ene-3,6-dione 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f49322f4a0313ebe34ea8e0c651695a4
https://pubmed.ncbi.nlm.nih.gov/35895012
https://pubmed.ncbi.nlm.nih.gov/35895012
A series of 24-ethylcholest-4-ene-3,6-dione 2E-arylidene-derivatives has been synthesized by a Claisen-Schmidt reaction from a natural phytosterol β-sitosterol with yields of 80–85%. The structure of the obtained compounds was confirmed by NMR spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e4721a1a031eee8e9936fdc4bc5a94
Autor:
A. A Spasov, D. A Babkov, A. B Smirnov, Yu. I Velikorodnaya, L. V Naumehko, A. S Taran, Yulia A. Govorova
Publikováno v:
Medical Journal of the Russian Federation. 25:303-308
Nonenzymatic glycosylation of lens proteins in diabetes mellitus is one of the pathogenetic mechanisms of cataract formation. According to the results of this study, aminoguanidine, which has anti-glycation activity, inhibits cataractogenesis in expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6afdaf5741d0becc8ab772778e548d9
https://doi.org/10.18821/0869-2106-2019-25-5-6-303-308
https://doi.org/10.18821/0869-2106-2019-25-5-6-303-308
Autor:
P. M. Vasilyev, O. A. Luzina, D. A. Babkov, Nariman F. Salakhutdinov, A. A. Spasov, D. T. Appazova
Publikováno v:
Journal of Structural Chemistry. 60:1827-1832
The method of similarity to standards is used to calculate the spectrum of targeted hypoglycemic activities of a series of natural compounds of terpenoid and polyphenol classes. Some compounds are shown to be promising multitargeted hypoglycemic agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f3b044272b5e58e4460e9bf14d11b7d
https://doi.org/10.1134/s0022476619110179
https://doi.org/10.1134/s0022476619110179
Autor:
E S, Matyugina, M S, Novikov, D A, Babkov, V T, Valuev-Elliston, C, Vanpouille, S, Zicari, A, Corona, E, Tramontano, L B, Margolis, A L, Khandazhinskaya, S N, Kochetkov
Publikováno v:
Acta Naturae
Several 5-aminouracil derivatives that have previously been shown to inhibit Mycobacterium tuberculosis growth at concentrations of 5–40 μg/mL are demonstrated to act also as noncompetitive non-nucleoside inhibitors of HIV-1 reverse transcriptase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45449576559ca76738339b771ff260cc
https://pubmed.ncbi.nlm.nih.gov/26483967
https://pubmed.ncbi.nlm.nih.gov/26483967