Zobrazeno 1 - 10
of 445
pro vyhledávání: '"D. Offen"'
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background Partial or an entire deletion of SHANK3 are considered as major drivers in the Phelan–McDermid syndrome, in which 75% of patients are diagnosed with autism spectrum disorder (ASD). During the recent years, there was an increasin
Externí odkaz:
https://doaj.org/article/09578129a97d4d7f9ce85dee36328243
Autor:
Moshe Gavish, John P M Finberg, Abraham Weizman, D. Offen, Yelena Loboda, Hadar Segal-Gavish, Yael Barhum, Martin Gabay, Avishai Gavish, Meygal Kahana, Nahum Allon
Publikováno v:
Molecular Psychiatry. 26:2626-2632
Delivery of drugs into the brain is poor due to the blood brain barrier (BBB). This study describes the development of a novel liposome-based brain-targeting drug delivery system. The liposomes incorporate a diacylglycerol moiety coupled through a li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a087c1c9e27d444b641270c8809414c
https://doi.org/10.1038/s41380-020-0742-4
https://doi.org/10.1038/s41380-020-0742-4
Akademický článek
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Additional file 2: Figure S1. rtPCR for inflammatory markers shows no significant difference between the groups. A. TNFα B. IBA1 C. IL1. One-way ANOVA followed with Tukey’s post hoc was done for the rtPCR analysis. Data is presented as means Error
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cce215a5487b20329df2c9f5153a06
Autor:
Rea Globus, Amir Bieber, Shira Dar, M. Vescan, Hadar Segal-Gavish, Jack W. Lipton, Shorena Janelidze, Israel Aharony, Abraham Weizman, D. Naor, Lena Brundin, D. Offen, Ran Barzilay, Filip Ventorp
Publikováno v:
Journal of Molecular Neuroscience. 60:548-558
CD44 is a cell surface adhesion molecule and its principal ligand is hyaluronic acid (HA), a key component of the brain's extracellular matrix. CD44 levels are decreased in the cerebrospinal fluid (CSF) of depressed individuals, and the CD44 gene has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c92895a17c7271898f4dc68ab7e6e81
https://doi.org/10.1007/s12031-016-0835-3
https://doi.org/10.1007/s12031-016-0835-3
Autor:
Oshra Betzer, D. Offen, Nisim Perets, Shulamit Levenberg, Anton Sheinin, Rachela Popovtzer, Shahar Ben-Shaul, I. Michaelevski, Shaowei Guo
Publikováno v:
Cytotherapy. 21:e7-e8
Background & Aim Complete spinal cord injury (SCI) is a debilitating disease which usually leads to permanent functional impairments, with various complications and limited spontaneous recovery or effective treatment. Here, we report that in rats wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5d0f842872fbba8761b17966c5f415
https://doi.org/10.1016/j.jcyt.2019.04.024
https://doi.org/10.1016/j.jcyt.2019.04.024
Publikováno v:
Cytotherapy. 21:e6-e7
Background & Aim CRISPR is a promising novel technology for treating genetic conditions. Therefore, it is essential to further develop and promote treatment's safety and specificity. While the guide RNA offers position-specific DNA targeting, it may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4d38483ae62687b4345ed2b3153ad45
https://doi.org/10.1016/j.jcyt.2019.04.021
https://doi.org/10.1016/j.jcyt.2019.04.021
Publikováno v:
Cytotherapy. 21:e6
Background & Aim Myeloperoxidase (MPO) is a potent enzyme expressed mostly by neutrophils, that catalyzes the formation of reactive oxygen species (ROS), mainly hypochlorous acid. MPO is a primary mediator of neutrophils oxidative stress response and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fefb5f6a9ab9484d3a270408d5708635
https://doi.org/10.1016/j.jcyt.2019.04.018
https://doi.org/10.1016/j.jcyt.2019.04.018
Publikováno v:
Cytotherapy. 21:e6
Background & Aim One of the greatest challenges in both neurology and psychiatry is targeted drug delivery. Most of the molecules do not cross the blood-brain barrier, and those who cross it do not target the damaged area in the brain and causes majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fb6c9c417a60d3c53678a223a51470
https://doi.org/10.1016/j.jcyt.2019.04.020
https://doi.org/10.1016/j.jcyt.2019.04.020
Publikováno v:
Cytotherapy. 21:e8
Background & Aim Mesenchymal stem cells (MSC) have shown to have regenerative and immunomodulatory abilities when they are transplanted into a tissue. we have previously demonstrated that stereotactical injection of MSC into the brains of BTBR mice -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9442eb9b40233d0089985245ff075c94
https://doi.org/10.1016/j.jcyt.2019.04.025
https://doi.org/10.1016/j.jcyt.2019.04.025