Zobrazeno 1 - 10
of 2 412
pro vyhledávání: '"D. McKay"'
Understanding the biological processes of kidney carcinogenesis: an integrative multi-omics approach
Autor:
Ricardo Cortez Cardoso Penha, Alexandra Sexton Oates, Sergey Senkin, Hanla A Park, Joshua Atkins, Ivana Holcatova, Anna Hornakova, Slavisa Savic, Simona Ognjanovic, Beata Świątkowska, Jolanta Lissowska, David Zaridze, Anush Mukeria, Vladimir Janout, Amelie Chabrier, Vincent Cahais, Cyrille Cuenin, Ghislaine Scelo, Matthieu Foll, Zdenko Herceg, Paul Brennan, Karl Smith-Byrne, Nicolas Alcala, James D Mckay
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 12, Pp 1282-1302 (2024)
Abstract Biological mechanisms related to cancer development can leave distinct molecular fingerprints in tumours. By leveraging multi-omics and epidemiological information, we can unveil relationships between carcinogenesis processes that would othe
Externí odkaz:
https://doaj.org/article/a826898908c949ca9476ef69f644d069
Autor:
Bryan R. Gorman, Sun-Gou Ji, Michael Francis, Anoop K. Sendamarai, Yunling Shi, Poornima Devineni, Uma Saxena, Elizabeth Partan, Andrea K. DeVito, Jinyoung Byun, Younghun Han, Xiangjun Xiao, Don D. Sin, Wim Timens, Jennifer Moser, Sumitra Muralidhar, Rachel Ramoni, Rayjean J. Hung, James D. McKay, Yohan Bossé, Ryan Sun, Christopher I. Amos, VA Million Veteran Program, Saiju Pyarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous lung cancer GWAS have identified numerous loci, but separating the genetic risks of lung cancer and smoking behavioral susceptibility remain
Externí odkaz:
https://doaj.org/article/dac86f32ac504f5bbdb7376d6931934e
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Characterising how the totality of primate diversity is distributed across the order, and how it evolved, is challenging because diversity in individual traits often show opposing phylogenetic patterns. A species’ combination of traits can
Externí odkaz:
https://doaj.org/article/df2404105f0045359be5d44bf1a63f3a
Autor:
Xinan Wang, Ziwei Zhang, Yi Ding, Tony Chen, Lorelei Mucci, Demetrios Albanes, Maria Teresa Landi, Neil E. Caporaso, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, Gadi Rennert, Susanne Arnold, Paul Brennan, James D. McKay, John K. Field, Sanjay S. Shete, Loic Le Marchand, Geoffrey Liu, Angeline S. Andrew, Lambertus A. Kiemeney, Shan Zienolddiny-Narui, Annelie Behndig, Mikael Johansson, Angie Cox, Philip Lazarus, Matthew B. Schabath, Melinda C. Aldrich, Rayjean J. Hung, Christopher I. Amos, Xihong Lin, David C. Christiani
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Although polygenic risk score (PRS) has emerged as a promising tool for predicting cancer risk from genome-wide association studies (GWAS), the individual-level accuracy of lung cancer PRS and the extent to which its impact on sub
Externí odkaz:
https://doaj.org/article/f2a83eace6cb48e6be31892d21e98222
Autor:
Christopher K. Tuggle, Jennifer L. Clarke, Brenda M. Murdoch, Eric Lyons, Nicole M. Scott, Bedrich Beneš, Jacqueline D. Campbell, Henri Chung, Courtney L. Daigle, Sruti Das Choudhury, Jack C. M. Dekkers, Joao R. R. Dórea, David S. Ertl, Max Feldman, Breno O. Fragomeni, Janet E. Fulton, Carmela R. Guadagno, Darren E. Hagen, Andrew S. Hess, Luke M. Kramer, Carolyn J. Lawrence-Dill, Alexander E. Lipka, Thomas Lübberstedt, Fiona M. McCarthy, Stephanie D. McKay, Seth C. Murray, Penny K. Riggs, Troy N. Rowan, Moira J. Sheehan, Juan P. Steibel, Addie M. Thompson, Kara J. Thornton, Curtis P. Van Tassell, Patrick S. Schnable
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Dramatic improvements in measuring genetic variation across agriculturally relevant populations (genomics) must be matched by improvements in identifying and measuring relevant trait variation in such populations across many environments (ph
Externí odkaz:
https://doaj.org/article/16775bc608354ceabfd4ba8fddc9415e
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/9f7a56a3eca04d1380116f98e07acb5a
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 10, Iss 1 (2024)
Objective This study describes the incidence, severity and burden of match injuries in schoolboy rugby union in England, across three age groups: under-13 (U13), under-15 (U15) and under-18 (U18).Methods Data regarding 574 24-hour time-loss match inj
Externí odkaz:
https://doaj.org/article/8136c2327454406bb3ffdcb62a4457a1
Autor:
Keith A Stokes, Ben Langley, Nicholas Peirce, Amy Williams, Sean Williams, Thamindu Wedatilake, Carly D McKay, Luke Goggins, Steve Griffin, Anna Warren
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 10, Iss 1 (2024)
Objectives To describe the injury profile of a novel format cricket competition (‘The Hundred’) and compare injury incidence and prevalence between the men’s and women’s competitions.Methods Medical staff prospectively collected injury data f
Externí odkaz:
https://doaj.org/article/a02677f57204484fa1e4f69f35b00746
Autor:
Kathryn Prame Kumar, Jenny L. Wilson, Huynh Nguyen, Liam D. McKay, Shu Wen Wen, Tara Sepehrizadeh, Michael de Veer, Pradeep Rajasekhar, Simona E. Carbone, Michael J. Hickey, Daniel P. Poole, Connie H. Y. Wong
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Gut dysmotility is common after ischemic stroke, but the mechanism underlying this response is unknown. Under homeostasis, gut motility is regulated by the neurons of the enteric nervous system that control contractile/relaxation activity
Externí odkaz:
https://doaj.org/article/303acb2ee544421b893a1f5027677127
In 1920, David O. McKay embarked on a journey that forever changed the Church of Jesus Christ of Latter-day Saints. His visits to the Latter-day Saint missions, schools, and branches in the Pacific solidified the Church leadership's commitment to glo
