Výsledky vyhledávání - "D. G. C. OWENS"

Brain structure, genetic liability, and psychotic symptoms in subjects at high risk of developing schizophrenia

Autor: Jonathan J.K. Best, Julia N Kestelman, Lorna Donnelly, Eve C. Johnstone, Patrick Miller, Suheib S. Abukmeil, Heather C. Whalley, D. G. C. Owens, Stephen M. Lawrie

Publikováno v: Biological Psychiatry. 49:811-823

Background: Structural magnetic resonance imaging (MRI) of the brain in patients with schizophrenia has consistently demonstrated several abnormalities. These are thought to be neurodevelopmental in origin, as they have also been described in first e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713841d4aa9615ebb7c01157f63b85f2
https://doi.org/10.1016/s0006-3223(00)01117-3

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Edinburgh high risk study — findings after four years: demographic, attainment and psychopathological issues

Autor: Stephen M. Lawrie, A. Hodges, Majella Byrne, Eve C. Johnstone, D. G. C. Owens, R. Clafferty, Suheib S. Abukmeil, Elizabeth Grant

Publikováno v: Schizophrenia Research. 46:1-15

This study reports findings of the Edinburgh High Risk Study four years after it began. This study is designed to explore the pathogenesis of schizophrenia by examining a large sample of young adults aged 16-25 years who are at enhanced risk of devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a657f2c07f50a57582c884103de6ab2e
https://doi.org/10.1016/s0920-9964(99)00225-x

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Neuropsychological assessment of young people at high genetic risk for developing schizophrenia compared with controls: preliminary findings of the Edinburgh High Risk Study (EHRS)

Autor: Elizabeth Grant, Eve C. Johnstone, Majella Byrne, A. Hodges, D. G. C. Owens

Publikováno v: Psychological Medicine. 29:1161-1173

Background. Finding risk indicators for schizophrenia among groups of individuals at high genetic risk for the disorder, has been the driving force of the high risk paradigm. The current study describes the preliminary results of a neuropsychological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a0422b38c42efbf81006450ff25a85
https://doi.org/10.1017/s0033291799001002

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Determinants of the Extremes of Outcome in Schizophrenia

Autor: D. G. C. Owens, E. C. Johnstone, F. H. Lang, C. D. Frith

Publikováno v: British Journal of Psychiatry. 167:604-609

BackgroundAlthough poor prognosis has been considered a defining characteristic of schizophrenia, long-term studies show marked heterogeneity of outcome.MethodAssessments of positive and negative symptoms, premorbid and current IQ, and months of in-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6c56fee14aed770d7272eafb59846e
https://doi.org/10.1192/bjp.167.5.604

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The Northwick Park ‘Functional’ Psychosis Study: diagnosis and outcome

Autor: C. D. Frith, D. G. C. Owens, Eve C. Johnstone, T. J. Crow, A. Charlette, E. J. Baldwin, D.J. Done

Publikováno v: Psychological Medicine. 22:331-346

SYNOPSISThree hundred and twenty-six consecutively admitted patients with functional psychotic illnesses to which no diagnostic classification had been applied were followed up after 2·5 years. They were examined in social, clinical and psychologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b582fc7b9c990cb19522d8b76e34af4e
https://doi.org/10.1017/s0033291700030270

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III. Clinical Findings. Abnormalities of the Mental State and Movement Disorder and their Correlates

Autor: C. D. Frith, D. G. C. Owens, Eve C. Johnstone, J. Leary

Publikováno v: British Journal of Psychiatry. 159:21-25

Persisting positive symptoms largely unresponsive to treatment (Tuma & May, 1979; Macmillan et al, 1986; May et al, 1989) occur in about 7% of patients with schizophrenia but lesser degrees of treatment resistance are common (Hogarty, 1988; Johnstone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dda7f49cf5213b864d4005c132ae2df
https://doi.org/10.1192/s0007125000296311

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II. Social Outcome

Autor: D. G. C. Owens, J. Leary, Eve C. Johnstone

Publikováno v: British Journal of Psychiatry. 159:13-20

The social disadvantages for schizophrenic patients in terms of unemployment, impaired relationships, social isolation and downward social drift have been well described (Cooper, 1961; Goldberg & Morrison, 1963; Cheadle et al, 1978; Taylor, 1987). Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d0c7b7467b13053c3ee44d7fdc31b4b
https://doi.org/10.1192/s000712500029630x

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I. Background, Method, and General Description of the Sample

Autor: D. G. C. Owens, S. Wilkins, C. D. Frith, J. Leary, H. I. Hershon, Eve C. Johnstone

Publikováno v: British Journal of Psychiatry. 159:7-12

The aims of this study were to identify and trace all schizophrenic patients discharged from in-patient and day-patient psychiatric services in Harrow between 1 January 1975 and 1 January 1985, to examine the patients in terms of their mental state,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b650c3de413ccb70a60aba89fd9d6f92
https://doi.org/10.1192/s0007125000296293

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