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of 382
pro vyhledávání: '"D-BOX"'
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1146-1157 (2024)
2’-O-ribose methylation (2’-O-Me) is one of the most common RNA modifications detected in ribosomal RNAs (rRNA) from bacteria to eukaryotic cells. 2’-O-Me favours a specific RNA conformation and protects RNA from hydrolysis. Moreover, rRNA 2’
Externí odkaz:
https://doaj.org/article/a529af49fa664df4a971adcf02fa4c15
Publikováno v:
Parasitology, Vol 151, Pp 539-545 (2024)
Small nucleolar RNAs (snoRNAs) are short non-coding RNAs that are abundant in the nucleoli of eukaryotic cells and play a crucial role in various aspects of ribosomal RNA (rRNA) maturation, including modifications such as 2′-O-methylation or pseudo
Externí odkaz:
https://doaj.org/article/b0681da1410d4df0a116f96668b27623
Autor:
Noah Peter Jagielski, Amit Kumar Rai, K. Shanmugha Rajan, Vatsal Mangal, Venkata Naga Srikanth Garikipati
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102087- (2024)
As cardiovascular diseases continue to be the leading cause of death worldwide, groundbreaking research is being conducted to mitigate their effects. This review looks into the potential of small nucleolar RNAs (snoRNAs) and the opportunity to use th
Externí odkaz:
https://doaj.org/article/b65141fcf9224d1a9eb2a51ec2f2b73b
Publikováno v:
Biomolecules & Biomedicine (2024)
Vascular calcification (VC) is a critical complication in chronic kidney disease (CKD), where transcription factors (TFs) and microRNAs (miRs) could potentially play a pivotal role in its pathogenesis and progression. To explore the potential molecul
Externí odkaz:
https://doaj.org/article/1dcf3a1d01de430687fc5fd65f9e8b1a
Publikováno v:
BioTechniques, Vol 74, Iss 5, Pp 225-235 (2023)
Ribose 2′O-methylation (Nm, ribomethylation) is the most abundant RNA modification present in rRNA. It has been shown that alterations in ribosomal 2′O-methylation at individual Nm sites likely reflect regulated cellular processes. Although sever
Externí odkaz:
https://doaj.org/article/7dc12336bc0142a7831ffccc9c708bb7
Autor:
Eva van Ingen, Pleun A.M. Engbers, Tamar Woudenberg, M. Leontien van der Bent, Hailiang Mei, Johann Wojta, Paul H.A. Quax, A. Yaël Nossent
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 162-172 (2022)
C/D box small nucleolar RNAs (snoRNAs) of the DLK1-DIO3 locus are associated with vascular remodeling and cardiovascular disease. None of these snoRNAs has any known targets yet except for one, AF357425/SNORD113-6. We previously showed that this snoR
Externí odkaz:
https://doaj.org/article/611b5447849f4d83868b5251b99cc594
Akademický článek
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Autor:
Yancheng Liu, Yuko Takagi, Milyadi Sugijanto, Kieu Duong My Nguyen, Akira Hirata, Hiroyuki Hori, C. Kiong Ho
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
RNA ligases play important roles in repairing and circularizing RNAs post-transcriptionally. In this study, we generated an allelic knockout of ATP-dependent RNA ligase (Rnl) in the hyperthermophilic archaeon Thermococcus kodakarensis to identify its
Externí odkaz:
https://doaj.org/article/0f639df7041c436dbc3be403f67a1522
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Post-transcriptional modifications fulfill many important roles during ribosomal RNA maturation in all three domains of life. Ribose 2'-O-methylations constitute the most abundant chemical rRNA modification and are, for example, involved in RNA foldi
Externí odkaz:
https://doaj.org/article/e6b9f8b4a159400f810e3f0e870967ef
Akademický článek
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