Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women

Autor: Delores J. Grant, Ani Manichaikul, Anthony J. Alberg, Elisa V. Bandera, Jill Barnholtz‐Sloan, Melissa Bondy, Michele L. Cote, Ellen Funkhouser, Patricia G. Moorman, Lauren C. Peres, Edward S. Peters, Ann G. Schwartz, Paul D. Terry, Xin‐Qun Wang, Temitope O. Keku, Cathrine Hoyo, Andrew Berchuck, Dale P. Sandler, Jack A. Taylor, Katie M. O’Brien, Digna R. Velez Edwards, Todd L. Edwards, Alicia Beeghly‐Fadiel, Nicolas Wentzensen, Celeste Leigh Pearce, Anna H. Wu, Alice S. Whittemore, Valerie McGuire, Weiva Sieh, Joseph H. Rothstein, Francesmary Modugno, Roberta Ness, Kirsten Moysich, Mary Anne Rossing, Jennifer A. Doherty, Thomas A. Sellers, Jennifer B. Permuth‐Way, Alvaro N. Monteiro, Douglas A. Levine, Veronica Wendy Setiawan, Christopher A. Haiman, Loic LeMarchand, Lynne R. Wilkens, Beth Y. Karlan, Usha Menon, Susan Ramus, Simon Gayther, Aleksandra Gentry‐Maharaj, Kathryn L. Terry, Daniel W. Cramer, Ellen L. Goode, Melissa C. Larson, Scott H. Kaufmann, Rikki Cannioto, Kunle Odunsi, John L. Etter, Ruea‐Yea Huang, Marcus Q. Bernardini, Alicia A. Tone, Taymaa May, Marc T. Goodman, Pamela J. Thompson, Michael E. Carney, Shelley S. Tworoger, Elizabeth M. Poole, Diether Lambrechts, Ignace Vergote, Adriaan Vanderstichele, Els Van Nieuwenhuysen, Hoda Anton‐Culver, Argyrios Ziogas, James D. Brenton, Line Bjorge, Helga B. Salvensen, Lambertus A. Kiemeney, Leon F. A. G. Massuger, Tanja Pejovic, Amanda Bruegl, Melissa Moffitt, Linda Cook, Nhu D. Le, Angela Brooks‐Wilson, Linda E. Kelemen, Paul D.P. Pharoah, Honglin Song, Ian Campbell, Diana Eccles, Anna DeFazio, Catherine J. Kennedy, Joellen M. Schildkraut

Publikováno v: Cancer Medicine, Vol 8, Iss 5, Pp 2503-2513 (2019)

Abstract An association between genetic variants in the vitamin D receptor (VDR) gene and epithelial ovarian cancer (EOC) was previously reported in women of African ancestry (AA). We sought to examine associations between genetic variants in VDR and

Externí odkaz: https://doaj.org/article/e1138d0ca72749ca892bbfadf3342940

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Interplay between SARS‐CoV‐2‐derived miRNAs, immune system, vitamin D pathway and respiratory system

Autor: Pegah Mousavi, Maryam Yari, Mehdi Hassani Azad, Elham Karimi, Hanieh Azari, Ahmad Tahmasebi

Publikováno v: Journal of Cellular and Molecular Medicine

The new coronavirus pandemic started in China in 2019. The intensity of the disease can range from mild to severe, leading to death in many cases. Despite extensive research in this area, the exact molecular nature of virus is not fully recognized; h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9675a4d94d4724b5cc19d80b864b04b
https://doi.org/10.1111/jcmm.16694

Genetic Polymorphisms in the Vitamin D Pathway and Non-small Cell Lung Cancer Survival

Autor: Xiao-Jie Chen, Biyun Qian, Jinyu Kong, Shegan Gao, Herbert Yu, Jingxin Li, Fangxiu Xu, Jian Wang

Publikováno v: Pathology Oncology Research

Various genetic polymorphisms have been linked to lung cancer susceptibility and survival outcomes. Vitamin D (VD) regulates cell proliferation and differentiation, inhibits tumor growth and induces apoptosis. Observations from several previous studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d423ae599df64c367ba5713af801bce8
https://doi.org/10.1007/s12253-019-00702-4

Association of vitamin D pathway genes polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population

Autor: Si-Jiu Shi, Li Wei, Hong-Miao Li, Shuang-Shuang Chen, Gen-You Zhang, Tian-Ping Zhang

Publikováno v: Genes & Nutrition

Objective This study aimed to evaluate the association of single nucleotide polymorphisms (SNPs) of vitamin D metabolic pathway genes with susceptibility to pulmonary tuberculosis (PTB). Methods Nine hundred seventy-nine patients (490 PTB cases and 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66217fd4bd9445379231846e012aa136
https://doi.org/10.1186/s12263-021-00687-3