Zobrazeno 1 - 10
of 637
pro vyhledávání: '"D Wetzel"'
Autor:
Michael D. Wetzel, Joseph C. Wenke
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Ischemia–reperfusion injury is caused by a period of ischemia followed by massive blood flow into a tissue that had experienced restricted blood flow. The severity of the injury is dependent on the time the tissue was restricted from blood
Externí odkaz:
https://doaj.org/article/7120221edbe846ba88e90b02d2bf0386
Autor:
Michael D. Wetzel, Kristen Stanley, Soumya Maity, Muniswamy Madesh, Jean C. Bopassa, Alaa S. Awad
Publikováno v:
Physiological Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Recently we showed that homoarginine supplementation confers kidney protection in diabetic mouse models. In this study we tested whether the protective effect of homoarginine is nitric oxide synthase‐3 (NOS3)‐independent in diabetic neph
Externí odkaz:
https://doaj.org/article/f707223766d44a32a1abf424534cbdad
Publikováno v:
Polymer Engineering & Science. 63:1528-1538
Autor:
Michael D. Wetzel, Kristen Stanley, Wei Wei Wang, Soumya Maity, Muniswamy Madesh, W. Brian Reeves, Alaa S. Awad
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Fibrosis is the final common pathway in the pathophysiology of most forms of chronic kidney disease (CKD). As treatment of renal fibrosis still remains largely supportive, a refined understanding of the cellular and molecular mechanisms of kidney fib
Externí odkaz:
https://doaj.org/article/483b48be22c64c11a53ed382f43916ae
Publikováno v:
Polymer Engineering & Science. 62:3377-3389
Publikováno v:
Physiological Reports, Vol 7, Iss 18, Pp n/a-n/a (2019)
Abstract l‐homoarginine is an endogenous, non‐proteinogenic amino acid that has emerged as a new player in health and disease. Specifically, low l‐homoarginine levels are associated with cardiovascular diseases, stroke, and reduced kidney funct
Externí odkaz:
https://doaj.org/article/70c13744244046ab95a47ffc6ed3d68d
Supplemental Figure 1. A. Western blot of purified preparations of human latent and active HPSE recombinant proteins showing distinct molecular weights, β-actin was probed as a loading control. M.W. standards were run in parallel with samples (left
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ecfcecd536495e05e1abc77d74036a
https://doi.org/10.1158/1541-7786.22517535.v1
https://doi.org/10.1158/1541-7786.22517535.v1
Autor:
Mark D. Wetzel, Gregory A. Campbell
Publikováno v:
Polymer Engineering & Science. 62:2592-2609
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 1, Pp 101-113 (2015)
Heparanase (HPSE) is the dominant mammalian endoglycosidase and important tumorigenic, angiogenic, and pro-metastatic molecule. Highest levels of HPSE activity have been consistently detected in cells possessing highest propensities to colonize the b
Externí odkaz:
https://doaj.org/article/a3be0fc4425f482288fbd2b407753fa4
Publikováno v:
Annals of Biomedical Engineering. 49:2886-2900
Impacts to the back of the head due to rearward falls, also referred to as “backfall” events, represent a common source of TBI for athletes and soldiers. A new experimental apparatus is described for replicating the linear and rotational kinemati