Zobrazeno 1 - 10
of 28
pro vyhledávání: '"D W Riches"'
Publikováno v:
The Journal of Immunology. 159:4491-4497
TNF-alpha regulates the expression of many proinflammatory and profibrogenic gene products in macrophages, and hence plays a vital role in controlling the inflammatory response. We have shown previously that exposure of macrophages to TNF-alpha stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd49a925bdf184d3de3b41aa93c0cf1d
https://doi.org/10.4049/jimmunol.159.9.4491
https://doi.org/10.4049/jimmunol.159.9.4491
Publikováno v:
The Journal of Immunology. 158:3433-3438
Fc gamma R cross-linking on murine macrophages resulted in the activation of mitogen-activated protein kinase (MAPK) family members p42MAPK, p38, and c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase (SAPK). The temporal pattern of acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::027b13dbd9ad85b1a98c85c8bbcf5e76
https://doi.org/10.4049/jimmunol.158.7.3433
https://doi.org/10.4049/jimmunol.158.7.3433
Publikováno v:
The Journal of Immunology. 155:5819-5825
The specific recognition of phosphatidylserine (PS) by macrophages is believed to be one means by which effete and apoptotic cells expressing PS on their outer membrane leaflet are targeted for phagocytosis. The aim of this study was to better unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b1d8921d4c020dffec729b0cb3585e
https://doi.org/10.4049/jimmunol.155.12.5819
https://doi.org/10.4049/jimmunol.155.12.5819
Publikováno v:
The Journal of Immunology. 155:2123-2133
Increased synthesis of insulin-like growth factor I (IGF-I), a fibroblast growth factor, is induced in murine macrophages by TNF-alpha. TNF-alpha also induces macrophages to express cytocidal activity, but only during costimulation with IFNs. Since p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8e81441762195a408bc7a88198c9ee
https://doi.org/10.4049/jimmunol.155.4.2123
https://doi.org/10.4049/jimmunol.155.4.2123
Autor:
B W Winston, D W Riches
Publikováno v:
The Journal of Immunology. 155:1525-1533
Cross-linking of the dichotomous cell surface receptors for TNF-alpha (CD120a (p55) and CD120b (p75)) induces the activation of a variety of macrophage responses that mediate the role of this cell in inflammation and host defense. Although significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41221744de797d4e9fe88992c3d1ea13
https://doi.org/10.4049/jimmunol.155.3.1525
https://doi.org/10.4049/jimmunol.155.3.1525
Publikováno v:
The Journal of Immunology. 151:979-989
Macrophages maintain an essential role in orchestrating the host inflammatory response by selectively mobilizing portions of their large secretory repertoire in response to phagocytic as well as other stimuli. For example, after exposure to the infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa41cdbd1d77724d81a4fc8402dff12
https://doi.org/10.4049/jimmunol.151.2.979
https://doi.org/10.4049/jimmunol.151.2.979
Autor:
G A Underwood, D W Riches
Publikováno v:
Molecular Biology of the Cell. 3:335-347
Macrophage cytocidal activation requires the sequential impingement on the macrophage of a priming stimulus (interferon [IFN] alpha, beta, or gamma) and a triggering stimulus (such as polyinosinic acid:polycytidylic acid [poly [I:C]] or bacterial lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf747b43ff256ca192b3e4af8470d4a3
https://doi.org/10.1091/mbc.3.3.335
https://doi.org/10.1091/mbc.3.3.335
Publikováno v:
The Journal of Immunology. 145:3062-3070
Exposure of human peripheral blood neutrophils to a variety of phagocytic and soluble stimuli is known to induce the synthesis and secretion of platelet-activating factor (PAF), a unique ether-linked phospholipid. It has recently been observed in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab6b9b02e422c47fd6c45461f97ae701
https://doi.org/10.4049/jimmunol.145.9.3062
https://doi.org/10.4049/jimmunol.145.9.3062
Publikováno v:
Thorax. 65:A16-A17
Introduction TNFα is a pleiotropic cytokine that can exert opposing biological actions, either pro-inflammatory or pro-apoptotic, through interaction with its cognate receptor TNF-R1. How this balance is regulated remains to be elucidated. One possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da3e739c51b04bf5a0e979aa426e8f21
https://doi.org/10.1136/thx.2010.150912.30
https://doi.org/10.1136/thx.2010.150912.30
Publikováno v:
The Journal of biological chemistry. 274(46)
The interaction of tumor necrosis factor-alpha (TNFalpha) with its receptor sets in motion downstream signaling events including the activation of members of the mitogen-activated protein kinase (MAPK) family. In this study, we show that p42(mapk/erk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bec5fbd4db7ecdee17b2ab19776179af
https://pubmed.ncbi.nlm.nih.gov/10551865
https://pubmed.ncbi.nlm.nih.gov/10551865