Zobrazeno 1 - 10
of 79
pro vyhledávání: '"D W PURDIE"'
Autor:
D. W. Purdie, Paola Albertazzi
Publikováno v:
Maturitas. 61:214-226
Non-prescription remedies are becoming increasingly popular particularly amongst postmenopausal who in this market are the largest consumers. Phytoestrogens are a large family of plant derived molecules possessing various degrees oestrogen like activ
Publikováno v:
The Obstetrician & Gynaecologist. 5:200-203
This paper discusses new developments in the area of selective oestrogen receptor modulators and more specifically raloxifene. The most exciting of these developments is the observed reduction in the risk of breast cancer in postmenopausal women on r
Publikováno v:
Climacteric. 6:96-103
Objective: To investigate factors likely to influence adherence to hormone replacement therapy (HRT) in women known to have low bone mass. Study design: This was a prospective study of bone mineral density screening in 6282 women aged 50-54 years. Re
Autor:
W.Stuart Robertson, Elaine Gurney, Paola Albertazzi, S. A. Steel, Stephen L. Atkin, D. W. Purdie
Publikováno v:
Maturitas. 43:245-249
Raised levels of parathyroid hormones (PTH) predispose to osteoporotic fracture particularly in the elderly. The true prevalence of primary or secondary hyperparathyroidism is unknown, as PTH evaluation is not performed as a screening test in the eld
Autor:
D. W. Purdie
Publikováno v:
Climacteric. 5:236-239
Autor:
D. W. Purdie, P. Albertazzi
Publikováno v:
Climacteric. 4:194-202
The estrogens profoundly influence the growth, differentiation and function of the organs of the reproductive system such as the breast, uterus and ovary, but also have an effect on the non-reproductive tissues of the skeletal, cardiovascular and cen
Autor:
T. J. Powles, S. Eckert, K. A. Krueger, Alberto Costa, Avraham Karasik, Jane A. Cauley, Virgil Craig Jordan, Kong Wah Ng, Marc E. Lippman, S. L. Silfen, D. W. Purdie, E. L. Walls, Jan J. Stepan, J. Farrerons, Monica Morrow, Larry Norton, H. Schmitt, D. Mellstrom, D. B. Muchmore
Publikováno v:
Breast Cancer Research and Treatment. 65:125-134
Raloxifene, a selective estrogen receptor modulator approved for the prevention and treatment of postmenopausal osteoporosis, has shown a significant reduction in breast cancer incidence after 3 years in this placebo-controlled, randomized clinical t
Autor:
Curt W. Burger, John A. Eden, Jeremy Marsden, W. Atsma, D. W. Purdie, Herman A. M. Verheul, H. J T Coelingh-Bennink, Mats Hammar, Peter Kenemans
Publikováno v:
Maturitas, 36, 1-17. Elsevier Ireland Ltd
This review summarises preclinical and clinical data on effects of endogenous and exogenous estrogens on probability of breast cancer diagnosis, and on the course and efficacy of breast cancer therapies. The data indicate that higher endogenous estro
Autor:
S A Beardsworth, D W Purdie
Publikováno v:
British Journal of Clinical Pharmacology. 48:785-792
Steroids are widely dispersed throughout the biosphere where they fulfil a plethora of roles as bioregulators in both plants and animals. Indeed the simplest organism yet discovered to be utilizing them is a water mold which deploys a pheromone, oogo
Publikováno v:
Osteoporosis International. 10:52-58
Conventional hormone replacement therapy preserves bone mass predominantly by reducing bone turnover but does not exert significant anabolic skeletal effects. In contrast, high doses of estrogen have been shown to increase bone formation in animals a