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Stocking Density and Physiological Adaptive Responses of Broilers

Autor: Y. Vizzier-Thaxton, William A. Dozier, S. L. Branton, W. B. Roush, B. D. Lott, J. P. Thaxton, D. W. Miles, G. W. Morgan

Publikováno v: Poultry Science. 85:819-824

Three trials were conducted to assess the effects of stocking density on physiological adaptive responses of broilers. Male broilers were reared in floor pens under conditions similar to those used commercially in the United States. Accepted indicato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb10f70b8420e4b9faf20b429a1955b
https://doi.org/10.1093/ps/85.5.819

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13. NEW BIOLOGICAL THERAPIES FOR BREAST CANCER

Autor: T A, Plunkett, D W, Miles

Publikováno v: International Journal of Clinical Practice. 56:261-266

The exploitation of biological differences between normal and malignant cells is a logical approach to novel treatments for breast cancer. The potential targets for such therapy include the products of proto-oncogenes and oncogenes, inhibition of gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d1cc4e60513ef806adc7c98651d3f7
https://doi.org/10.1111/j.1742-1241.2002.tb11253.x

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Immunotherapy

Autor: Claude Jasmin, T. A. Plunkett, D. W. Miles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6484c36e8abdcd3697d69c202105425a
https://doi.org/10.1002/0470011610.ch24

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Safety and efficacy of the combination of trastuzumab with docetaxel for HER2-positive women with advanced breast cancer. A review of the existing clinical trials and results of the expanded access programme in the UK

Autor: K T, Papazisis, T, Habeshaw, D W, Miles

Publikováno v: International journal of clinical practice. 58(6)

Trastuzumab is a humanised monoclonal antibody against the extracellular domain of HER2 (human epidermal growth factor receptor-2) that is overexpressed in about 25% of human breast cancers. It has shown clinical benefit in HER2-positive breast cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5dabfbe09180310d84279b22d30b85f4
https://pubmed.ncbi.nlm.nih.gov/15311558

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Phase II study of docetaxel in patients with liver metastases from breast cancer. UK study group

Autor: R E, Coleman, A, Howell, S P, Eggleton, S J, Maling, D W, Miles

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology. 11(5)

Previous phase II studies of docetaxel have indicated that hepatic metastases from breast cancer respond well to first-line treatment with docetaxel. The objective of this prospective, open label phase II study therefore was specifically to evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43e5065fb5c4f51231532b841a99e4c6
https://pubmed.ncbi.nlm.nih.gov/10907946

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Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin

Autor: D, Nath, A, Hartnell, L, Happerfield, D W, Miles, J, Burchell, J, Taylor-Papadimitriou, P R, Crocker

Publikováno v: Immunology. 98(2)

In many carcinomas, infiltrating macrophages are commonly found closely associated with tumour cells but little is known concerning the nature or significance of adhesion molecules involved in these cellular interactions. Here we demonstrate in prima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::375a1f783bffa7166b36b6717018d94a
https://pubmed.ncbi.nlm.nih.gov/10610356

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Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer

Autor: M, Dowsett, C, Pfister, S R, Johnston, D W, Miles, S J, Houston, J A, Verbeek, H, Gundacker, A, Sioufi, I E, Smith

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)

This study examined whether the addition of tamoxifen to the treatment regimen of patients with advanced breast cancer being treated with the aromatase inhibitor letrozole led to any pharmacokinetic or pharmacodynamic interaction. Twelve of 17 patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a81d6f4f4f08903ffd76b8d476c779e
https://pubmed.ncbi.nlm.nih.gov/10499602

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Effect of c-erbB(2) and estrogen receptor status on survival of women with primary breast cancer treated with adjuvant cyclophosphamide/methotrexate/fluorouracil

Autor: D W, Miles, W H, Harris, C E, Gillett, P, Smith, D M, Barnes

Publikováno v: International journal of cancer. 84(4)

We have investigated the relationship between c-erbB(2) status, estrogen receptor (ER) status and outcome in 274 women with node-positive breast cancer who, following excision and axillary clearance, were randomized to receive either 6 cycles of cycl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1dc3fca6e7adacd5925f5bd20d0781d8
https://pubmed.ncbi.nlm.nih.gov/10404085

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Role of nitric oxide in tumour progression: lessons from human tumours

Autor: L L, Thomsen, D W, Miles

Publikováno v: Cancer metastasis reviews. 17(1)

Varied cellular expression and localisation of nitric oxide synthase (NOS) isoforms has been shown in human cancers, including tumours of the breast, ovary, stomach, cervix and central nervous system. Mapping of NOS expression within tumour tissue fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f6afa795a7e38c3aaaf773385c595a7
https://pubmed.ncbi.nlm.nih.gov/9544426

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