Zobrazeno 1 - 9 of 9 pro vyhledávání: '"D W McVicar"'
1
Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression
Autor: D W McVicar, Shurjo K. Sen, Stephen K. Anderson, M Cam, Hongchuan Li, Matthew McCullen
Publikováno v: Genes and immunity
The variegated expression of murine Ly49 loci has been associated with the probabilistic behavior of an upstream promoter active in immature cells, the Pro1 element. However, recent data suggest that Pro1 may be active in mature natural killer (NK) c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9216245b369f59ca022b2915312e1a11
https://doi.org/10.1038/gene.2016.31
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2
Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells
Autor: E, Townsley, G, O'Connor, C, Cosgrove, M, Woda, M, Co, S J, Thomas, S, Kalayanarooj, I-K, Yoon, A, Nisalak, A, Srikiatkhachorn, S, Green, H A F, Stephens, E, Gostick, D A, Price, M, Carrington, G, Alter, D W, McVicar, A L, Rothman, A, Mathew
Publikováno v: Clinical and Experimental Immunology
Summary Killer immunoglobulin‐like receptors (KIRs) interact with human leucocyte antigen (HLA) class I ligands and play a key role in the regulation and activation of NK cells. The functional importance of KIR–HLA interactions has been demonstra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ed26d53f2451f8091e7dd5a50cc458f
https://pubmed.ncbi.nlm.nih.gov/26439909
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3
Differential tyrosine phosphorylation of inhibitory versus activating Ly-49 receptor proteins and their recruitment of SHP-1 phosphatase
Autor: L H Mason, P Gosselin, S K Anderson, W E Fogler, J R Ortaldo, D W McVicar
Publikováno v: The Journal of Immunology. 159:4187-4196
Killer cell inhibitory receptors represent a family of p58/70-Ig-like proteins expressed on the surface of human NK cells. Engagement of class I MHC by killer cell inhibitory receptors turns off the lytic machinery of NK cells. This receptor/ligand i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e95327c8340bc82acb995e58cfd84f91
https://doi.org/10.4049/jimmunol.159.9.4187
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4
A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A
Autor: J J O'Shea, D W McVicar, D B Kuhns, J R Ortaldo
Publikováno v: The Journal of Immunology. 148:2497-2502
NK cells, CD3- large granular lymphocytes, have diverse means by which they lyse targets, including antibody-dependent cellular cytotoxicity. The low affinity receptor for the Fc portion of Ig (Fc gamma RIIIA), like the TCR, is a multimeric receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c93c6d4ba7738ab3006d2662cd3e22c
https://doi.org/10.4049/jimmunol.148.8.2497
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5
The ever-expanding Ly49 gene family: repertoire and signaling
Autor: S K, Anderson, J R, Ortaldo, D W, McVicar
Publikováno v: Immunological reviews. 181
The mouse lectin-related Ly49 family and the human killer cell Ig-like receptor (KIR) family represent structurally distinct, yet functionally analogous, class I MHC receptors that are expressed on natural killer cells and some T cells. The functiona
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b98a7a615fb09c2ac441893e8c7d03b9
https://pubmed.ncbi.nlm.nih.gov/11513154
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6
Functional association of FcepsilonRIgamma with arginine(632) of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophages
Autor: L S, Taylor, D W, McVicar
Publikováno v: Blood. 94(5)
Paired immunoglobulin-like receptors (PIR) are expressed on B cells and macrophages and include inhibitory and putative activating receptors referred to as PIR-B and PIR-A, respectively. Although PIR-B's inhibitory pathway has been described, it is u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0db43aa89387d0517003add450b437be
https://pubmed.ncbi.nlm.nih.gov/10477705
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7
DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase
Autor: D W, McVicar, L S, Taylor, P, Gosselin, J, Willette-Brown, A I, Mikhael, R L, Geahlen, M C, Nakamura, P, Linnemeyer, W E, Seaman, S K, Anderson, J R, Ortaldo, L H, Mason
Publikováno v: The Journal of biological chemistry. 273(49)
The murine Ly49 family contains nine genes in two subgroups: the inhibitory receptors (Ly49A, B, C, E, F, G2, and I) and the noninhibitory receptors (Ly49D and H). Unlike their inhibitory counterparts, Ly49D and H do not contain immunoreceptor tyrosi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1af95e86a7f4104caf12046dfe3c05e
https://pubmed.ncbi.nlm.nih.gov/9830044
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8
A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A
Autor: J J, O'Shea, D W, McVicar, D B, Kuhns, J R, Ortaldo
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 148(8)
NK cells, CD3- large granular lymphocytes, have diverse means by which they lyse targets, including antibody-dependent cellular cytotoxicity. The low affinity receptor for the Fc portion of Ig (Fc gamma RIIIA), like the TCR, is a multimeric receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52b519e1f6103ace2da26d5a48fe99e3
https://pubmed.ncbi.nlm.nih.gov/1532816
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