Zobrazeno 1 - 10
of 29
pro vyhledávání: '"D W McCourt"'
Publikováno v:
The Journal of Immunology. 154:3880-3887
The molecular nature of tissue-specific Ags involved in MHC-restricted CTL responses is as yet undefined. To determine the specificity of these peptides, their function, and their possible relationship to allograft rejection, we have utilized human k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a11e2720ec770792ec64e87870f1400
https://doi.org/10.4049/jimmunol.154.8.3880
https://doi.org/10.4049/jimmunol.154.8.3880
Publikováno v:
Proceedings of the National Academy of Sciences. 91:7588-7592
Enterokinase is a protease of the intestinal brush border that specifically cleaves the acidic propeptide from trypsinogen to yield active trypsin. This cleavage initiates a cascade of proteolytic reactions leading to the activation of many pancreati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169de853ee32d788584f7fdeb8d5319f
https://doi.org/10.1073/pnas.91.16.7588
https://doi.org/10.1073/pnas.91.16.7588
Publikováno v:
Journal of Virology. 68:5063-5073
The hepatitis C virus (HCV) H strain polyprotein is cleaved to produce at least nine distinct products: NH2-C-E1-E2-NS2-NS3-NS4A-NS4B-NS5A-NS5B-CO OH. In this report, a series of C-terminal truncations and fusion with a human c-myc epitope tag allowe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d7e0e8ccaa81c5b21eed4ebf41a428
https://doi.org/10.1128/jvi.68.8.5063-5073.1994
https://doi.org/10.1128/jvi.68.8.5063-5073.1994
Publikováno v:
Journal of Biological Chemistry. 269:6753-6758
The hemostatic functions of human von Willebrand Factor (vWF) depend on the normal assembly of disulfide-linked multimers from approximately 250-kDa subunits. Subunits initially form dimers through disulfide bonds near the COOH terminus. Dimers then
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8166e17ad31cd7400dd78369da580f70
https://doi.org/10.1016/s0021-9258(17)37439-2
https://doi.org/10.1016/s0021-9258(17)37439-2
Publikováno v:
The Journal of Experimental Medicine
The major histocompatibility complex class II molecules are composed of two polymorphic chains which, in cells normally expressing them, transiently associate with a third, nonpolymorphic molecule, the invariant chain (Ii). To determine differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2dad01f5e965041815b662f53b407c
https://doi.org/10.1084/jem.176.3.657
https://doi.org/10.1084/jem.176.3.657
Publikováno v:
The Journal of Immunology. 146:920-927
It has been proposed that invariant chain (Ii), a nonpolymorphic, transmembrane glycoprotein found in noncovalent association with Ia molecules, may function to protect the Ia Ag-binding site from association with self-peptides during Ia synthesis. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474f92b369fa5aca23060e8a4754de6e
https://doi.org/10.4049/jimmunol.146.3.920
https://doi.org/10.4049/jimmunol.146.3.920
Autor:
Vivian L. Braciale, K S Giacoletto, N R Nygard, J Gorka, D W McCourt, W T Schaiff, L R Brown, C Bono, Mary Beth Graham, M Kabeer
Publikováno v:
The Journal of Experimental Medicine
The A/Japan/57 influenza hemagglutin (HA) peptide HA 128-145, when bound by human histocompatibility leukocyte antigen-DRw11 cells, is recognized by the human CD4+ T cell clone V1. A rabbit antiserum has been raised against HA 128-145 which recognize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a052f2cb13e93a535eb2a281bffa6a0
http://europepmc.org/articles/PMC2118883
http://europepmc.org/articles/PMC2118883
Autor:
D. W. Mccourt, H Weingarten, Kathryn Akers, Jo Louise Seltzer, Arthur Z. Eisen, Gregory A. Grant
Publikováno v:
Journal of Biological Chemistry. 265:20409-20413
Type IV collagenase (gelatinase) readily cleaves denatured collagen into very small peptides. Large cyanogen bromide fragments (25 kDa) of type I collagen are degraded at the same rate as the complete alpha-chain. A number of the gelatinolytic cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b97e07fc2c7e397249b49014750e00f9
https://doi.org/10.1016/s0021-9258(17)30519-7
https://doi.org/10.1016/s0021-9258(17)30519-7
Publikováno v:
Journal of Biological Chemistry. 265:17868-17875
Phosphorylation of the human interferon-gamma (IFN gamma) receptor was studied in three cell lines of distinct lineages using radiophosphate labeling techniques. Receptors from unstimulated Colo-205 displayed a low level of constitutive phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::130be92d84ba291933241381dbc72bc5
https://doi.org/10.1016/s0021-9258(18)38244-9
https://doi.org/10.1016/s0021-9258(18)38244-9
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(5)
Binding of peptides to MHC class II Ag generates ligands for TCR of Th lymphocytes. We have identified a novel class of peptides bound to MHC class II: mannose 6- phosphate (Man-6-P) containing glycopeptides from lysosomal enzymes. These species were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa738bc936eca1543bedf3f74389f184
https://pubmed.ncbi.nlm.nih.gov/8596035
https://pubmed.ncbi.nlm.nih.gov/8596035