Zobrazeno 1 - 10
of 101
pro vyhledávání: '"D W MacGlashan"'
Publikováno v:
The Journal of Immunology. 158:5448-5454
Glucocorticoids are widely used in the therapeutic intervention of allergic diseases, affecting the function of a variety of proinflammatory cell types that participate in these disorders. These drugs have been shown to inhibit the release of histami
Autor:
A. M. DVORAK, D. W. MACGLASHAN, J. A. WARNER, L. LETOURNEAU, E. S. MORGAN, L. M. LICHTENSTEIN, S. J. ACKERMAN
Publikováno v:
Clinical Experimental Allergy. 27:452-474
Autor:
D W MacGlashan, B S Bochner, D C Adelman, P M Jardieu, A Togias, J McKenzie-White, S A Sterbinsky, R G Hamilton, L M Lichtenstein
Publikováno v:
The Journal of Immunology. 158:1438-1445
Treatment of allergic disease by decreasing circulating IgE with anti-IgE Abs is currently under clinical study. Based on previous unrelated studies, it appeared likely that Fc(epsilon)RI expression on basophils and mast cells might also be regulated
Publikováno v:
Blood. 88:4090-4101
Human basophils participating in experimentally produced contact allergy display progressive secretion of electron-dense secretory granule contents and retention of cytoplasmic granule containers in the absence of entire granule extrusion, a process
Publikováno v:
The Journal of Immunology. 157:844-850
Ligands on human basophils for the endothelial adhesion molecules intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), mucosal addressin cell adhesion molecule-1 (MAdCAM-1), and E-selectin were investigated. Adhesio
Publikováno v:
Clinical & Experimental Allergy. 26:281-294
Summary Backgrottnd Basophils arc circulaling, secretory grunulocytes that are generally considered to be end-stage cells. In one species of guinea-pigs, basophilic leucocytes have been shown to recover from stimulated secretion in short-term culture
Publikováno v:
Blood. 86:3560-3566
We examined subcellular histamine localizations in purified human basophils that were stimulated to degranulate with FMLP using an ultrastructural enzyme-affinity technique. Basophils were collected at early (0, 20 seconds, 1 minute) and late (10 min
Publikováno v:
The Journal of Immunology. 153:2600-2608
Previously, we have shown that bradykinin elicits the production of prostaglandin E2 (PGE2) in human synovial cells only after pre-exposure of the cells to IL-1. The observation that calcium ionophores, but not a variety of physiologic receptor-media
Publikováno v:
The Journal of Immunology. 153:1808-1817
IL-4 protein and mRNA have recently been detected in pure basophil cultures after stimulation. It has also been established in mixed leukocyte cultures obtained by elutriation and challenged with anti-IgE that the basophil is the only cell that makes
Autor:
M, Paterniti, D C, Kelly, J A, Eckman, P M, Sterba, R G, Hamilton, B S, Bochner, D W, Macglashan, S S, Saini
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 41(7)
Basophil histamine release (BHR) to allergen has been used as a confirmatory test to support the clinical diagnosis of allergic disease.Among subjects reporting respiratory cat allergy, we hypothesized that cat-induced BHR in vitro would predict nasa