Zobrazeno 1 - 10
of 17
pro vyhledávání: '"D W Holden"'
Autor:
Jean-Paul Latgé, Emilia Mellado, J. L. Rodriguez-Tudela, Sophie Paris, P Mol, D W Holden, Guy Dubreucq, M. Diaquin, J. Sarfati
Publikováno v:
Fungal Genetics and Biology. 38:98-109
Previous studies (Aufauvre-Brown et al., 1997; Mellado et al., 1996a,b ) have shown that only two genes of the Aspergillus fumigatus chitin synthase family, chsG and chsE, play a role in the morphogenesis of this fungal species. An A. fumigatus strai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0177bf18e7353e6b6816cd49dc38a9f9
https://doi.org/10.1016/s1087-1845(02)00516-9
https://doi.org/10.1016/s1087-1845(02)00516-9
Publikováno v:
Infection and Immunity. 62:5247-5254
To investigate the pathogenicity of Aspergillus fumigatus mutants lacking putative virulence factors, we have developed a new murine model of invasive pulmonary aspergillosis based on neutropenia, the major factor predisposing patients to this infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bf35a789b6b3fdcd8cadab7469cb65
https://doi.org/10.1128/iai.62.12.5247-5254.1994
https://doi.org/10.1128/iai.62.12.5247-5254.1994
Publikováno v:
Infection and Immunity. 62:5255-5260
To identify steps in fungal intermediary metabolism required by Aspergillus spp. during invasive pulmonary aspergillosis, we have developed murine models involving Aspergillus nidulans as the inoculum. The advantages of using A. nidulans over Aspergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be2fd01cec602f95545a66b18ab681e
https://doi.org/10.1128/iai.62.12.5255-5260.1994
https://doi.org/10.1128/iai.62.12.5255-5260.1994
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 13:318-321
The molecular epidemiology of an outbreak of invasive pulmonary aspergillosis which occurred on a renal transplantation unit was investigated. Restriction fragment length polymorphism and random amplified polymorphic DNA analyses were used to charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996ed1fb8d4a7d06ed8e5fa73bb1c763
https://doi.org/10.1007/bf01974610
https://doi.org/10.1007/bf01974610
Publikováno v:
Molecular Microbiology. 6:1663-1671
Invasive pulmonary aspergillosis, usually caused by Aspergillus fumigatus, is a life-threatening condition of immunosuppressed patients. We have created a mutant strain of this fungus that lacks an extracellular alkaline protease (AFAlp). This was ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6624b4b1675e39c4a500f430080cafca
https://doi.org/10.1111/j.1365-2958.1992.tb00891.x
https://doi.org/10.1111/j.1365-2958.1992.tb00891.x
Publikováno v:
Emergency medicine journal : EMJ. 23(12)
To determine ambulance transport rates and investigate predictors for ambulance use by patients with acute myocardial infarction (AMI) in Australia.A prospective, cross-sectional descriptive survey using structured interviews. It included patients wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad6c01bee6cc567d98fe8183eb06a05
https://pubmed.ncbi.nlm.nih.gov/17130609
https://pubmed.ncbi.nlm.nih.gov/17130609
Publikováno v:
Molecular microbiology. 40(3)
Restricted iron availability is a major obstacle to growth and survival of pathogenic bacteria during infection. In contrast to Gram-negative pathogens, little is known about how Gram-positive pathogens obtain this essential metal. We have identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf3929326d0f3dae9f61c359bb1affae
https://pubmed.ncbi.nlm.nih.gov/11359564
https://pubmed.ncbi.nlm.nih.gov/11359564
Autor:
G W, Lau, S, Haataja, M, Lonetto, S E, Kensit, A, Marra, A P, Bryant, D, McDevitt, D A, Morrison, D W, Holden
Publikováno v:
Molecular microbiology. 40(3)
Streptococcus pneumoniae remains a serious cause of morbidity and mortality in humans, but relatively little is known about the molecular basis of its pathogenesis. We used signature-tagged mutagenesis together with an analysis of S. pneumoniae genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e468230f938f257d3735bd6a8d4df048
https://pubmed.ncbi.nlm.nih.gov/11359563
https://pubmed.ncbi.nlm.nih.gov/11359563
Publikováno v:
Journal of Clinical Microbiology. 30:2991-2993
Forty-four oligonucleotide decamers were tested for their abilities to generate randomly amplified polymorphic DNA (RAPD) markers from genomic DNAs of three different isolates of Aspergillus fumigatus. Seven primers generated RAPDs that allowed the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699fa3ded4bfe229f37bd4bf4f2a7d7c
https://doi.org/10.1128/jcm.30.11.2991-2993.1992
https://doi.org/10.1128/jcm.30.11.2991-2993.1992
Publikováno v:
Molecular microbiology. 36(6)
Signature-tagged mutagenesis (STM) is a method that has been used to screen for genes required for in vivo survival of pathogenic bacteria, but has not been used to investigate a eukaryotic pathogen in an animal model of disease. We have adapted STM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24686f527a5f93e5e6dbbf3b15e3f194
https://pubmed.ncbi.nlm.nih.gov/10931287
https://pubmed.ncbi.nlm.nih.gov/10931287