Zobrazeno 1 - 10
of 48
pro vyhledávání: '"D W, Straughan"'
Autor:
D E, Leahy, R, Duncan, H J, Ahr, M K, Bayliss, A B, de Boer, F, Darvas, J H, Fentem, J R, Fry, R, Hopkins, J B, Houston, J, Karlsson, G L, Kedderis, M K, Pratten, P, Prieto, D A, Smith, D W, Straughan
Publikováno v:
Alternatives to laboratory animals : ATLA. 25(1)
Autor:
M, Balls, D W, Straughan
Publikováno v:
Developments in biological standardization. 86
The principles of humane animal experimentation proposed by RussellBurch (1959), namely, replacement, reduction, and refinement, are now commonly known as the Three Rs. These principles are clearly embodied in Article 7 of Directive 86/609/EEC. It is
Autor:
J Wallace, N A Mitchison, A M Rohas, C G Pierrepoint, J A Hickman, Paul Workman, D W Straughan, N J McNally, T C Stephens, Allan Balmain, C Rowlatt, R Raymond
Publikováno v:
CANCER AND METASTASIS REVIEW. 8:82-88
The Secretariat, UKCCCR, The Medical Research Council, 20 Park Crescent, London W1N 4AL, United Kingdom
Autor:
A Dray, D W Straughan
Publikováno v:
Journal of Pharmacy and Pharmacology. 28:400-405
Autor:
K. Krnjević, D. W. Straughan
Publikováno v:
The Journal of Physiology. 170:371-378
Publikováno v:
British Journal of Pharmacology. 38:659-666
1. The effects of strychnine on the degree of depression of neuronal firing induced by glycine, γ-aminobutyric acid (GABA) and 5-hydroxytryptamine (5-HT) have been examined quantitatively. All drugs were applied by iontophoresis to spontaneously act
Publikováno v:
The Journal of Physiology. 184:49-77
1. Since the inhibitory effect of direct or indirect cortical stimulation on cortical units can be overcome by excitation with even more L-glutamate, it is not likely to be due to an excessive depolarization. 2. Further evidence that surface stimulat
Autor:
D. W. Straughan.
Publikováno v:
Journal of Pharmacy and Pharmacology. 13:49-52
The mode of action of procaine at the neuromuscular junction has been studied in the rat isolated phrenic nerve diaphragm preparation. Procaine had no effect on the response to indirect stimulation in concentrations below 8 × 10−5. But 2 × 10−5
Autor:
Mirjana Randić, D. W. Straughan
Publikováno v:
The Journal of Physiology. 173:130-148
Publikováno v:
British Journal of Pharmacology. 49:37-51
1. By the use of microiontophoretic techniques, quantitative estimates were obtained of the depressant effects of γ-aminobutyric acid (GABA) on single feline cortical neurones. 2. Picrotoxin, bicuculline, strychnine, (+)-tubocurarine, penicillin and