Zobrazeno 1 - 10 of 18 pro vyhledávání: '"D W, Schulz"'
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Chronic administration of the selective corticotropin-releasing factor 1 receptor antagonist CP-154,526: behavioral, endocrine and neurochemical effects in the rat
Autor: L, Arborelius, K H, Skelton, K V, Thrivikraman, P M, Plotsky, D W, Schulz, M J, Owens
Publikováno v: The Journal of pharmacology and experimental therapeutics. 294(2)
Corticotropin-releasing factor 1 (CRF(1)) receptor antagonists may represent a novel group of drugs for the pharmacotherapy of depression and/or anxiety disorders. We have investigated the behavioral, endocrine, and neurochemical effects of chronic a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d0f9e7add7a288585e52b8594e81abd
https://pubmed.ncbi.nlm.nih.gov/10900236
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3
Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity
Autor: T F, Seeger, P A, Seymour, A W, Schmidt, S H, Zorn, D W, Schulz, L A, Lebel, S, McLean, V, Guanowsky, H R, Howard, J A, Lowe
Publikováno v: The Journal of pharmacology and experimental therapeutics. 275(1)
Ziprasidone (CP-88,059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas the compound is a dopamine antagonist in vitro and in vivo, its
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f0136d69e8f80db8e60dd3baa418c0e
https://pubmed.ncbi.nlm.nih.gov/7562537
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5
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole
Autor: J E, Macor, C A, Burkhart, J H, Heym, J L, Ives, L A, Lebel, M E, Newman, J A, Nielsen, K, Ryan, D W, Schulz, L K, Torgersen
Publikováno v: Journal of medicinal chemistry. 33(8)
The synthesis and in vitro and in vivo characteristics of 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one (1, CP-93,129) are described. This rotationally restricted phenolic analogue of RU-24,969 is a potent (15 nM) and selective (200x vs t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99ecc0581e109cbcd1fac527d1aeeba
https://pubmed.ncbi.nlm.nih.gov/2374139
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6
The distribution of the components of the cyclic GMP cycle in retina
Autor: S J, Berger, G W, DeVries, J G, Carter, D W, Schulz, P N, Passonneau, O H, Lowry, J A, Ferrendelli
Publikováno v: The Journal of biological chemistry. 255(7)
Frozen sections of retinas from rabbit (mostly rods), ground squirrel (mostly cones), and monkey (mixed rods and cones) were freeze dried, and samples from all the discrete layers analyzed for the enzymes which form cyclic GMP and subsequently conver
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e17cad4f13a51ae066b39afea32cdb7f
https://pubmed.ncbi.nlm.nih.gov/6102093
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9
SCH23390 effects on apomorphine-induced responses of nigral dopaminergic neurons
Autor: T C, Napier, B S, Givens, D W, Schulz, B S, Bunney, G R, Breese, R B, Mailman
Publikováno v: The Journal of pharmacology and experimental therapeutics. 236(3)
SCH23390 is a dopamine antagonist which has a high affinity for D1-like dopaminergic receptors. Receptor binding studies demonstrated significant levels of specific SCH23390 binding within nigral tissue. Therefore, electrophysiological experiments we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cbe382a949c981c081e9822bbe83a6dd
https://pubmed.ncbi.nlm.nih.gov/3512819
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