Zobrazeno 1 - 10
of 243
pro vyhledávání: '"D W, Piper"'
Autor:
Tahlia L. Fulton, Joshua N. Johnstone, Jing J. Tan, Krithika Balagopal, Amy Dedman, Andrea Y. Chan, Travis K. Johnson, Christen K. Mirth, Matthew D. W. Piper
Publikováno v:
Open Biology, Vol 14, Iss 8 (2024)
Nutrition and resilience are linked, though it is not yet clear how diet confers stress resistance or the breadth of stressors that it can protect against. We have previously shown that transiently restricting an essential amino acid can protect Dros
Externí odkaz:
https://doaj.org/article/689d12d7c11448ec965f1ea5f2fa152b
Autor:
Felipe Martelli, Annelise Quig, Sarah Mele, Jiayi Lin, Tahlia L. Fulton, Mia Wansbrough, Christopher K. Barlow, Ralf B. Schittenhelm, Travis K. Johnson, Matthew D. W. Piper
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Drosophila melanogaster is unique among animal models because it has a fully defined synthetic diet available to study nutrient-gene interactions. However, use of this diet is limited to adult studies due to impaired larval development and s
Externí odkaz:
https://doaj.org/article/1402184d5678404da39f83a9a59792eb
Autor:
Hina Kosakamoto, Fumiaki Obata, Junpei Kuraishi, Hide Aikawa, Rina Okada, Joshua N. Johnstone, Taro Onuma, Matthew D. W. Piper, Masayuki Miura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Methionine restriction (MetR) extends lifespan in various organisms, but its mechanistic understanding remains incomplete. Whether MetR during a specific period of adulthood increases lifespan is not known. In Drosophila, MetR is reported to
Externí odkaz:
https://doaj.org/article/ba329a8b8284401989c9411852fd6206
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010635 (2023)
Dietary nutrient composition is essential for shaping important fitness traits and behaviours. Many organisms are protein limited, and for Drosophila melanogaster this limitation manifests at the level of the single most limiting essential Amino Acid
Externí odkaz:
https://doaj.org/article/fcdcb4b4592e4e7fb21e1efe35693b3a
Publikováno v:
Open Biology, Vol 12, Iss 12 (2022)
Dietary interventions that restrict protein intake have repeatedly been shown to offer beneficial health outcomes to the consumer. Benefits such as increased stress tolerance can be observed when individual amino acids are restricted, thus mimicking
Externí odkaz:
https://doaj.org/article/60b6fe7ced104266a82df136e6570ad5
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Nutrition shapes a broad range of life-history traits, ultimately impacting animal fitness. A key fitness-related trait, female fecundity is well known to change as a function of diet. In particular, the availability of dietary protein is one of the
Externí odkaz:
https://doaj.org/article/a973631237c245368aea3383e381ba93
Autor:
Yann W. Yap, Patricia M. Rusu, Andrea Y. Chan, Barbara C. Fam, Andreas Jungmann, Samantha M. Solon-Biet, Christopher K. Barlow, Darren J. Creek, Cheng Huang, Ralf B. Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D. W. Piper, Mathias Heikenwälder, Stephen J. Simpson, Stefan Bröer, Sofianos Andrikopoulos, Oliver J. Müller, Adam J. Rose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Dietary protein dilution, where protein is reduced and replaced by other nutrient sources without caloric restriction, promotes metabolic health via the hepatokine Fgf21. Here, the authors show that essential amino acids threonine and tryptophan are
Externí odkaz:
https://doaj.org/article/36856bb21e41464a998b62244a235694
Autor:
Adam J. Dobson, Xiaoli He, Eric Blanc, Ekin Bolukbasi, Yodit Feseha, Mingyao Yang, Matthew D. W. Piper
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 4, Iss 1, Pp 1-8 (2018)
Author summary Ageing human populations present a huge societal challenge, providing motivation to find ways to improve health in old age. Dietary restriction (DR), is one way to improve late-life health of animals from worms to mammals, and perhaps
Externí odkaz:
https://doaj.org/article/5a6103376c014385858bcf0015323dc3
Autor:
Matthew D. W. Piper, Brooke Zanco, Carla M. Sgrò, Margo I. Adler, Christen K. Mirth, Russell Bonduriansky
Publikováno v:
The FEBS Journal. 290:1725-1734
Reducing overall food intake, or lowering the proportion of protein relative to other macronutrients, can extend the lifespan of diverse organisms. A number of mechanistic theories have been developed to explain this phenomenon, mostly assuming that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f2d62a9ed46c40c229d5ce0132bf65
https://doi.org/10.1111/febs.16463
https://doi.org/10.1111/febs.16463
Autor:
Hina Kosakamoto, Fumiaki Obata, Junpei Kuraishi, Hide Aikawa, Rina Okada, Joshua N. Johnstone, Taro Onuma, Matthew D. W. Piper, Masayuki Miura
Methionine restriction (MetR) extends lifespan in various organisms, but its mechanistic understanding remains incomplete. Whether MetR during a specific period of adulthood increases lifespan is not shown. InDrosophila, MetR is reported to extend li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcaf614ff55f7e5accdf1527ebb66e13
https://doi.org/10.1101/2023.03.15.532514
https://doi.org/10.1101/2023.03.15.532514
