Výsledky vyhledávání

An attempt to detect changes in the Sun's luminosity during the last glaciation by applying the Poynting-Robertson effect to cosmic spherules from a dated deep-sea core

Autor: D. W. Parkin

Publikováno v: Monthly Notices of the Royal Astronomical Society. 307:518-528

In previous papers by Parkin, Sullivan & Bull and Parkin, the Poynting–Robertson effect was applied to iron-type cosmic spherules, from two North Pacific cores, in the hope of proving that cosmic spherules existed as round bodies in space. It was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3714c6bf54718ff4e1d52f37e99c5d2
https://doi.org/10.1046/j.1365-8711.1999.02619.x

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Pattern of ophthalmological accidents and emergencies presenting to hospitals

Autor: R F Gillie, D W Parkin, Raj Bhopal, K H Han

Publikováno v: Journal of Epidemiology & Community Health. 47:382-387

STUDY OBJECTIVE--To investigate the numbers and characteristics of patients with ophthalmological accidents and emergencies presenting to hospitals. DESIGN--Prospective survey over eight weeks. SETTING--Two general and one ophthalmic accident and eme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549ff6364d7b6185ca26e01aadd252a8
https://doi.org/10.1136/jech.47.5.382

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Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax

Autor: W, Versées, K, Decanniere, R, Pellé, J, Depoorter, E, Brosens, D W, Parkin, J, Steyaert

Publikováno v: Journal of molecular biology. 307(5)

The purine salvage pathway of parasitic protozoa is currently considered as a target for drug development because these organisms cannot synthesize purines de novo. Insight into the structure and mechanism of the involved enzymes can aid in the devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f27d940cb3ce95d20cf4aff5b5bd9971
https://pubmed.ncbi.nlm.nih.gov/11292348

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Molecular cloning and expression of a purine-specific N-ribohydrolase from Trypanosoma brucei brucei. Sequence, expression, and molecular analysis

Autor: R, Pellé, V L, Schramm, D W, Parkin

Publikováno v: The Journal of biological chemistry. 273(4)

N-Ribohydrolases, including the inosine-adenosine-guanosine-preferring (IAG) nucleoside hydrolase, have been proposed to be involved in the nucleoside salvage pathway of protozoan parasites and may constitute rational therapeutic targets for the trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0aef9cd1a94d614f808d7d8736c6b130
https://pubmed.ncbi.nlm.nih.gov/9442052

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Purine-specific nucleoside N-ribohydrolase from Trypanosoma brucei brucei. Purification, specificity, and kinetic mechanism

Autor: D W, Parkin

Publikováno v: The Journal of biological chemistry. 271(36)

Trypanosomes have no de novo purine biosynthesis and thus depend upon salvage pathways to obtain purines for their metabolic pathways and for the biosynthesis of nucleic acids. An inosine-adenosine-guanosine preferring nucleoside hydrolase (IAG-nucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e954250d42c9c1d1187da1817e2f8ce
https://pubmed.ncbi.nlm.nih.gov/8702965

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Thresholds for treatment in cataract surgery

Autor: A. Mordue, C. Baxter, M. Stewart, D. W. Parkin, G. Fawcett

Publikováno v: Journal of public health medicine. 16(4)

BACKGROUND The aim of the study was to identify the criteria used by ophthalmologists when assessing patients who may require cataract surgery, examine the extent of variation in their application and explore their relationship with current patterns

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4326e072c23d925aee9108f0a5597d13
https://pubmed.ncbi.nlm.nih.gov/7880569

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Authors have rights too

Autor: R S Bhopal, D W Parkin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bce4119d696b916ecac401187caefcd
https://europepmc.org/articles/PMC1677119/

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Nucleoside hydrolase from Crithidia fasciculata. Metabolic role, purification, specificity, and kinetic mechanism

Autor: D W, Parkin, B A, Horenstein, D R, Abdulah, B, Estupiñán, V L, Schramm

Publikováno v: The Journal of biological chemistry. 266(31)

Crithidia fasciculata cells grown on complex medium with added [8-14C, 5'-3H]inosine or [8-14C,5'-3H]adenosine metabolize greater than 50% of the salvaged nucleosides through a pathway involving N-glycoside bond cleavage. Cell extracts contain a subs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42214ca3ead5993f8489643bae6c5261
https://pubmed.ncbi.nlm.nih.gov/1939115

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