Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D W, McVicar"'
Publikováno v:
Genes and immunity
The variegated expression of murine Ly49 loci has been associated with the probabilistic behavior of an upstream promoter active in immature cells, the Pro1 element. However, recent data suggest that Pro1 may be active in mature natural killer (NK) c
Autor:
E, Townsley, G, O'Connor, C, Cosgrove, M, Woda, M, Co, S J, Thomas, S, Kalayanarooj, I-K, Yoon, A, Nisalak, A, Srikiatkhachorn, S, Green, H A F, Stephens, E, Gostick, D A, Price, M, Carrington, G, Alter, D W, McVicar, A L, Rothman, A, Mathew
Publikováno v:
Clinical and Experimental Immunology
Summary Killer immunoglobulin‐like receptors (KIRs) interact with human leucocyte antigen (HLA) class I ligands and play a key role in the regulation and activation of NK cells. The functional importance of KIR–HLA interactions has been demonstra
Publikováno v:
The Journal of Immunology. 159:4187-4196
Killer cell inhibitory receptors represent a family of p58/70-Ig-like proteins expressed on the surface of human NK cells. Engagement of class I MHC by killer cell inhibitory receptors turns off the lytic machinery of NK cells. This receptor/ligand i
Publikováno v:
The Journal of Immunology. 148:2497-2502
NK cells, CD3- large granular lymphocytes, have diverse means by which they lyse targets, including antibody-dependent cellular cytotoxicity. The low affinity receptor for the Fc portion of Ig (Fc gamma RIIIA), like the TCR, is a multimeric receptor
Publikováno v:
Immunological reviews. 181
The mouse lectin-related Ly49 family and the human killer cell Ig-like receptor (KIR) family represent structurally distinct, yet functionally analogous, class I MHC receptors that are expressed on natural killer cells and some T cells. The functiona
Autor:
L S, Taylor, D W, McVicar
Publikováno v:
Blood. 94(5)
Paired immunoglobulin-like receptors (PIR) are expressed on B cells and macrophages and include inhibitory and putative activating receptors referred to as PIR-B and PIR-A, respectively. Although PIR-B's inhibitory pathway has been described, it is u
Autor:
D W, McVicar, L S, Taylor, P, Gosselin, J, Willette-Brown, A I, Mikhael, R L, Geahlen, M C, Nakamura, P, Linnemeyer, W E, Seaman, S K, Anderson, J R, Ortaldo, L H, Mason
Publikováno v:
The Journal of biological chemistry. 273(49)
The murine Ly49 family contains nine genes in two subgroups: the inhibitory receptors (Ly49A, B, C, E, F, G2, and I) and the noninhibitory receptors (Ly49D and H). Unlike their inhibitory counterparts, Ly49D and H do not contain immunoreceptor tyrosi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(8)
NK cells, CD3- large granular lymphocytes, have diverse means by which they lyse targets, including antibody-dependent cellular cytotoxicity. The low affinity receptor for the Fc portion of Ig (Fc gamma RIIIA), like the TCR, is a multimeric receptor
Publikováno v:
Neurosurgery. 23:725