Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D W, Gil"'
Publikováno v:
British Journal of Pharmacology. 153:769-774
Background and purpose: The most common preclinical models of neuropathic pain involve surgical ligation of sensory nerves, which is especially difficult in mice. Transient models of chemically sensitized allodynia are potentially useful for rapidly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a3d481f30657d792809e077cb65397
https://doi.org/10.1038/sj.bjp.0707412
https://doi.org/10.1038/sj.bjp.0707412
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 28(3)
Background Changes in central pain modulation have been implicated in generalized pain syndromes such as irritable bowel syndrome (IBS). We have previously demonstrated that reduced descending inhibition unveils a role of sympathoneuronal outflow in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96c7cea1c4923597d467f861df5839c
https://pubmed.ncbi.nlm.nih.gov/26670784
https://pubmed.ncbi.nlm.nih.gov/26670784
Autor:
Achim H.-P. Krauss, Charles E. Protzman, Licheng Shi, R. M. Burk, R. Chen, Steven W. Andrews, George Sachs, H. T. T. Dinh, Heather A. Krauss, Karen M. Kedzie, A.M. Bogardus, L. J. Kaplan, Michael B. Roof, M. E. Garst, Ming Fai Chan, Larry A. Wheeler, R. A. Ross, John W. Regan, Todd S. Gac, June Chen, Kristen L. Pierce, D.F. Woodward, D. W. Gil
Publikováno v:
British Journal of Pharmacology. 130:1933-1943
Replacement of the carboxylic acid group of PGF(2alpha) with the non-acidic substituents hydroxyl (-OH) or methoxy (-OCH(3)) resulted in an unexpected activity profile. Although PGF(2alpha) 1-OH and PGF(2alpha) 1-OCH(3) exhibited potent contractile e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4db77a4e459e159e2b98cf72dd45616b
https://doi.org/10.1038/sj.bjp.0703462
https://doi.org/10.1038/sj.bjp.0703462
Publikováno v:
Scopus-Elsevier
Voltage-sensitive sodium channels play a key role in nerve cells where they are responsible for the increase in sodium permeability during the rising phase of action potentials. In Drosophila melanogaster a subset of temperature-sensitive paralytic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343e2c9518f1662b8f08078fb9f370fb
https://doi.org/10.1093/genetics/139.4.1679
https://doi.org/10.1093/genetics/139.4.1679
Autor:
M. E. Garst, Samuel J. Gillett, Larry A. Wheeler, Taghreed Arefieg, Tae K. Song, Roshantha A.S. Chandraratna, S. Vuligonda, J. Attard, D. W. Gil
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c49bd4aa8016dcbf16fc8dc94f0a39b
https://doi.org/10.1002/chin.199530275
https://doi.org/10.1002/chin.199530275
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(1)
Recent studies have suggested that alpha(2)-adrenergic agonists prevent neuronal cell death in a number of animal models, although the mechanism of alpha(2)-neuroprotection remains unclear. In a retinal ischemia model, the alpha(2)-specific agonist b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8170e75c8239fed61c2e6d663ef33fb
https://pubmed.ncbi.nlm.nih.gov/11123383
https://pubmed.ncbi.nlm.nih.gov/11123383
Publikováno v:
Investigative ophthalmologyvisual science. 38(7)
To determine the relative levels of the five muscarinic receptor subtypes in the anterior segment of the human eye.Antisera selective for each of the five muscarinic receptor proteins were incubated with [3H]-QNB bound receptors solubilized from huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9af3effef13b3cd3f0e49e7fda7d9c1c
https://pubmed.ncbi.nlm.nih.gov/9191607
https://pubmed.ncbi.nlm.nih.gov/9191607
Publikováno v:
Investigative ophthalmologyvisual science. 36(13)
To develop antibodies that selectively recognize each of the alpha 2-adrenergic receptor (AR) subtypes and to determine the expression and localization of these subtypes in the anterior segment of the human eye.Recent studies have shown that there ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3dad9a6ba3801f6522b41047347970ce
https://pubmed.ncbi.nlm.nih.gov/7499095
https://pubmed.ncbi.nlm.nih.gov/7499095
Autor:
John E. Donello, Steven W. Andrews, A.M. Bogardus, E. Runde, Alexander B. Kharlamb, D.F. Woodward, J. W. Regan, J.A. Burke, D. W. Gil, Kristen L. Pierce, Karen M. Kedzie, C.E. Fairbairn
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 11(3)
The cloning of the genes that encode for prostaglandin (PG) receptors has resolved much of the complexity and controversy in this area by confirming the classification proposed by Coleman, et al. Two issues that remained unresolved were (1) the inabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f417ba8e0b8e59d93c23a35925ce2868
https://pubmed.ncbi.nlm.nih.gov/8590276
https://pubmed.ncbi.nlm.nih.gov/8590276
Autor:
J W, Regan, T J, Bailey, D J, Pepperl, K L, Pierce, A M, Bogardus, J E, Donello, C E, Fairbairn, K M, Kedzie, D F, Woodward, D W, Gil
Publikováno v:
Molecular pharmacology. 46(2)
A cDNA that when expressed has the binding and functional characteristics of the pharmacologically defined EP2 prostaglandin (PG) receptor [Cardiovasc. Drug Rev. 11:165-179 (1993)] has been cloned from a human placenta library. This clone, known as H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7216717a909f38e635ae0530afda86c7
https://pubmed.ncbi.nlm.nih.gov/8078484
https://pubmed.ncbi.nlm.nih.gov/8078484