Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D W, Dunne"'
Publikováno v:
The Journal of Immunology. 163:4976-4984
During infection with Schistosoma mansoni, NO production increases following the deposition of parasite eggs in the liver. In wild-type C57BL/6 mice, NO levels peak during the sixth week of infection and are subsequently down-regulated. Inducible NO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f80c3fbe39d6fc7e300277d449f2f1
https://doi.org/10.4049/jimmunol.163.9.4976
https://doi.org/10.4049/jimmunol.163.9.4976
Publikováno v:
European journal of immunology. 31(5)
Aged mice have various defects in their immune system. We report that following in vivo challenge with type 2 cytokine-inducing Schistosoma mansoni eggs, aged mice fail to produce type 2 cytokines and also have impaired antigen-specific antibody prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2e556edd98e5f5056613d0b1e5360a0
https://pubmed.ncbi.nlm.nih.gov/11465106
https://pubmed.ncbi.nlm.nih.gov/11465106
Autor:
P G, Fallon, D W, Dunne
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(7)
The granuloma that surrounds the Schistosoma mansoni egg is the cause of pathology in murine schistosomiasis, and its formation is driven by egg Ag-stimulated type 1 and type 2 cytokines. To determine the role of egg-driven immune responses during sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8d25c1c4ebb05fbd3fa05844cefc19b
https://pubmed.ncbi.nlm.nih.gov/10201937
https://pubmed.ncbi.nlm.nih.gov/10201937
Publikováno v:
European journal of immunology. 29(3)
Killing of Schistosoma mansoni larvae by human eosinophils via antibody-dependent cell-mediated cytotoxicity (ADCC) mechanisms requires adherence between effector cells and parasite targets. The role of adhesion molecules in this mechanism was invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb6c0a5d661db2f82d95b4ee95b6e52b
https://pubmed.ncbi.nlm.nih.gov/10092082
https://pubmed.ncbi.nlm.nih.gov/10092082
Publikováno v:
European journal of immunology. 28(4)
CD4+ and CD8+ T cells can be divided based on the cytokines that they secrete into type 1 (Th1, Tc1) and type 2 (Th2, Tc2) subsets. Schistosoma mansoni infection in mice is characterized by a type 2-dominated response. We have used intracellular cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e89d92692203c81bf40db826fc2d56f6
https://pubmed.ncbi.nlm.nih.gov/9565381
https://pubmed.ncbi.nlm.nih.gov/9565381
Publikováno v:
Cytokine. 6:581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9761e3b210889d1b9bc77f7427fa679c
https://doi.org/10.1016/1043-4666(94)90325-5
https://doi.org/10.1016/1043-4666(94)90325-5
Autor:
D. W. Dunne, Quentin D. Bickle
Publikováno v:
Parasitology. 94:255-268
SUMMARYAntisera were produced by immunizing rabbits with either a trichloroacetic acid-soluble fraction, or a high molecular weight (Mr) fraction ofSchistosoma mansoniSEA (a salinesoluble fraction of homogenized egg). Both of these sera reacted monos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c510e95ae0307b262b0583421b7ccbbb
https://doi.org/10.1017/s0031182000053932
https://doi.org/10.1017/s0031182000053932
Autor:
D. W. Dunne, J. D. Dargie, G. S. Nelson, A. R. Dobinson, Quentin D. Bickle, M. F. Hussein, E. R. James, C. I. Berry, Martin G. Taylor
Publikováno v:
Europe PubMed Central
Border Leicester X Suffolk sheep infected with a strain of S. mattheei maintained in hamsters do not develop the same pathological changes as Romney Marsh sheep infected with the same strain of parasite before hamster passage. To determine the cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869343e16f58d90ad2ecb3380a8be192
https://doi.org/10.1017/s0022149x00007690
https://doi.org/10.1017/s0022149x00007690
Publikováno v:
The Journal of Immunology. 142:4422-4427
Although IgG antibodies and eosinophils have been shown to kill schistosomula of Schistosoma mansoni in vitro, very little data exist that describe the role of each IgG antibody isotype in this event. This study was designed to test the role of each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fda69fb5926284590766d0a45f2ffd9
https://doi.org/10.4049/jimmunol.142.12.4422
https://doi.org/10.4049/jimmunol.142.12.4422
Publikováno v:
Europe PubMed Central
Irradiated cercariae, irradiated schistosomula, or hcterologous infections were used to vaccinate sheep against Schistosoma mattheei infection. In the first experiment four doses of I04 S. mattheei cercariae irradiated at 6Kr were administered to she
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe641a94ee901ab902a98287b7ddb26
https://doi.org/10.1017/s0022149x00028753
https://doi.org/10.1017/s0022149x00028753