Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D W, Brann"'
Autor:
D. W. Brann
Publikováno v:
Endocrine Reviews. 18:678-700
Autor:
K M, Dhandapani, D W, Brann
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 78(3)
The preovulatory surge of gonadotropin releasing hormone (GnRH) is essential for mammalian reproduction. Recent work has implicated the neurotransmitters glutamate and nitric oxide as having a key role in this process. Large concentrations of glutama
Publikováno v:
Biology of reproduction. 62(6)
The purpose of this study was to identify factors from astrocytes that can regulate LHRH neurosecretion. Exposure of LHRH-secreting (GT1-7) cells to conditioned media (CM) from C6 glial cells and hypothalamic astrocytes (HA) stimulated LHRH release.
Publikováno v:
Endocrinology. 140(10)
In a previous publication we provided evidence of a novel neuronal pathway for the control of GnRH secretion by bradykinin. The action of bradykinin appeared to be exerted through the bradykinin B2 receptor. In this study we demonstrated that the bra
Publikováno v:
Neuroendocrinology. 66(4)
Recent work has demonstrated that glutamate functions as a major transmitter involved in the regulation of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion in female animals, although the specific receptors and mechanisms
Publikováno v:
Neuroendocrinology. 63(5)
Determination of mRNA levels of specific genes is becoming increasingly important as a measure of gene expression. With the recent advent of RT-PCR, the sensitivity for mRNA determination has been increased dramatically, and this technique is becomin
Publikováno v:
Neuroendocrinology. 62(6)
The progesterone-induced LH surge in the estrogen-primed rat is thought to be mediated through interneurons since LHRH neurons reportedly lack steroid receptors. Along these lines, glutamate and gamma-aminobutyric acid (GABA) neurons are considered t
Publikováno v:
Neuroendocrinology. 62(2)
N-methyl-D-aspartate (NMDA), a specific agonist of the NMDA-type glutamate receptor, has been shown to stimulate the release of several anterior pituitary hormones when administered in vivo. The primary site of action of NMDA has been suggested to be
Publikováno v:
Biology of reproduction. 47(6)
Ovulation has been noted for some time to bear a remarkable similarity to an inflammatory response. One of the principal components that is activated and helps mediate the events during an inflammatory response is the kinin system. Therefore, the pur
Autor:
D W, Brann, V B, Mahesh
Publikováno v:
Biology of reproduction. 44(6)
Progesterone and certain corticosteroids, such as deoxycorticosterone (DOC) and triamcinolone acetonide (TA), can stimulate gonadotropin surges in rats. The mechanism of these steroids could involve a pituitary or hypothalamic site of action, or both