Zobrazeno 1 - 10
of 75
pro vyhledávání: '"D W, Alberts"'
Publikováno v:
Free Radical Research Communications. 17:263-269
Our previous studies showed that exposure of rats to limited periods of cigarette smoke resulted in more severe myocardial damage when their hearts were subjected to myocardial ischaemia/reperfusion. The aim of this study was to determine whether sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21252705b9e2f7ac9226b76bde23e640
https://doi.org/10.3109/10715769209079518
https://doi.org/10.3109/10715769209079518
Publikováno v:
Basic Research in Cardiology. 87:393-399
It is suggested that passive smoking or smoke-exposure increase the risk of coronary heart disease. The same mechanisms as active smoking might play a role. The aim of this study was to determine whether exposure to smoke aggravated ischaemia/reperfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f326bbf10e1cf3d76a76bc932748c4
https://doi.org/10.1007/bf00796524
https://doi.org/10.1007/bf00796524
Publikováno v:
Free Radical Research Communications. 15:151-157
Anaesthetic drugs can induce reversible as well as irreversible changes in cell membranes and intracellular proteins as well as lipid peroxidation in the liver. Low molecular weight iron species (LMWI) can by their catalytic activity contribute to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0232a2387d7b256d8629ae3882631d8a
https://doi.org/10.3109/10715769109049135
https://doi.org/10.3109/10715769109049135
Publikováno v:
Journal of the South African Veterinary Association. 67(1)
Several experimental effects due to wood-derived bedding have been reported. Female Sprague Dawley rats were kept on pine shavings, eucalyptus pulp, vermiculite and in wire-bottomed cages without bedding for 14 days whereafter normal values for the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa28f17d407b4e2fdcf8f94a7171219d
https://pubmed.ncbi.nlm.nih.gov/8786613
https://pubmed.ncbi.nlm.nih.gov/8786613
Publikováno v:
Research communications in molecular pathology and pharmacology. 85(1)
This study was undertaken to investigate whether prior antioxidant supplementation had a beneficial effect on subsequent myocardial ischemic/reperfusion injury and whether addition of ascorbate during ischemia/reperfusion had any effect. Supplementat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a69b34ede2957a4d254b18849f9dd929
https://pubmed.ncbi.nlm.nih.gov/7953193
https://pubmed.ncbi.nlm.nih.gov/7953193
Autor:
S J, Grossman, E G, Herold, J M, Drey, D W, Alberts, D R, Umbenhauer, D H, Patrick, D, Nicoll-Griffith, N, Chauret, J A, Yergey
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(6)
It has previously been shown that Verlukast is converted to Verlukast dihydrodiol in microsomes from beta-naphthoflavone (BNF)-treated, but not uninduced Swiss Webster mice and Sprague-Dawley rats. We have examined the involvement of CYP1A1 in this r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::721c8ecd07785ec50095f0db3cec2e28
https://pubmed.ncbi.nlm.nih.gov/7905381
https://pubmed.ncbi.nlm.nih.gov/7905381
Publikováno v:
Basic research in cardiology. 87(1)
Reperfusion of ischaemic myocardium is necessary to sustain tissue viability (without it the tissue becomes necrotic), but reperfusion, on the other hand, can damage cells which have survived ischaemia. There is now considerable evidence that oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57010a4712678e267ca42d551a92fbc1
https://pubmed.ncbi.nlm.nih.gov/1567353
https://pubmed.ncbi.nlm.nih.gov/1567353
Autor:
G D, Hoke, F L, McCabe, L F, Faucette, J O, Bartus, C M, Sung, B D, Jensen, J R, Heys, G F, Rush, D W, Alberts, R K, Johnson
Publikováno v:
Molecular pharmacology. 39(1)
Bis(diphenylphosphine)ethane (DPPE) and its gold coordination complexes have demonstrated antitumor activity in transplantable tumor models. This report describes the development of a P388 cell line (P388/DPPEc) that is resistant to DPPE and its anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c94eeef59de6aa9401d55e04f2e64056
https://pubmed.ncbi.nlm.nih.gov/1898982
https://pubmed.ncbi.nlm.nih.gov/1898982
Autor:
G F, Rush, P F, Smith, D W, Alberts, C K, Mirabelli, R M, Snyder, S T, Crooke, J, Sowinski, H B, Jones, P J, Bugelski
Publikováno v:
Toxicology and applied pharmacology. 90(3)
Triethylphosphine gold complexes are effective therapeutic agents used for the treatment of rheumatoid arthritis. Many of those molecules are also highly cytotoxic in vitro and can inhibit DNA and protein synthesis. Preliminary experiments have indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0018527a5eb0bea1a97855cff3af505f
https://pubmed.ncbi.nlm.nih.gov/3660408
https://pubmed.ncbi.nlm.nih.gov/3660408
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 249(3)
SKF 104524 (bis-[1,2 bis(diphenylphosphino)-ethane]gold(l) lactate) [( Au(dppe)2]+) is an experimental antineoplastic agent that is hepatotoxic in vivo in the dog as well as highly cytotoxic to isolated canine hepatocytes in vitro. Preliminary studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c1e3f56697f8aaa6b9041e488e55a9f
https://pubmed.ncbi.nlm.nih.gov/2732955
https://pubmed.ncbi.nlm.nih.gov/2732955