Zobrazeno 1 - 10
of 23
pro vyhledávání: '"D V Gold"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(10)
Radioimmunotherapy studies using (131)I-PAM4 have demonstrated significant antitumor effects in mice bearing human pancreatic cancer xenografts. For several reasons (90)Y has been proposed as a more effective radionuclide for radioimmunotherapy of pa
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
Multiple myeloma (MM) is the second most common hematological cancer in the United States. It is typically incurable, even with myeloablative chemotherapy and stem-cell transplantation. The epithelial mucin-1 (MUC1) glycoprotein is expressed by norma
Publikováno v:
International journal of cancer. 71(4)
We examined the therapeutic efficacy of 131I-labeled murine monoclonal antibody (MAb) PAM4 against human pancreatic cancers carried as xenografts in athymic nude mice. Animals bearing the CaPan1 tumor (0.2 cm3) were either untreated or were given, 13
Autor:
D. Bacciardi, Franco Mosca, L Di Luca, D. Balestracci, C. Bonino, R. M. Sharkey, P. C. Giulianotti, Giuliano Mariani, D. Campani, D. V. Gold, N. Molea, Paolo Viacava, L. Bodei, D. M. Goldenberg, E. Lazzeri, P. A. Salvadori
Publikováno v:
Radioactive Isotopes in Clinical Medicine and Research ISBN: 9783034877749
In this study we evaluated the biodistribution and potential usefulness for tumor immunoscintigraphy of two recently developed monoclonal antibodies (MoAbs), termed AR-3 and PAM4, in patients with pancreatic cancer. The two MoAbs were labeled with 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0481a55d37c2212c04fb34d699214cb
https://doi.org/10.1007/978-3-0348-7772-5_65
https://doi.org/10.1007/978-3-0348-7772-5_65
Publikováno v:
Cancer research. 55
To resemble the clinical presentation of pancreatic cancer in an animal model more closely, we developed an orthotopic xenograft of CaPan-1 human pancreatic cancer in athymic nude mice. Within 3 weeks after implantation into the body and head of the
Publikováno v:
Cancer research. 55(5)
We have examined the ability of murine monoclonal antibody PAM4, directed against a pancreatic cancer-derived mucin, to target human pancreatic cancers carried as xenografts in athymic nude mice. Four tumor lines were used representing the range of e
Autor:
P. A. Salvadori, P. C. Giulianotti, G. Fornaciari, D. Bacciardi, F. Mosca, D. Gakis, D. V. Gold, Robert M. Sharkey, G. Mariani, Romano Bianchi, N. Molea, G. Brugnero, U. Boggi, David M. Goldenberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c281e1226a12970c5da8c239a9e229
http://hdl.handle.net/11568/707082
http://hdl.handle.net/11568/707082
Publikováno v:
Cancer research. 50(19)
A previous report described the production of monoclonal antibodies Mu-1, -2, -3, and -4 against colon-specific antigen p. We now report the tissue distribution of the reactive epitopes. Each of the monoclonal antibodies was reactive with epitopes sh
Autor:
R M, Sharkey, D V, Gold, R, Aninipot, R, Vagg, C, Ballance, E S, Newman, F, Ostella, H J, Hansen, D M, Goldenberg
Publikováno v:
Cancer research. 50
Tumor targeting of five radioiodinated murine monoclonal antibodies (MAbs) directed against human colorectal cancer were studied in nude mice bearing the GW-39 human colonic tumor xenograft. All of the MAbs are of the IgG1 isotype. Two of the MAbs (N
Publikováno v:
The Journal of Immunology. 126:2284-2289
CSAp was originally detected with antisera to an unfractionated extract of GW-39 human colonic carcinoma xenografts, and was determined to be restricted to normal and neoplastic gastrointestinal tissues and certain ovarian tumors. Gel filtration chro