Výsledky vyhledávání - "D V, Mishchenko"

Regioselective Synthesis, Structure, and Chemosensitizing Antitumor Activity of Cyclic Hydroxamic Acid Based on DL-Valine

Autor: Alexander V. Chernyak, T. E. Sashenkova, E. N. Klimanova, D. V. Mishchenko, Yu. R. Aleksandrova, Margarita E. Neganova, I. V. Vystorop, Gennady V. Shilov, U. Yu. Allayarova, Sergey G. Klochkov

Publikováno v: Russian Journal of Bioorganic Chemistry. 47:757-764

The reaction of DL-valine hydroxamic acid with triacetonamine proceeds as the N,N'-regioselective condensation to form (±)-1-hydroxy-3-isopropyl-7,7,9,9-tetramethyl-1,4,8-triazaspiro[4,5]decan-2-one. A study of the antimetastatic and antitumor activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a09840a6f1a1250acfbe60c971bcfe7
https://doi.org/10.1134/s1068162021030171

Zobrazit plný text záznamu

2-Ethyl-3-hydroxy-6-methylpyridine nitroxy succinate as a multifunctional hybrid structure

Autor: Z. V. Kuropteva, D. V. Mishchenko, V. R. Bogatyrenko, T. N. Bogatyrenko, L. M. Baider

Publikováno v: Russian Chemical Bulletin. 69:1999-2003

The effect of 2-ethyl-3-hydroxy-6-methylpyridine nitroxy succinate (1) on heart, brain, and liver tissues of experimental animals (C57/b1 mice) was studied by EPR. It was shown that compound 1, like nicorandil, increases the nitric oxide production i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02578f24d5b5a5d0675bf1ce90916773
https://doi.org/10.1007/s11172-020-2991-4

Zobrazit plný text záznamu

Thiophene-based water-soluble fullerene derivatives as highly potent antiherpetic pharmaceuticals

Autor: Dominique Schols, Alexander S. Peregudov, Olga A. Kraevaya, Klimova Rr, Alexander F. Shestakov, Pavel A. Troshin, N E Fedorova, Alla A. Kushch, D. V. Mishchenko, Ivan A. Godovikov

Publikováno v: Organic & Biomolecular Chemistry. 18:8702-8708

Here we report the Friedel-Crafts arylation of chlorofullerenes C60Cl6 and C70Cl8 with thiophene-based methyl esters. While C60Cl6 formed expected Cs-C60R5Cl products, C70Cl8 demonstrated a tendency for both substitution of chlorine atoms and additio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818d12798e6480fe93ee354038f4288e
https://doi.org/10.1039/d0ob01826k

Zobrazit plný text záznamu

Akademický článek

Features of quasi-brittle fracture of polymers and composites based on them

Autor: A. A. Valishin, D. V. Mishchenko

Publikováno v: Тонкие химические технологии, Vol 5, Iss 6, Pp 99-104 (2010)

Measurements of the crack's rostrum and strength in rostrum are defined. Form and measurements of constrained elasticity growing up in amorphous solid polymers in front of destruction crack at the temperatures higher then fragility temperature are de

Externí odkaz: https://doaj.org/article/9249fe852e99441194a8f79d11537bb0

Zobrazit plný text záznamu

Preparation, Antioxidant Properties and Ability to Increase Intracellular NO of a New Pyridoxine Derivative B6NO

Autor: A. B. Kornev, Margarita E. Neganova, Vera Amozova, Anastasia Balakina, Svyatoslav Gadomsky, D. V. Mishchenko, Boris Fedorov, Victoria Mumyatova, Ilya A. Yakushev, Tatyana Prikhodchenko, Tatyana Stupina

Publikováno v: Antioxidants
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1451, p 1451 (2021)

In the case of various pathologies, an imbalance between ROS generation and the endogenous AOS can be observed, which leads to excessive ROS accumulation, intensification of LPO processes, and oxidative stress. For the prevention of diseases associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ea9e44982c9b13242148d9e485ccd7

Zobrazit plný text záznamu

Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia

Autor: Sergey G. Klochkov, Margarita E. Neganova, Ghulam Md Ashraf, George E. Barreto, T. E. Sashenkova, Gjumrakch Aliev, Nagendra Sastry Yarla, E. N. Klimanova, Vadim V. Tarasov, I. V. Vystorop, Anna N. Samsonova, D. V. Mishchenko, Vladimir N. Chubarev, Elena F. Shevtsova

Publikováno v: Current Cancer Drug Targets. 18:365-371

Background: Anti-tumor effect of hydroxamic acid derivatives is largely connected with its properties as efficient inhibitors of histone deacetylases, and other metalloenzymes involved in carcinogenesis. Objective: The work was aimed to (i) determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c82e35e89ad52e1517593985c4da7f
https://doi.org/10.2174/1568009617666170623104030

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání