Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D V, Erbe"'
Autor:
K. Gartrell, D. Kubasiak, D. V. Erbe, Gideon Bollag, T. Gareski, Prabha N. Ibrahim, Womack Patrick, S. Wang, D.R. Artis, D. Panza, T. S. Mansour, J. F. Tobin, J. J. Lin, E. Saiah, G. P. Vlasuk, K. Harding, M. Perreault, S. Will, M. Jalenak
Publikováno v:
Diabetes, Obesity and Metabolism. 12:234-245
AIM Peroxisome proliferator activated receptors (PPARs) are nuclear receptors involved in glucose and lipid metabolism. Three isoforms of PPARs have been identified with different tissue distribution and biological functions. Although the pharmacolog
Autor:
S. Will, L. Kung, L. D. Klaman, J. F. Tobin, S. Tam, Douglas P. Wilson, Julie Lee, Zhao-Kui Wan, S. Wang, D. V. Erbe, Steven J. Kirincich, X. Xu
Publikováno v:
Diabetes, Obesity and Metabolism. 11:579-588
A growing percentage of the population is resistant to two key hormones - insulin and leptin - as a result of increased obesity, often leading to significant health consequences such as type 2 diabetes. Protein tyrosine phosphatase 1B (PTP1B) is a ke
Autor:
D V Erbe, L G Presta, R J Ramos, J M Rumberger, B N Rao, C Foxall, B K Brandley, B A Wolitzky, D K Burns, C R Norton
Publikováno v:
The Journal of Cell Biology. 119:215-227
E-selectin elicits cell adhesion by binding to the cell surface carbohydrate, sialyl Lewis X (sLe(x)). We evaluated the effects of mutations in the E-selectin lectin domain on the binding of a panel of anti-E-selectin mAbs and on the recognition of i
Publikováno v:
The Journal of Immunology. 147:3139-3144
It is known that antibodies to dengue viruses at subneutralizing concentrations enhance dengue virus infection of Fc gamma R+ cells. This phenomenon called antibody-dependent enhancement (ADE) occurs when virus-antibody complexes bind to the Fc gamma
Publikováno v:
The Journal of Immunology. 146:3145-3151
The three types of IgG FcR (Fc gamma RI, Fc gamma RII, Fc gamma RIII) on human leukocytes play an important role in elimination of antibody-coated infectious agents. To further understand the role of the different Fc gamma R in mediating this killing
Autor:
D V, Erbe, B A, Wolitzky, L G, Presta, C R, Norton, R J, Ramos, D K, Burns, J M, Rumberger, B N, Rao, C, Foxall, B K, Brandley
Publikováno v:
The Journal of Cell Biology
E-selectin elicits cell adhesion by binding to the cell surface carbohydrate, sialyl Lewis X (sLe(x)). We evaluated the effects of mutations in the E-selectin lectin domain on the binding of a panel of anti-E-selectin mAbs and on the recognition of i
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(9)
It is known that antibodies to dengue viruses at subneutralizing concentrations enhance dengue virus infection of Fc gamma R+ cells. This phenomenon called antibody-dependent enhancement (ADE) occurs when virus-antibody complexes bind to the Fc gamma
Publikováno v:
Immunology letters. 28(3)
There has been some controversy as to whether or not B cells can kill target cells through their Fc receptors. To address this, we have examined the ability of human B cells from a variety of sources to lyse hybridoma cells with specificity for eithe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(9)
The three types of IgG FcR (Fc gamma RI, Fc gamma RII, Fc gamma RIII) on human leukocytes play an important role in elimination of antibody-coated infectious agents. To further understand the role of the different Fc gamma R in mediating this killing
Publikováno v:
The Journal of Immunology. 143:3894-3900
To further understand the mechanism(s) of antibody-dependent cell-mediated cytotoxicity (ADCC) by various effector populations, we have examined the extracellular Ca++ and Mg++ requirements for ADCC performed by lymphocytes, monocytes, polymorphonucl