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pro vyhledávání: '"D Tozer"'
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Autor:
D Tozer, Lukas Pirpamer, Edith Hofer, Saima Hilal, Marco Duering, Robin G. Morris, Reinhold Schmidt, Hugh S. Markus, Anil M. Tuladhar, Christopher Chen, Marco Egle, Frank-Erik de Leeuw, James Wason, Martin Dichgans
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry 93(1), 14-23 (2022). doi:10.1136/jnnp-2021-326571
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 1, pp. 14-23
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 14-23
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 1, pp. 14-23
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 14-23
ObjectivesIt has been suggested that diffusion tensor imaging (DTI) measures sensitive to white matter (WM) damage may predict future dementia risk not only in cerebral small vessel disease (SVD), but also in mild cognitive impairment. To determine w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cee073bd244635732a03e337dcf23f
Autor:
John T. O'Brien, Gary A. Rosenberg, Jessica C. Walsh, Guy B. Williams, Hugh S. Markus, D Tozer, N. Jon Shah, Tim D. Fryer, Franklin I. Aigbirhio, Hasan Sari, Young T. Hong, Anna M. Drazyk
Publikováno v:
Brain 144(5), 1361-1371 (2021). doi:10.1093/brain/awab003
Cerebral small vessel disease (SVD) is a major cause of stroke and dementia. The underlying pathogenesis is poorly understood, but both neuroinflammation and increased blood–brain barrier permeability have been hypothesized to play a role, and prec
Publikováno v:
Stroke
Background and Purpose— Cerebrovascular disease contributes to age-related cognitive decline, but the mechanisms underlying this phenomenon remain incompletely understood. We hypothesized that vascular risk factors would lead to cognitive impairmen
Autor:
Giovanna Zamboni, Dorothee P. Auer, Nikola Sprigg, Ludovica Griffanti, Peter M. Rothwell, D Tozer, Mark Jenkinson, Robert A. Dineen, Iulius Dragonu, Fidel Alfaro-Almagro, Christoph Arthofer, Karla L. Miller, Hugh S. Markus, Vaanathi Sundaresan, Stamatios N. Sotiropoulos
Cerebral microbleeds (CMBs) appear as small, circular, well defined hypointense lesions of a few mm in size on T2*-weighted gradient recalled echo (T2*-GRE) images and appear enhanced on susceptibility weighted images (SWI). Due to their small size,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe4dbc12198908e44f03491d998b929
https://doi.org/10.1101/2021.09.21.21263298
https://doi.org/10.1101/2021.09.21.21263298
Autor:
D Tozer, Hugh S. Markus, Steven Bell, Stefania Nannoni, Stefan Gräf, Eric L. Harshfield, Bernard P H Cho
Publikováno v:
Journal of Neurology, Neurosurgery, and Psychiatry
BackgroundCysteine-altering NOTCH3 variants identical to those causing the rare monogenic form of stroke, CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), have been reported more common than expect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8c4f4a934c4190e398c3b473951842
https://www.repository.cam.ac.uk/handle/1810/318884
https://www.repository.cam.ac.uk/handle/1810/318884
Autor:
Cho Bp, Stefania Nannoni, Steven Bell, Stefan Gräf, Hugh S. Markus, D Tozer, Eric L. Harshfield
BackgroundCysteine-altering NOTCH3 variants identical to those causing the rare monogenic form of stroke, CADASIL, have been reported more common than expected in the general population, but their clinical significance and contribution to stroke and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b696c16f1e14e7e2a0d2b827c7ddb510
https://doi.org/10.1101/2020.12.14.20248151
https://doi.org/10.1101/2020.12.14.20248151
Publikováno v:
Neurology.
Background and ObjectivesTo determine the prevalence of and risk factors for cerebral microbleeds (CMBs) at different locations in a large healthy community population.MethodsA total of 8,159 participants from the UK Biobank with MRI scans suitable f
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 18, Iss, Pp 425-432 (2018)
NeuroImage: Clinical, Vol 18, Iss, Pp 425-432 (2018)
Objective MRI measures of network integrity may be useful disease markers in cerebral small vessel disease (SVD). We compared the sensitivity and reproducibility of MRI derived structural and functional network measures in healthy controls and SVD su
Autor:
D Tozer, Andrew M. Blamire, John T. O'Brien, Robin G. Morris, Hugh S. Markus, Anand Dixit, Gary A. Ford, Barry Moyhnihan, Thomas R. Barrick, Usman A. Khan, Iain D. Croall
Publikováno v:
Stroke. 49
Background and Aims: In patients with severe cerebral small vessel disease (SVD), in whom both cerebral blood flow and cerebral autoregulation are reduced, intensive BP lowering might reduce cerebral blood flow (CBF) and increase the rate of white ma