Targeted Metabolite Fingerprints of Thirteen Gambierdiscus, Five Coolia and Two Fukuyoa Species

Autor: J. Sam Murray, Emillie M. F. Passfield, Lesley L. Rhodes, Jonathan Puddick, Sarah C. Finch, Kirsty F. Smith, Roel van Ginkel, Elizabeth M. Mudge, Tomohiro Nishimura, Hiroshi Funaki, Masao Adachi, Michèle R. Prinsep, D. Tim Harwood

Publikováno v: Marine Drugs, Vol 22, Iss 3, p 119 (2024)

The genus Gambierdiscus produces an array of bioactive hydrophilic and lipophilic secondary metabolites that range in mode of action and toxicity. In this study, the metabolite fingerprint was mapped for thirteen Gambierdiscus, five Coolia and two Fu

Externí odkaz: https://doaj.org/article/70a761ea94be4023a528d0d094de7bba

A Sub-Acute Dosing Study of Saxitoxin and Tetrodotoxin Mixtures in Mice Suggests That the Current Paralytic Shellfish Toxin Regulatory Limit Is Fit for Purpose

Autor: Sarah C. Finch, Nicola G. Webb, Michael J. Boundy, D. Tim Harwood, John S. Munday, Jan M. Sprosen, Chanatda Somchit, Ric B. Broadhurst

Publikováno v: Toxins, Vol 15, Iss 7, p 437 (2023)

Paralytic shellfish poisoning is a worldwide problem induced by shellfish contaminated with paralytic shellfish toxins. To protect human health, a regulatory limit for these toxins in shellfish flesh has been adopted by many countries. In a recent st

Externí odkaz: https://doaj.org/article/dd55755bd3d94cf59e113fe41d66d81e

Functional significance of phylogeographic structure in a toxic benthic marine microbial eukaryote over a latitudinal gradient along the East Australian Current

Autor: Arjun Verma, David J. Hughes, D. Tim Harwood, David J. Suggett, Peter J. Ralph, Shauna A. Murray

Publikováno v: Ecology and Evolution, Vol 10, Iss 13, Pp 6257-6273 (2020)

Abstract Genetic diversity in marine microbial eukaryotic populations (protists) drives their ecological success by enabling diverse phenotypes to respond rapidly to changing environmental conditions. Despite enormous population sizes and lack of bar

Externí odkaz: https://doaj.org/article/5cf8e44ba4a940ac8d4e5d0227d62057

Interlaboratory Evaluation of Multiple LC-MS/MS Methods and a Commercial ELISA Method for Determination of Tetrodotoxin in Oysters and Mussels

Autor: Andrew D Turner, Karl J Dean, Monika Dhanji-Rapkova, Sonia Dall’Ara, Florella Pino, Claire McVey, Simon Haughey, Natasha Logan, Christopher Elliott, Ana Gago-Martinez, Jose Manuel Leao, Jorge Giraldez, Ryan Gibbs, Krista Thomas, Ruth Perez-Calderon, Dermot Faulkner, Hugh McEneny, Veronique Savar, Damien Reveillon, Philipp Hess, Fabiola Arevalo, J Pablo Lamas, Eva Cagide, Mercedes Alvarez, Alvaro Antelo, Mirjam D Klijnstra, Michalina Oplatowska-Stachowiak, Tim Kleintjens, Nermin Sajic, Michael J Boundy, Benjamin H Maskrey, D Tim Harwood, Jesús M González Jartín, Amparo Alfonso, Luis Botana

Publikováno v: Journal of AOAC International, 106(2), 356-369
Journal Of Aoac International (1060-3271) (Oxford University Press (OUP)), 2023-03, Vol. 106, N. 2, P. 356-369
Journal of AOAC International 106 (2023) 2

BackgroundGiven the recent detection of tetrodotoxin (TTX) in bivalve molluscs but the absence of a full collaborative validation study for TTX determination in a large number of shellfish samples, interlaboratory assessment of method performance was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540c5c6acedc883c5d846314f24345a1
https://doi.org/10.1093/jaoacint/qsad006

Update of the Planktonic Diatom Genus Pseudo-nitzschia in Aotearoa New Zealand Coastal Waters: Genetic Diversity and Toxin Production

Autor: Tomohiro Nishimura, J. Sam Murray, Michael J. Boundy, Muharrem Balci, Holly A. Bowers, Kirsty F. Smith, D. Tim Harwood, Lesley L. Rhodes

Publikováno v: Toxins, Vol 13, Iss 9, p 637 (2021)

Domoic acid (DA) is produced by almost half of the species belonging to the diatom genus Pseudo-nitzschia and causes amnesic shellfish poisoning (ASP). It is, therefore, important to investigate the diversity and toxin production of Pseudo-nitzschia

Externí odkaz: https://doaj.org/article/5f5b98290cb3421baa0b838a36872a5e