Zobrazeno 1 - 10
of 89
pro vyhledávání: '"D T Curiel"'
Autor:
Z B, Zhu, S K, Makhija, B, Lu, M, Wang, L, Kaliberova, B, Liu, A A, Rivera, D M, Nettelbeck, P J, Mahasreshti, C A, Leath, M, Yamamoto, M, Yamaoto, R D, Alvarez, D T, Curiel
Publikováno v:
Gene Therapy. 11:645-648
Adenoviral vectors are considered to be good gene delivery vectors for cancer gene therapy due to their wide host tissue range and cell cycle-independent infectivity. However, the disadvantages include the lack of specificity for cancer cells and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346d2613afdffd93df2c563808df3166
https://doi.org/10.1038/sj.gt.3302089
https://doi.org/10.1038/sj.gt.3302089
Autor:
D T, Curiel
Publikováno v:
Methods in molecular medicine. 7
Strategies have been developed to accomplish gene delivery via the receptor-mediated pathway employing molecular conjugate vectors (1-13). As cells possess endogenous pathways for internalization of macromolecules, the utilization of these pathways f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e42f66d45672e09edce9aabff7797027
https://pubmed.ncbi.nlm.nih.gov/24493415
https://pubmed.ncbi.nlm.nih.gov/24493415
Publikováno v:
Methods in molecular medicine. 35
The delineation of the molecular basis of cancer in general, allows for the possibility of specific intervention at the molecular level for therapeutic purposes. To this end, three main approaches have been developed: mutation compensation, molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::179d636fe0cac21cae68cf9b8f5d337a
https://pubmed.ncbi.nlm.nih.gov/21390804
https://pubmed.ncbi.nlm.nih.gov/21390804
Publikováno v:
Molecular and Cellular Biology. 10:47-56
The Mmineral springs alpha 1-antitrypsin (alpha 1AT) allele, causing alpha 1AT deficiency and emphysema, is unique among the alpha 1AT-deficiency alleles in that it was observed in a black family, whereas most mutations causing alpha 1AT deficiency a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae2ae3de6141268c0f6a7619a0bdbd6f
https://doi.org/10.1128/mcb.10.1.47
https://doi.org/10.1128/mcb.10.1.47
Publikováno v:
Cancer Gene Therapy. 22:222-222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a6391508aac754dcd72263bddb39986
https://doi.org/10.1038/cgt.2015.13
https://doi.org/10.1038/cgt.2015.13
Publikováno v:
Minerva ginecologica. 56(6)
Ovarian cancer has the highest mortality of all cancers of the female reproductive system. Although progress in conventional therapies (surgery, chemotherapy and irradiation) has been achieved, the 5-year survival rate for patients with advanced stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54cd4ccf17c2f385c123bdb7abb551e6
https://pubmed.ncbi.nlm.nih.gov/15729203
https://pubmed.ncbi.nlm.nih.gov/15729203
Autor:
H. G. van der POEL, B. MOLENAAR, V. W. van BEUSECHEM, H. J. HAISMA, R. RODRIGUEZ, D. T. CURIEL, W. R. GERRITSEN
Publikováno v:
The Journal of urology. 168(1)
We evaluated the delivery and oncolytic potential of targeted replication competent adenoviruses in bladder cancer lines.Seven established human bladder cancer tumor lines (5637, SW800, TCCsup, J82, Scaber, T24 and 253J) were studied for the expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f880e71b86158a8b06489e2f263285e
https://pubmed.ncbi.nlm.nih.gov/12050554
https://pubmed.ncbi.nlm.nih.gov/12050554
Publikováno v:
Cancer research. 61(23)
Replication-competent viruses are currently being evaluated for their cancer cell-killing properties. These vectors are designed to induce tumor regression after selective viral propagation within the tumor. However, replication-competent viruses hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fe3c8fcd5776aac617a56fe19986ba2
https://pubmed.ncbi.nlm.nih.gov/11731408
https://pubmed.ncbi.nlm.nih.gov/11731408
Autor:
Y, Adachi, P N, Reynolds, M, Yamamoto, M, Wang, K, Takayama, S, Matsubara, T, Muramatsu, D T, Curiel
Publikováno v:
Cancer research. 61(21)
The treatment of advanced neuroblastoma (NB) or Ewing's sarcoma (ES) is one of the major challenges in pediatric oncology. Both malignancies are refractory to conventional therapies and have an extremely poor prognosis. High-dose myeloablative radioc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c13ff6485f7a0f7c2ec2df0c47cb7eb
https://pubmed.ncbi.nlm.nih.gov/11691808
https://pubmed.ncbi.nlm.nih.gov/11691808
Autor:
K, Suzuki, D T, Curiel
Publikováno v:
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 53(4)
In spite of the advances achieved in cancer therapeutics, conventional therapies still face problems such as toxicity to normal tissues and low efficacy in advanced phases of the disease. One of the most recent options, albeit experimental, is gene t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0de2432fa29d5eb5b8b8d6228ac879a
https://pubmed.ncbi.nlm.nih.gov/11599483
https://pubmed.ncbi.nlm.nih.gov/11599483